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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of translation in response to endoplasmic reticulum stress
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Accession:GO:0036490 term browser browse the term
Definition:Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
Synonyms:exact_synonym: regulation of translation in response to ER stress



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eiF2alpha phosphorylation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:6467680|PMID:17707796)
(PMID:25329545)
UniProt
RGD
PMID:17707796 PMID:25329545 GO_REF:0000024 MGI:6467680 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (PMID:25329545) RGD PMID:25329545 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630
JBrowse link
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISO
ISS
(PMID:22064321)
(MGI:5617428|PMID:25329545)
GO_REF:0000024
RGD
UniProt
PMID:22064321 PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA
(PMID:14676213), (PMID:16835242)
PMID:21873635
UniProtKB:O55033 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)
RGD PMID:14676213 PMID:16835242 PMID:21873635 MGI:5613475 MGI:5613478, RGD:13792537 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA
(PMID:16835242)
PMID:21873635
UniProtKB:Q99M51 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)
RGD PMID:14676213 PMID:16835242 PMID:21873635 MGI:5613475 MGI:5613478, RGD:13792537 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B involved_in ISO (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO MGI:4456438 (MGI:5914333|PMID:28797121) RGD PMID:28797121 MGI:5914333 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903
JBrowse link
negative regulation of translation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:1333015|PMID:9930704) RGD PMID:9930704 MGI:1333015 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:24947615)
(MGI:5688277|PMID:24947615)
RGD PMID:24947615 MGI:5688277 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:21518769) RGD PMID:21518769 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
positive regulation of translation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:29062139) RGD PMID:29062139 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 involved_in ISO (PMID:29062139) RGD PMID:29062139 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA
(PMID:14676213)
PMID:21873635
UniProtKB:O55033 (MGI:5613478|PMID:14676213)
RGD PMID:14676213 PMID:21873635 MGI:5613478, RGD:13792537 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA
UniProtKB:Q99M51 (MGI:5613478|PMID:14676213)
PMID:21873635
RGD PMID:14676213 PMID:21873635 MGI:5613478, RGD:13792537 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307
JBrowse link
positive regulation of translation initiation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5617428|PMID:25329545)
UniProt
RGD
PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3582244|PMID:11106749)
UniProt
RGD
PMID:11106749 GO_REF:0000024 MGI:3582244 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:5605960 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    response to stimulus 10416
      response to stress 4097
        cellular response to stress 2000
          response to endoplasmic reticulum stress 260
            regulation of translation in response to endoplasmic reticulum stress 11
              negative regulation of translation in response to endoplasmic reticulum stress + 2
              positive regulation of translation in response to endoplasmic reticulum stress + 5
              regulation of translation initiation in response to endoplasmic reticulum stress + 8
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      nitrogen compound metabolic process 9994
        cellular nitrogen compound metabolic process 6560
          cellular amide metabolic process 1500
            peptide metabolic process 1238
              peptide biosynthetic process 1071
                translation 1051
                  regulation of translation 403
                    regulation of translation in response to stress 21
                      regulation of translation in response to endoplasmic reticulum stress 11
                        negative regulation of translation in response to endoplasmic reticulum stress + 2
                        positive regulation of translation in response to endoplasmic reticulum stress + 5
                        regulation of translation initiation in response to endoplasmic reticulum stress + 8
paths to the root