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ONTOLOGY REPORT - ANNOTATIONS


Term:cell death in response to oxidative stress
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Accession:GO:0036473 term browser browse the term
Definition:Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus.
Comment:This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred in response to an oxidative stress stimulus, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0097468 'programmed cell death in response to reactive oxygen species'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.


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cell death in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta NOT ISO (PMID:25456120) RGD PMID:25456120 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Rnf112 ring finger protein 112 ISS
ISO
GO_REF:0000024
(MGI:MGI:6154496|PMID:27918959)
UniProt
RGD
PMID:27918959 GO_REF:0000024, MGI:MGI:6154496 NCBI chr10:47,719,034...47,726,050
Ensembl chr10:47,719,014...47,725,172
JBrowse link
cell death in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf112 ring finger protein 112 ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:6154438|PMID:26792191)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:26792191 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6154438 NCBI chr10:47,719,034...47,726,050
Ensembl chr10:47,719,014...47,725,172
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:6154438|PMID:26792191)
UniProt
RGD
PMID:26792191 GO_REF:0000024, MGI:MGI:6154438 NCBI chr 5:58,121,824...58,124,687
Ensembl chr 5:58,121,786...58,124,681
JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd10 programmed cell death 10 ISO UniProtKB:O00506 (PMID:22652780) RGD PMID:22652780 NCBI chr 2:173,966,701...174,012,730
Ensembl chr 2:173,967,080...174,012,676
JBrowse link
G Stk25 serine/threonine kinase 25 ISO UniProtKB:Q9BUL8 (PMID:22652780) RGD PMID:22652780 NCBI chr 9:100,767,578...100,779,715
Ensembl chr 9:100,767,579...100,779,715
JBrowse link
intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IMP protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 IEA
ISO
GO_REF:0000107
(PMID:18387645)
Ensembl
RGD
PMID:18387645 GO_REF:0000107 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO
IEA
(MGI:MGI:2679141|PMID:12855558)
GO_REF:0000107
RGD
Ensembl
PMID:12855558 GO_REF:0000107, MGI:MGI:2679141 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:5492227|PMID:23568032), (MGI:MGI:5544856|PMID:23979599)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23568032, PMID:23979599 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5492227, MGI:MGI:5544856 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO
IBA
(MGI:MGI:3587135|PMID:16085184)
PMID:21873635
RGD PMID:16085184, PMID:21873635 MGI:MGI:3587135, RGD:13792537 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO MGI:MGI:2158814 (MGI:MGI:2153292|PMID:11562367), (MGI:MGI:3613414|PMID:15663476) RGD PMID:11562367, PMID:15663476 MGI:MGI:2153292, MGI:MGI:3613414 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gskip GSK3B interacting protein IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:25920809)
Ensembl
UniProt
RGD
PMID:25920809 GO_REF:0000024, GO_REF:0000107 NCBI chr 6:129,512,950...129,536,320
Ensembl chr 6:129,519,709...129,536,221
JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:15659221 RGD:1641883 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G LOC100360940 diablo-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:147,607,350...147,608,936
Ensembl chr 5:147,607,552...147,609,050
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO
IBA
(MGI:MGI:3829088|PMID:18948261)
(PMID:21771788), (PMID:26095851)
PMID:21873635
