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ONTOLOGY REPORT - ANNOTATIONS


Term:ESCRT complex
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Accession:GO:0036452 term browser browse the term
Definition:An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes.
Synonyms:exact_synonym: endosomal sorting complex required for transport
 xref: Wikipedia:ESCRT



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ESCRT I complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dennd4a DENN domain containing 4A part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:65,322,920...65,436,331
Ensembl chr 8:65,322,941...65,436,330
JBrowse link
G Diaph3 diaphanous-related formin 3 part_of IEA
ISO
GO_REF:0000107
(PMID:33036023)
Ensembl
RGD
PMID:33036023 GO_REF:0000107 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
JBrowse link
G Mvb12a multivesicular body subunit 12A part_of IEA
ISO
IBA
GO_REF:0000002
(PMID:18005716), (PMID:20654576), (PMID:22232651), (PMID:32424346)
GO_REF:0000033
GO_REF:0000107
InterPro
RGD
GO_Central
Ensembl
PMID:18005716 PMID:20654576 PMID:22232651 PMID:32424346 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr16:18,252,227...18,257,111
Ensembl chr16:18,252,222...18,257,539
JBrowse link
G Mvb12b multivesicular body subunit 12B part_of IBA
ISO
GO_REF:0000033
(PMID:18005716)
(PMID:20654576)
GO_Central
RGD
PMID:18005716 PMID:20654576 GO_REF:0000033 NCBI chr 3:17,034,002...17,192,658
Ensembl chr 3:17,034,003...17,193,202
JBrowse link
G Tsg101 tumor susceptibility 101 part_of ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:18005716), (PMID:20654576), (PMID:21757351), (PMID:22232651), (PMID:32424346)
UniProt
Ensembl
GO_Central
RGD
PMID:18005716 PMID:20654576 PMID:21757351 PMID:22232651 PMID:32424346 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554
JBrowse link
G Ubap1 ubiquitin-associated protein 1 part_of ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000002
(PMID:21757351)
UniProt
GO_Central
InterPro
RGD
PMID:21757351 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:56,520,722...56,561,153
Ensembl chr 5:56,520,743...56,561,152
JBrowse link
G Ubap1l ubiquitin associated protein 1-like part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:65,877,488...65,897,593
Ensembl chr 8:65,884,729...65,897,593
JBrowse link
G Uevld UEV and lactate/malate dehyrogenase domains part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:97,454,188...97,486,004
Ensembl chr 1:97,453,946...97,486,000
JBrowse link
G Vps28 VPS28 subunit of ESCRT-I part_of IEA
ISO
IBA
ISS
GO_REF:0000104
(PMID:18005716), (PMID:20654576), (PMID:21757351), (PMID:22232651), (PMID:32424346)
GO_REF:0000033
GO_REF:0000024
UniProt
RGD
GO_Central
PMID:18005716 PMID:20654576 PMID:21757351 PMID:22232651 PMID:32424346 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 7:108,341,989...108,345,837
Ensembl chr 7:108,341,989...108,345,837
JBrowse link
G Vps37a VPS37A subunit of ESCRT-I part_of ISO
IBA
(PMID:18005716), (PMID:20654576), (PMID:21757351)
GO_REF:0000033
RGD
GO_Central
PMID:18005716 PMID:20654576 PMID:21757351 GO_REF:0000033 NCBI chr16:51,736,170...51,775,384
Ensembl chr16:51,737,481...51,775,390
JBrowse link
G Vps37b VPS37B subunit of ESCRT-I part_of IBA
ISO
GO_REF:0000033
(PMID:18005716), (PMID:21757351), (PMID:22232651), (PMID:22405001), (PMID:32424346)
GO_Central
RGD
PMID:18005716 PMID:21757351 PMID:22232651 PMID:22405001 PMID:32424346 GO_REF:0000033 NCBI chr12:32,560,047...32,589,015
Ensembl chr12:32,560,047...32,589,014
JBrowse link
G Vps37c VPS37C subunit of ESCRT-I part_of IBA
ISO
GO_REF:0000033
(PMID:18005716), (PMID:21757351), (PMID:22405001)
GO_Central
RGD
PMID:18005716 PMID:21757351 PMID:22405001 GO_REF:0000033 NCBI chr 1:207,336,694...207,362,295
Ensembl chr 1:207,336,731...207,362,289
JBrowse link
G Vps37d VPS37D subunit of ESCRT-I part_of IBA
ISO
GO_REF:0000033
(PMID:18005716), (PMID:21757351), (PMID:22405001)
GO_Central
RGD
PMID:18005716 PMID:21757351 PMID:22405001 GO_REF:0000033 NCBI chr12:21,609,210...21,614,669
Ensembl chr12:21,609,182...21,614,659
JBrowse link
ESCRT II complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ramp2 receptor activity modifying protein 2 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Snf8 SNF8 subunit of ESCRT-II part_of IEA
ISO
IBA
GO_REF:0000104
(PMID:16973552), (PMID:18539118)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:16973552 PMID:18539118 GO_REF:0000033 GO_REF:0000104 NCBI chr10:80,984,337...80,996,724
