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ONTOLOGY REPORT - ANNOTATIONS


Term:ESCRT complex
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Accession:GO:0036452 term browser browse the term
Definition:An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes.
Synonyms:exact_synonym: endosomal sorting complex required for transport
 xref: Wikipedia:ESCRT


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ESCRT I complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mvb12a multivesicular body subunit 12A ISO
IBA
(PMID:18005716), (PMID:20654576), (PMID:22232651)
PMID:21873635
RGD PMID:18005716, PMID:20654576, PMID:22232651, PMID:21873635 RGD:13792537 NCBI chr16:19,973,611...19,978,479
Ensembl chr16:19,973,636...19,978,478
JBrowse link
G Mvb12b multivesicular body subunit 12B ISO
IBA
(PMID:18005716), (PMID:20654576)
PMID:21873635
RGD PMID:18005716, PMID:20654576, PMID:21873635 RGD:13792537 NCBI chr 3:12,780,196...12,944,542
Ensembl chr 3:12,780,100...12,944,494
JBrowse link
G Tsg101 tumor susceptibility 101 ISS
ISO
GO_REF:0000024
(PMID:18005716), (PMID:20654576), (PMID:21757351), (PMID:22232651)
UniProt
RGD
PMID:18005716, PMID:20654576, PMID:21757351, PMID:22232651 GO_REF:0000024 NCBI chr 1:102,941,151...102,971,017
Ensembl chr 1:102,941,231...102,970,950
JBrowse link
G Ubap1 ubiquitin-associated protein 1 ISO
IBA
ISS
(PMID:21757351)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:21757351, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:57,738,309...57,778,724
Ensembl chr 5:57,738,321...57,778,723
JBrowse link
G Ubap1l ubiquitin associated protein 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:70,876,516...70,895,723
Ensembl chr 8:70,884,491...70,896,501
JBrowse link
G Vps28 VPS28 subunit of ESCRT-I ISS
IBA
ISO
IEA
GO_REF:0000024
PMID:21873635
(PMID:18005716), (PMID:20654576), (PMID:21757351), (PMID:22232651)
GO_REF:0000104
UniProt
RGD
PMID:18005716, PMID:20654576, PMID:21757351, PMID:22232651, PMID:21873635 GO_REF:0000024, GO_REF:0000104, RGD:13792537 NCBI chr 7:117,684,339...117,688,187
Ensembl chr 7:117,684,339...117,688,187
JBrowse link
G Vps37a VPS37A subunit of ESCRT-I ISO
IBA
(PMID:18005716), (PMID:20654576), (PMID:21757351)
PMID:21873635
RGD PMID:18005716, PMID:20654576, PMID:21757351, PMID:21873635 RGD:13792537 NCBI chr16:54,860,811...54,899,410
Ensembl chr16:54,860,868...54,899,347
JBrowse link
G Vps37b VPS37B subunit of ESCRT-I ISO
IBA
(PMID:18005716), (PMID:22232651), (PMID:22405001)
PMID:21873635
RGD PMID:18005716, PMID:22232651, PMID:22405001, PMID:21873635 RGD:13792537 NCBI chr12:37,984,790...38,023,369
Ensembl chr12:37,984,790...38,023,368
JBrowse link
G Vps37c VPS37C subunit of ESCRT-I ISO
IBA
(PMID:18005716), (PMID:22405001)
PMID:21873635
RGD PMID:18005716, PMID:22405001, PMID:21873635 RGD:13792537 NCBI chr 1:226,742,267...226,774,109
Ensembl chr 1:226,742,343...226,767,868
JBrowse link
G Vps37d VPS37D subunit of ESCRT-I ISO
IBA
(PMID:18005716), (PMID:22405001)
PMID:21873635
RGD PMID:18005716, PMID:22405001, PMID:21873635 RGD:13792537 NCBI chr12:24,651,342...24,656,793
Ensembl chr12:24,651,314...24,656,793
JBrowse link
ESCRT II complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snf8 SNF8 subunit of ESCRT-II ISO
IBA
(PMID:16973552)
PMID:21873635
RGD PMID:16973552, PMID:21873635 RGD:13792537 NCBI chr10:83,856,331...83,868,621
Ensembl chr10:83,856,280...83,868,598
JBrowse link
G Vps25 vacuolar protein sorting 25 homolog ISO
IBA
(PMID:16973552)
PMID:21873635
RGD PMID:16973552, PMID:21873635 RGD:13792537 NCBI chr10:89,174,684...89,180,165
Ensembl chr10:89,174,684...89,180,160
JBrowse link
G Vps36 vacuolar protein sorting 36 homolog IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:16973552)