RGD PMID:18948261, PMID:21771788, PMID:26095851, PMID:21873635 MGI:MGI:3829088, RGD:13792537 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapt microtubule-associated protein tau IDA RGD PMID:12420308 RGD:8158111 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Melk maternal embryonic leucine zipper kinase ISO (MGI:MGI:3829088|PMID:18948261) RGD PMID:18948261 MGI:MGI:3829088 NCBI chr 5:59,783,835...59,844,356
Ensembl chr 5:59,783,890...59,844,356
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:18541534)
Ensembl
UniProt
RGD
PMID:18541534 GO_REF:0000024, GO_REF:0000107 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pml PML nuclear body scaffold ISO (MGI:MGI:4849347|PMID:21030605) RGD PMID:21030605 MGI:MGI:4849347 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Rnf7 ring finger protein 7 ISO (MGI:MGI:1333612|PMID:10082581) RGD PMID:10082581 MGI:MGI:1333612 NCBI chr 8:104,326,719...104,336,098
Ensembl chr 8:104,326,719...104,335,729
JBrowse link
G Sod2 superoxide dismutase 2 ISO MGI:MGI:1857480 (MGI:MGI:3691744|PMID:15642323) RGD PMID:15642323 MGI:MGI:3691744 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Stk24 serine/threonine kinase 24 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19604147)
Ensembl
UniProt
RGD
PMID:19604147 GO_REF:0000024, GO_REF:0000107 NCBI chr15:106,629,258...106,678,917
Ensembl chr15:106,629,312...106,678,918
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats ISO MGI:MGI:3043446 (MGI:MGI:3056865|PMID:15271982) RGD PMID:15271982 MGI:MGI:3056865 NCBI chr 8:65,686,586...65,774,940
Ensembl chr 8:65,686,648...65,774,989
JBrowse link
G Zfp622 zinc finger protein 622 ISO (PMID:21771788) RGD PMID:21771788 NCBI chr 2:78,407,312...78,421,152
Ensembl chr 2:78,407,414...78,421,024
JBrowse link
negative regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epor erythropoietin receptor IMP RGD PMID:23636173 RGD:10401070 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO (MGI:MGI:5586790|PMID:23690594) RGD PMID:23690594 MGI:MGI:5586790 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 ISO
IEA
(MGI:MGI:5586790|PMID:23690594)
GO_REF:0000107
RGD
Ensembl
PMID:23690594 GO_REF:0000107, MGI:MGI:5586790 NCBI chr13:51,985,698...51,992,547
Ensembl chr13:51,985,684...51,992,693
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:10329212 RGD:10059424 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:24576675) RGD PMID:24576675 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO UniProtKB:Q99497 (PMID:22492997) RGD PMID:22492997 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ngb neuroglobin IMP RGD PMID:18083144 RGD:9743949 NCBI chr 6:111,126,259...111,131,699
Ensembl chr 6:111,126,261...111,132,320
JBrowse link
G Nol3 nucleolar protein 3 IMP
IDA
PMID:16639714
PMID:17292893
UniProt PMID:16639714, PMID:17292893 RGD:10047164, RGD:10047212 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Park7 Parkinsonism associated deglycase ISO (PMID:22492997), (PMID:23743200) RGD PMID:22492997, PMID:23743200 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pde8a phosphodiesterase 8A ISO (PMID:23509299) RGD PMID:23509299 NCBI chr 1:143,036,083...143,160,395
Ensembl chr 1:143,036,218...143,159,433
JBrowse link
G Psap prosaposin ISO
IEA
(MGI:MGI:5586790|PMID:23690594)
GO_REF:0000107
RGD
Ensembl
PMID:23690594 GO_REF:0000107, MGI:MGI:5586790 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Rnf146 ring finger protein 146 IDA RGD PMID:24842055 RGD:13524867 NCBI chr 1:30,856,923...30,873,814
Ensembl chr 1:30,863,217...30,873,808
JBrowse link
G Txn1 thioredoxin 1 ISO
IEA
UniProtKB:Q99497 (PMID:22492997)
GO_REF:0000107
RGD
Ensembl
PMID:22492997 GO_REF:0000107 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
negative regulation of hydrogen peroxide-induced neuron death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 ISO (PMID:26310625) RGD PMID:26310625 NCBI chr 7:23,815,246...23,843,505
Ensembl chr 7:23,815,245...23,843,634
JBrowse link
G Il10 interleukin 10 ISO ComplexPortal:CPX-1134 (MGI:MGI:5291547|PMID:21857966) RGD PMID:21857966 MGI:MGI:5291547 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 ISO
