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ONTOLOGY REPORT - ANNOTATIONS


Term:Derlin-1 retrotranslocation complex
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Accession:GO:0036513 term browser browse the term
Definition:A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.
Comment:The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.
Synonyms:exact_synonym: Derlin-1 complex;   Derlin-1 protein dislocation complex;   Derlin-1 retro-translocation complex;   Derlin-1 retrotranslocon;   ERAD protein dislocation complex



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Derlin-1 retrotranslocation complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amfr autocrine motility factor receptor part_of ISO (PMID:17872946) RGD PMID:17872946 NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247
JBrowse link
G Derl1 derlin 1 part_of ISO (PMID:15215856), (PMID:17872946), (PMID:25239945) RGD PMID:15215856 PMID:17872946 PMID:25239945 NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145
JBrowse link
G Hm13 histocompatibility minor 13 part_of ISO (PMID:25239945) RGD PMID:25239945 NCBI chr 3:141,145,769...141,184,703
Ensembl chr 3:141,145,782...141,184,703
JBrowse link
G Rnf139 ring finger protein 139 part_of ISO (PMID:25239945) RGD PMID:25239945 NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009
JBrowse link
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase part_of ISO
IEA
(PMID:21454652)
GO_REF:0000107
RGD
Ensembl
PMID:21454652 GO_REF:0000107 NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648
JBrowse link
G Selenos selenoprotein S part_of IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:15215856)
Ensembl
RGD
PMID:15215856 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833
JBrowse link
G Syvn1 synoviolin 1 part_of ISO (PMID:21454652) RGD PMID:21454652 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
JBrowse link
G Vcp valosin-containing protein part_of ISO (PMID:15215856), (PMID:17872946)
(MGI:4441126|PMID:15215856)
RGD PMID:15215856 PMID:17872946 MGI:4441126 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19896
    protein-containing complex 5946
      endoplasmic reticulum protein-containing complex 138
        Derlin-1 retrotranslocation complex 8
Path 2
Term Annotations click to browse term
  cellular_component 19896
    cellular anatomical entity 19599
      organelle 13017
        intracellular organelle 12666
          intracellular membrane-bounded organelle 11161
            endoplasmic reticulum 1756
              endoplasmic reticulum subcompartment 959
                endoplasmic reticulum membrane 949
                  Derlin-1 retrotranslocation complex 8
paths to the root