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ONTOLOGY REPORT - ANNOTATIONS

Term:Derlin-1 retrotranslocation complex
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Accession:GO:0036513 term browser browse the term
Definition:A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.
Comment:The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.
Synonyms:exact_synonym: Derlin-1 complex;   Derlin-1 protein dislocation complex;   Derlin-1 retro-translocation complex;   Derlin-1 retrotranslocon;   ERAD protein dislocation complex


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Derlin-1 retrotranslocation complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amfr autocrine motility factor receptor part_of ISO (PMID:17872946) RGD PMID:17872946 NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247 		JBrowse link
G Derl1 derlin 1 part_of ISO (PMID:15215856), (PMID:17872946), (PMID:25239945) RGD PMID:15215856 PMID:17872946 PMID:25239945 NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Hm13 histocompatibility minor 13 part_of ISO (PMID:25239945) RGD PMID:25239945 NCBI chr 3:141,145,792...141,183,557
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:90,480,948...90,487,367
Ensembl chr 7:90,436,621...90,488,009 		JBrowse link
G Rnf139 ring finger protein 139 part_of ISO
IBA		 (PMID:25239945)
GO_REF:0000033		 RGD
GO_Central		 PMID:25239945 GO_REF:0000033 NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009 		JBrowse link
G Sel1l SEL1L adaptor subunit of SYVN1 ubiquitin ligase part_of ISO
IEA		 (PMID:21454652)
GO_REF:0000107		 RGD
Ensembl		 PMID:21454652 GO_REF:0000107 NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648 		JBrowse link
G Selenos selenoprotein S part_of ISO
IEA
IBA		 (PMID:15215856)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:15215856 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833 		JBrowse link
G Syvn1 synoviolin 1 part_of ISO (PMID:21454652) RGD PMID:21454652 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
G Vcp valosin-containing protein part_of ISO (PMID:15215856), (PMID:17872946)
(MGI:4441126|PMID:15215856)		 RGD PMID:15215856 PMID:17872946 MGI:4441126 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20814
    protein-containing complex 6438
      endoplasmic reticulum protein-containing complex 130
        Derlin-1 retrotranslocation complex 9
Path 2
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      organelle 14007
        intracellular organelle 13599
          intracellular membrane-bounded organelle 12057
            endoplasmic reticulum 1880
              endoplasmic reticulum subcompartment 1064
                endoplasmic reticulum membrane 1054
                  Derlin-1 retrotranslocation complex 9
paths to the root