ISS
(MGI:MGI:4462723|PMID:20566846)
GO_REF:0000024
RGD
UniProt
PMID:20566846 GO_REF:0000024, MGI:MGI:4462723 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Park7 Parkinsonism associated deglycase ISO (MGI:MGI:5574514|PMID:24947010)
(PMID:15983381), (PMID:24947010)
RGD PMID:15983381, PMID:24947010 MGI:MGI:5574514 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Rack1 receptor for activated C kinase 1 ISO UniProtKB:Q99497 (PMID:24947010)
UniProtKB:Q99497 (MGI:MGI:5574514|PMID:24947010)
RGD PMID:24947010 MGI:MGI:5574514 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Reg3b regenerating family member 3 beta IDA RGD PMID:21643999 RGD:9831400 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO
IEA
UniProtKB:Q99LX0 (PMID:14652021)
GO_REF:0000107
(MGI:MGI:5613479|PMID:14652021)
RGD
Ensembl
PMID:14652021 GO_REF:0000107, MGI:MGI:5613479 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249, PMID:23261939 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
negative regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glrx glutaredoxin IMP RGD PMID:19938943 RGD:9686063 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Hgf hepatocyte growth factor ISO (PMID:20655899) RGD PMID:20655899 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hk3 hexokinase 3 IDA PMID:21072205 CACAO PMID:21072205 RGD:10047370 NCBI chr17:10,134,726...10,152,976
Ensembl chr17:10,137,974...10,152,956
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO
IEA
(PMID:20655899)
GO_REF:0000107
RGD
Ensembl
PMID:20655899 GO_REF:0000107 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsph1 heat shock protein family H (Hsp110) member 1 ISO (MGI:MGI:3822965|PMID:18681888) RGD PMID:18681888 MGI:MGI:3822965 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Pink1 PTEN induced kinase 1 IMP
ISO
PMID:17579517
(PMID:17579517)
RGD PMID:17579517, PMID:17579517 RGD:8693356 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Trap1 TNF receptor-associated protein 1 IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,724,032...11,757,682
Ensembl chr10:11,724,032...11,757,681
JBrowse link
negative regulation of oxidative stress-induced cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fyn FYN proto-oncogene, Src family tyrosine kinase IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gata4 GATA binding protein 4 ISO (MGI:MGI:5780531|PMID:25590961) RGD PMID:25590961 MGI:MGI:5780531 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IMP RGD PMID:11522747 RGD:10402752 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Park7 Parkinsonism associated deglycase ISO (PMID:16632486) RGD PMID:16632486 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:16632486) RGD PMID:16632486 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:136,180,640...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO
IEA
MGI:MGI:2158814 (MGI:MGI:3698597|PMID:16373599)
GO_REF:0000107
RGD
Ensembl
PMID:16373599 GO_REF:0000107, MGI:MGI:3698597 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO
IEA
(MGI:MGI:3581090|PMID:15731106)
GO_REF:0000107
RGD
Ensembl
PMID:15731106 GO_REF:0000107, MGI:MGI:3581090 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO (PMID:23043106) RGD PMID:23043106 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nme5 NME/NM23 family member 5 ISO
IBA
(MGI:MGI:2664629|PMID:12788088)
PMID:21873635
RGD PMID:12788088, PMID:21873635 MGI:MGI:2664629, RGD:13792537 NCBI chr18:27,357,460...27,374,641
Ensembl chr18:27,357,413...27,374,603
JBrowse link
G Nol3 nucleolar protein 3 ISO
IEA
(PMID:15004034)
GO_REF:0000107
RGD
Ensembl
PMID:15004034 GO_REF:0000107 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Ppia peptidylprolyl isomerase A ISO
ISS
(PMID:26095851)
GO_REF:0000024
RGD
UniProt
PMID:26095851 GO_REF:0000024 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:22,706,906...22,707,648
Ensembl chr14:22,706,901...22,707,668