Ensembl chr10:80,984,363...80,996,734
JBrowse link
G Vps25 vacuolar protein sorting 25 homolog part_of IEA
ISO
IBA
GO_REF:0000002
(PMID:16973552), (PMID:18539118)
GO_REF:0000033
InterPro
RGD
GO_Central
PMID:16973552 PMID:18539118 GO_REF:0000002 GO_REF:0000033 NCBI chr10:86,196,062...86,201,606
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Vps36 vacuolar protein sorting 36 homolog part_of IEA
ISO
IBA
GO_REF:0000104
(PMID:16973552), (PMID:18539118)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:16973552 PMID:18539118 GO_REF:0000033 GO_REF:0000104 NCBI chr16:69,810,404...69,834,789
Ensembl chr16:69,808,193...69,834,810
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
JBrowse link
ESCRT III complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp1a charged multivesicular body protein 1A part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:51,238,153...51,246,433
Ensembl chr19:51,238,160...51,246,436
JBrowse link
G Chmp1b charged multivesicular body protein 1B part_of ISO (PMID:24878737) RGD PMID:24878737 NCBI chr18:60,740,349...60,742,879 JBrowse link
G Chmp1b2 charged multivesicular body protein 1B2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:72,860,409...72,901,232
Ensembl chr  X:72,860,409...72,901,246
JBrowse link
G Chmp2a charged multivesicular body protein 2A part_of ISO
IBA
(PMID:18687924), (PMID:26040712)
GO_REF:0000033
RGD
GO_Central
PMID:18687924 PMID:26040712 GO_REF:0000033 NCBI chr 1:73,660,045...73,662,894
Ensembl chr 1:73,660,046...73,662,452
JBrowse link
G Chmp2b charged multivesicular body protein 2B part_of ISO
IBA
(PMID:24878737)
GO_REF:0000033
RGD
GO_Central
PMID:24878737 GO_REF:0000033 NCBI chr11:3,337,478...3,364,015
Ensembl chr11:3,337,494...3,385,181
JBrowse link
G Chmp3 charged multivesicular body protein 3 part_of IC
IBA
ISO
GO_REF:0000033
(PMID:18687924), (PMID:24878737)
GO_Central
RGD
PMID:18687924 PMID:24878737 PMID:18076377 GO_REF:0000033, RGD:4892661 NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959
JBrowse link
G Chmp4b charged multivesicular body protein 4B part_of ISO
IBA
(PMID:18209100), (PMID:21310966), (PMID:21975012), (PMID:24878737), (PMID:26040712)
GO_REF:0000033
RGD
GO_Central
PMID:18209100 PMID:21310966 PMID:21975012 PMID:24878737 PMID:26040712 GO_REF:0000033 NCBI chr 3:143,170,859...143,211,376
Ensembl chr 3:143,170,902...143,210,844
JBrowse link
G Chmp4bl1 chromatin modifying protein 4B-like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:68,049,742...68,050,791
Ensembl chr 4:68,049,705...68,050,676
JBrowse link
G Chmp4c charged multivesicular body protein 4C part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668
JBrowse link
G Chmp6 charged multivesicular body protein 6 part_of ISO
IBA
(PMID:24878737)
GO_REF:0000033
RGD
GO_Central
PMID:24878737 GO_REF:0000033 NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640
JBrowse link
G Chmp7 charged multivesicular body protein 7 part_of ISO
IBA
(PMID:16856878), (PMID:26040712)
GO_REF:0000033
RGD
GO_Central
PMID:16856878 PMID:26040712 GO_REF:0000033 NCBI chr15:44,790,983...44,806,216
Ensembl chr15:44,790,996...44,806,216
JBrowse link
ESCRT-0 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate part_of IEA
ISO
GO_REF:0000107
(PMID:19278655), (PMID:24790097)
Ensembl
RGD
PMID:19278655 PMID:24790097 GO_REF:0000107 NCBI chr10:105,739,617...105,757,838
Ensembl chr10:105,739,296...105,757,835
JBrowse link
G Stam signal transducing adaptor molecule part_of IBA
ISO
GO_REF:0000033
(PMID:19278655), (PMID:24790097)
GO_Central
RGD
PMID:19278655 PMID:24790097 GO_REF:0000033 NCBI chr17:77,120,235...77,166,173
Ensembl chr17:77,120,158...77,166,467
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20811
    protein-containing complex 6431
      ESCRT complex 31
        ESCRT I complex 13
        ESCRT II complex 5
        ESCRT III complex 11
        ESCRT IV complex 0
        ESCRT-0 complex 2
Path 2
Term Annotations click to browse term
  cellular_component 20811
    cellular anatomical entity 20571
      organelle 13997
        membrane-bounded organelle 12597
          vesicle 2241
            intracellular vesicle 2056
              cytoplasmic vesicle 2047
                endosome 948
                  ESCRT complex 31
                    ESCRT I complex 13
                    ESCRT II complex 5
                    ESCRT III complex 11
                    ESCRT IV complex 0
                    ESCRT-0 complex 2
paths to the root