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ONTOLOGY REPORT - ANNOTATIONS


Term:epidermal growth factor receptor ligand maturation
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Accession:GO:0038004 term browser browse the term
Definition:Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor.
Synonyms:exact_synonym: EGFR ligand maturation
 narrow_synonym: EGFR ligand maturation by peptide bond cleavage;   EGFR ligand processing;   peptide bond cleavage involved in EGFR ligand maturation
 related_synonym: epidermal growth factor receptor ligand processing;   peptide bond cleavage involved in epidermal growth factor receptor ligand maturation
 alt_id: GO:0038005



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epidermal growth factor receptor ligand maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 involved_in ISO (MGI:3037216|PMID:14993236), (MGI:3709108|PMID:17079736) RGD PMID:14993236 PMID:17079736 MGI:3037216 MGI:3709108 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889
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G Mep1a meprin A subunit alpha involved_in ISO (PMID:22923609) RGD PMID:22923609 NCBI chr 9:17,474,634...17,504,147
Ensembl chr 9:17,474,619...17,504,147
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      hormone metabolic process 248
        peptide hormone processing 24
          epidermal growth factor receptor ligand maturation 2
Path 2
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      nitrogen compound metabolic process 10349
        organonitrogen compound metabolic process 7049
          protein metabolic process 6117
            protein maturation 367
              protein processing 275
                signaling receptor ligand precursor processing 30
                  peptide hormone processing 24
                    epidermal growth factor receptor ligand maturation 2
paths to the root