JBrowse link
G Sirt1 sirtuin 1 ISO
IEA
(PMID:17317627)
GO_REF:0000107
RGD
Ensembl
PMID:17317627 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sod2 superoxide dismutase 2 ISO (PMID:12551919) RGD PMID:12551919 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Vnn1 vanin 1 ISO (MGI:MGI:3052282|PMID:15282320) RGD PMID:15282320 MGI:MGI:3052282 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
negative regulation of oxidative stress-induced neuron death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 ISO
IMP
UniProtKB:Q9ES19 (PMID:23392669) RGD PMID:23392669, PMID:23392669 RGD:10047168 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg7 autophagy related 7 IMP RGD PMID:25639566 RGD:11553824 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Ctnnb1 catenin beta 1 ISO
IEA
(MGI:MGI:5770063|PMID:21752258)
GO_REF:0000107
RGD
Ensembl
PMID:21752258 GO_REF:0000107, MGI:MGI:5770063 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Fbxo7 F-box protein 7 ISO
IBA
(PMID:25029497)
PMID:21873635
RGD PMID:25029497, PMID:21873635 RGD:13792537 NCBI chr 7:23,815,246...23,843,505
Ensembl chr 7:23,815,245...23,843,634
JBrowse link
G Fzd1 frizzled class receptor 1 ISO
IEA
(MGI:MGI:5770063|PMID:21752258)
GO_REF:0000107
RGD
Ensembl
PMID:21752258 GO_REF:0000107, MGI:MGI:5770063 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:9538214 RGD:9685737 NCBI chr10:14,059,347...14,061,703
Ensembl chr10:14,059,347...14,061,703
JBrowse link
G Meak7 MTOR associated protein, eak-7 homolog ISO (MGI:MGI:5766554|PMID:26668325) RGD PMID:26668325 MGI:MGI:5766554 NCBI chr19:52,408,700...52,430,198
Ensembl chr19:52,408,917...52,424,318
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 ISO
IBA
(MGI:MGI:5766554|PMID:26668325)
PMID:21873635
RGD PMID:26668325, PMID:21873635 MGI:MGI:5766554, RGD:13792537 NCBI chr 1:29,225,727...29,386,642
Ensembl chr 1:29,225,707...29,385,199
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 ISO UniProtKB:Q06219 (MGI:MGI:4462723|PMID:20566846) RGD PMID:20566846 MGI:MGI:4462723 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Oxr1 oxidation resistance 1 ISO
IBA
IEA
(MGI:MGI:5766554|PMID:26668325)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:26668325, PMID:21873635 GO_REF:0000107, MGI:MGI:5766554, RGD:13792537 NCBI chr 7:80,351,774...80,788,094
Ensembl chr 7:80,351,774...80,788,094
JBrowse link
G Park7 Parkinsonism associated deglycase ISO (MGI:MGI:5575789|PMID:24899725) RGD PMID:24899725 MGI:MGI:5575789 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IGI PMID:23392669 ParkinsonsUK-UCL PMID:23392669 RGD:10047168 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Rest RE1-silencing transcription factor ISS
ISO
GO_REF:0000024
(PMID:24670762)
UniProt
RGD
PMID:24670762 GO_REF:0000024 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
G Slc7a11 solute carrier family 7 member 11 ISO MGI:MGI:1857061 (MGI:MGI:3664848|PMID:17035536) RGD PMID:17035536 MGI:MGI:3664848 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Tbc1d24 TBC1 domain family, member 24 ISO (MGI:MGI:5766554|PMID:26668325) RGD PMID:26668325 MGI:MGI:5766554 NCBI chr10:13,551,100...13,576,739
Ensembl chr10:13,551,100...13,558,384
JBrowse link
G Tldc2 TBC/LysM-associated domain containing 2 ISO
IBA
(MGI:MGI:5766554|PMID:26668325)
PMID:21873635
RGD PMID:26668325, PMID:21873635 MGI:MGI:5766554, RGD:13792537 NCBI chr 3:153,195,295...153,208,118
Ensembl chr 3:153,197,644...153,207,816
JBrowse link
G Tsc1 TSC complex subunit 1 IMP RGD PMID:23435171 RGD:10448950 NCBI chr 3:7,219,955...7,269,063
Ensembl chr 3:7,237,192...7,265,145
JBrowse link
G Wnt1 Wnt family member 1 ISO (MGI:MGI:5770063|PMID:21752258) RGD PMID:21752258 MGI:MGI:5770063 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha ISO
IEA
(PMID:24899725)
GO_REF:0000107
RGD
Ensembl
PMID:24899725 GO_REF:0000107 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Nono non-POU domain containing, octamer-binding ISO (PMID:15790595) RGD PMID:15790595 NCBI chr  X:71,324,365...71,342,225
