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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:collagen-activated tyrosine kinase receptor signaling pathway
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Accession:GO:0038063 term browser browse the term
Definition:The series of molecular signals initiated by collagen binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: collagen-activated RTK signaling pathway;   collagen-activated tyrosine kinase receptor signalling pathway
 narrow_synonym: DDR signaling pathway;   discoidin domain receptor signaling pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi


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collagen-activated tyrosine kinase receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain acts_upstream_of_or_within IDA PMID:10970885 MGI PMID:10970885 RGD:11079513 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain acts_upstream_of_or_within ISO
IEA 		MGI:104688|MGI:2152695|MGI:88455|MGI:88456 (PMID:10970885)
GO_REF:0000107 		RGD
Ensembl		 PMID:10970885 GO_REF:0000107 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:104688|MGI:2152695|MGI:88456|MGI:88467 (PMID:10970885)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:10970885 GO_REF:0000033 GO_REF:0000107 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain acts_upstream_of_or_within ISO MGI:2152695|MGI:88455|MGI:88456|MGI:88467 (PMID:10970885) RGD PMID:10970885 NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895 		JBrowse link
G Col4a5 collagen type IV alpha 5 chain acts_upstream_of_or_within ISO MGI:104688|MGI:2152695|MGI:88455|MGI:88467 (PMID:10970885) RGD PMID:10970885 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692 		JBrowse link
G Col4a6 collagen type IV alpha 6 chain involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:104688|MGI:88455|MGI:88456|MGI:88467 (PMID:10970885) 		GO_Central
RGD		 PMID:10970885 GO_REF:0000033 NCBI chr  X:104,766,463...105,117,499
Ensembl chr  X:104,766,957...105,117,500 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 involved_in
acts_upstream_of_or_within 		ISO
ISS
IEP
IEA 		(PMID:12065315), (PMID:21044884), (PMID:9659899)
GO_REF:0000024
GO_REF:0000117
(PMID:10970885)
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:9659899 PMID:10970885 PMID:12065315 PMID:21044884 PMID:28199848 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117, RGD:151347403 NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO
IEA 		(PMID:16186108)
(PMID:11723120)
GO_REF:0000107
GO_REF:0000117 		RGD
Ensembl
UniProt		 PMID:11723120 PMID:16186108 GO_REF:0000107 GO_REF:0000117 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Gp6 glycoprotein VI acts_upstream_of_or_within ISO
IEA 		(PMID:27609517), (PMID:28032533)
GO_REF:0000107 		RGD
Ensembl		 PMID:27609517 PMID:28032533 GO_REF:0000107 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO
IEA 		(PMID:27609517)
GO_REF:0000107 		RGD
Ensembl		 PMID:27609517 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tspan9 tetraspanin 9 acts_upstream_of_or_within ISO MGI:4027164 (PMID:28032533) RGD PMID:28032533 NCBI chr 4:160,813,879...160,995,574
Ensembl chr 4:160,813,879...160,995,501 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:2670555 (PMID:27609517)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:27609517 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:50,282,510...50,430,034
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      signal transduction 7313
        cell surface receptor signaling pathway 2915
          collagen-activated signaling pathway 18
            collagen-activated tyrosine kinase receptor signaling pathway 12
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        regulation of cellular process 13032
          signal transduction 7313
            cell surface receptor signaling pathway 2915
              enzyme-linked receptor protein signaling pathway 1073
                cell surface receptor protein tyrosine kinase signaling pathway 681
                  collagen-activated tyrosine kinase receptor signaling pathway 12
paths to the root