Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:TRAIL-activated apoptotic signaling pathway
go back to main search page
Accession:GO:0036462 term browser browse the term
Definition:An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface.
Synonyms:exact_synonym: TRAIL-activated extrinsic apoptotic signaling pathway;   TRAIL-induced apoptotic signaling pathway;   tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway


show annotations for term's descendants       view all columns           Sort by:
 
TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CASP8 caspase 8 JBrowse link 15 104,923,659 104,948,470 RGD:14298760
G FADD Fas associated via death domain JBrowse link 2 3,191,718 3,194,820 RGD:14298760
G LOC100624226 tumor necrosis factor receptor superfamily member 10A-like JBrowse link 14 7,256,588 7,291,998 RGD:14298760
negative regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
positive regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATF3 activating transcription factor 3 JBrowse link 9 130,772,259 130,829,678 RGD:14298760
G TIMP3 TIMP metallopeptidase inhibitor 3 JBrowse link 5 12,185,816 12,242,599 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15162
    signaling 5495
      signal transduction 5109
        apoptotic signaling pathway 439
          extrinsic apoptotic signaling pathway 166
            extrinsic apoptotic signaling pathway via death domain receptors 58
              TRAIL-activated apoptotic signaling pathway 6
                TRAIL death-inducing signaling complex assembly 0
                negative regulation of TRAIL-activated apoptotic signaling pathway 1
                positive regulation of TRAIL-activated apoptotic signaling pathway 2
                regulation of TRAIL-activated apoptotic signaling pathway + 3
Path 2
Term Annotations click to browse term
  biological_process 15162
    cellular process 14331
      cell death 1250
        programmed cell death 1169
          apoptotic process 1138
            apoptotic signaling pathway 439
              extrinsic apoptotic signaling pathway 166
                extrinsic apoptotic signaling pathway via death domain receptors 58
                  TRAIL-activated apoptotic signaling pathway 6
                    TRAIL death-inducing signaling complex assembly 0
                    negative regulation of TRAIL-activated apoptotic signaling pathway 1
                    positive regulation of TRAIL-activated apoptotic signaling pathway 2
                    regulation of TRAIL-activated apoptotic signaling pathway + 3
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.