Ensembl chr  X:71,324,365...71,342,225
JBrowse link
G Park7 Parkinsonism associated deglycase ISO
ISS
(PMID:15790595)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:15790595 GO_REF:0000024 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO
ISS
(PMID:17314283)
GO_REF:0000024
(MGI:MGI:5543313|PMID:23858059)
RGD
ParkinsonsUK-UCL
PMID:17314283, PMID:23858059 GO_REF:0000024, MGI:MGI:5543313 NCBI chr 1:48,880,015...50,069,998 JBrowse link
neuron death in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 ISO MGI:MGI:5315599 (MGI:MGI:5315235|PMID:22210510) RGD PMID:22210510 MGI:MGI:5315235 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Endog endonuclease G IEP RGD PMID:23006905 RGD:9685394 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Slc1a1 solute carrier family 1 member 1 ISO (MGI:MGI:6393184|PMID:25350110) RGD PMID:25350110 MGI:MGI:6393184 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
JBrowse link
G Tbc1d24 TBC1 domain family, member 24 ISO (PMID:30335140)
MGI:MGI:5692831 (MGI:MGI:6279048|PMID:30335140)
RGD PMID:30335140 MGI:MGI:6279048 NCBI chr10:13,551,100...13,576,739
Ensembl chr10:13,551,100...13,558,384
JBrowse link
positive regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 IMP cardiac muscle cell RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO (PMID:20550618) RGD PMID:20550618 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
positive regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase IMP RGD PMID:21715626 RGD:8693407 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Endog endonuclease G IMP RGD PMID:20594982 RGD:9685387 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Foxo3 forkhead box O3 IMP RGD PMID:23585551 RGD:7327146 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Hdac6 histone deacetylase 6 ISO (PMID:18606987) RGD PMID:18606987 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO
IEA
(MGI:MGI:5648604|PMID:25472717)
GO_REF:0000107
RGD
Ensembl
PMID:25472717 GO_REF:0000107, MGI:MGI:5648604 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
positive regulation of oxidative stress-induced cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcar Fc fragment of IgA receptor ISO (PMID:25339672) RGD PMID:25339672 NCBI chr 1:73,230,392...73,263,462
Ensembl chr 1:73,230,390...73,264,302
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO (MGI:MGI:5575467|PMID:20969476) RGD PMID:20969476 MGI:MGI:5575467 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 ISO
IEA
MGI:MGI:3616995 (MGI:MGI:4881403|PMID:19661248)
GO_REF:0000107
RGD
Ensembl
PMID:19661248 GO_REF:0000107, MGI:MGI:4881403 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Park7 Parkinsonism associated deglycase ISO (MGI:MGI:5543357|PMID:22555455) RGD PMID:22555455 MGI:MGI:5543357 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Sfpq splicing factor proline and glutamine rich ISO (PMID:15790595) RGD PMID:15790595 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sod1 superoxide dismutase 1 ISO (PMID:12551919) RGD PMID:12551919 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
positive regulation of oxidative stress-induced neuron death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO UniProtKB:Q9EPW9|UniProtKB:Q9QUK6 (PMID:20037584) RGD PMID:20037584 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Hdac6 histone deacetylase 6 IMP RGD PMID:19884510 RGD:9681717 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Itgam integrin subunit alpha M ISO (MGI:MGI:3814938|PMID:18981141) RGD PMID:18981141 MGI:MGI:3814938 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Rest RE1-silencing transcription factor IMP PMID:22371606 UniProt PMID:22371606 RGD:14397566 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
G Tlr4 toll-like receptor 4 IEA
ISO
GO_REF:0000107
UniProtKB:P05067:PRO_0000000092 (MGI:MGI:4438693|PMID:20037584)