Ensembl
RGD
PMID:16973552, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr16:74,719,642...74,743,921
Ensembl chr16:74,719,553...74,743,927
JBrowse link
ESCRT III complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp1a charged multivesicular body protein 1A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
JBrowse link
G Chmp1b charged multivesicular body protein 1B ISO (PMID:24878737) RGD PMID:24878737 NCBI chr18:62,923,620...62,926,150 JBrowse link
G Chmp2a charged multivesicular body protein 2A IBA
ISO
PMID:21873635
(PMID:18687924), (PMID:26040712)
RGD PMID:18687924, PMID:26040712, PMID:21873635 RGD:13792537 NCBI chr 1:65,540,808...65,543,708
Ensembl chr 1:65,541,322...65,543,707
JBrowse link
G Chmp2b charged multivesicular body protein 2B ISO
IBA
(PMID:24878737)
PMID:21873635
RGD PMID:24878737, PMID:21873635 RGD:13792537 NCBI chr11:2,666,405...2,692,213
Ensembl chr11:2,665,285...2,692,198
JBrowse link
G Chmp3 charged multivesicular body protein 3 IC
ISO
IBA
(PMID:18687924), (PMID:24878737)
PMID:21873635
RGD PMID:18687924, PMID:24878737, PMID:18076377, PMID:21873635 RGD:4892661, RGD:13792537 NCBI chr 4:99,449,213...99,496,156
Ensembl chr 4:99,449,111...99,494,423
JBrowse link
G Chmp4b charged multivesicular body protein 4B ISO
IBA
(PMID:18209100), (PMID:21310966), (PMID:21975012), (PMID:24878737), (PMID:26040712)
PMID:21873635
RGD PMID:18209100, PMID:21310966, PMID:21975012, PMID:24878737, PMID:26040712, PMID:21873635 RGD:13792537 NCBI chr 3:150,188,275...150,227,453
Ensembl chr 3:150,188,455...150,227,405
JBrowse link
G Chmp4bl1 chromatin modifying protein 4B-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:67,059,939...67,060,988
Ensembl chr 4:67,059,939...67,060,974
JBrowse link
G Chmp4c charged multivesicular body protein 4C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:93,574,554...93,641,497
Ensembl chr 2:93,574,559...93,641,497
JBrowse link
G Chmp6 charged multivesicular body protein 6 ISO
IBA
(PMID:24878737)
PMID:21873635
RGD PMID:24878737, PMID:21873635 RGD:13792537 NCBI chr10:109,073,678...109,079,348
Ensembl chr10:109,073,678...109,079,348
JBrowse link
G Chmp7 charged multivesicular body protein 7 ISO (PMID:16856878), (PMID:26040712) RGD PMID:16856878, PMID:26040712 NCBI chr15:51,385,373...51,400,606
Ensembl chr15:51,385,386...51,400,606
JBrowse link
G RGD1566265 similar to RIKEN cDNA 2610002M06 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:78,870,964...78,911,601
Ensembl chr  X:78,870,964...78,911,601
JBrowse link
ESCRT-0 complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate IEA
ISO
GO_REF:0000107
(PMID:24790097)
Ensembl
RGD
PMID:24790097 GO_REF:0000107 NCBI chr10:109,638,944...109,657,460
Ensembl chr10:109,638,767...109,657,456
JBrowse link
G Stam signal transducing adaptor molecule ISO
IBA
(PMID:24790097)
PMID:21873635
RGD PMID:24790097, PMID:21873635 RGD:13792537 NCBI chr17:81,209,795...81,256,111
Ensembl chr17:81,209,867...81,255,808
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      ESCRT complex 26
        ESCRT I complex 10
        ESCRT II complex 3
        ESCRT III complex 11
        ESCRT IV complex 0
        ESCRT-0 complex 2
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      organelle 13258
        membrane-bounded organelle 11449
          vesicle 2059
            intracellular vesicle 1900
              cytoplasmic vesicle 1894
                endosome 867
                  ESCRT complex 26
                    ESCRT I complex 10
                    ESCRT II complex 3
                    ESCRT III complex 11
                    ESCRT IV complex 0
                    ESCRT-0 complex 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.