Ensembl
RGD
PMID:20037584 GO_REF:0000107, MGI:MGI:4438693 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr6 toll-like receptor 6 ISO UniProtKB:P05067:PRO_0000000092 (MGI:MGI:4438693|PMID:20037584) RGD PMID:20037584 MGI:MGI:4438693 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446
JBrowse link
G Tnf tumor necrosis factor IDA RGD PMID:15713255 RGD:1580210 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 IDA RGD PMID:16651700 RGD:9999433 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxw7 F-box and WD repeat domain containing 7 ISO (PMID:23858059)
(MGI:MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:MGI:5543313 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member ISO UniProtKB:Q9WVS6 (PMID:23858059)
(MGI:MGI:5543313|PMID:23858059)
RGD PMID:23858059 MGI:MGI:5543313 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
programmed cell death in response to reactive oxygen species term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pjvk pejvakin ISO (MGI:MGI:6294584|PMID:30936319) RGD PMID:30936319 MGI:MGI:6294584 NCBI chr 3:63,508,386...63,518,163
Ensembl chr 3:63,510,293...63,518,147
JBrowse link
regulation of hydrogen peroxide-induced cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stk26 serine/threonine kinase 26 ISO (PMID:22291017) RGD PMID:22291017 NCBI chr  X:138,032,356...138,096,632
Ensembl chr  X:138,046,494...138,096,669
JBrowse link
G Tp53 tumor protein p53 IMP PMID:17998337 UniProt PMID:17998337 RGD:10047225 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P4hb prolyl 4-hydroxylase subunit beta ISO (PMID:12095988) RGD PMID:12095988 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Ubqln1 ubiquilin 1 ISO
ISS
IEA
(PMID:12095988)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:12095988 GO_REF:0000024, GO_REF:0000107 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844
JBrowse link
regulation of oxidative stress-induced neuron death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lancl1 LanC like 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:5604031|PMID:25158856)
UniProt
RGD
PMID:25158856 GO_REF:0000024, MGI:MGI:5604031 NCBI chr 9:74,018,192...74,048,098
Ensembl chr 9:74,014,656...74,048,244
JBrowse link
G Rest RE1-silencing transcription factor IMP PMID:12657670 UniProt PMID:12657670 RGD:1299303 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:17347665 RGD:10414071 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell death 2137
        cell death in response to oxidative stress 106
          cell death in response to hydrogen peroxide + 39
          intrinsic apoptotic signaling pathway in response to oxidative stress + 47
          negative regulation of oxidative stress-induced cell death + 55
          neuron death in response to oxidative stress + 39
          positive regulation of oxidative stress-induced cell death + 23
          programmed cell death in response to reactive oxygen species + 16
          regulation of oxidative stress-induced cell death + 82
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular response to stimulus 8920
        cellular response to stress 1982
          cellular response to chemical stress 419
            cellular response to oxidative stress 348
              cell death in response to oxidative stress 106
                cell death in response to hydrogen peroxide + 39
                intrinsic apoptotic signaling pathway in response to oxidative stress + 47
                negative regulation of oxidative stress-induced cell death + 55
                neuron death in response to oxidative stress + 39
                positive regulation of oxidative stress-induced cell death + 23
                programmed cell death in response to reactive oxygen species + 16
                regulation of oxidative stress-induced cell death + 82
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.