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ONTOLOGY REPORT - ANNOTATIONS


Term:proteasome-activating activity
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Accession:GO:0036402 term browser browse the term
Definition:Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
Synonyms:exact_synonym: ATPase involved in positive regulation of proteasomal protein catabolic process;   proteasomal ATPase activity;   proteasome-activating ATPase activity
 narrow_synonym: proteasome channel gating activity;   proteasome channel opening activity
 xref: EC:5.6.1.5



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proteasome-activating activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psmc1 proteasome 26S subunit, ATPase 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 enables ISO
IEA
IBA
(PMID:9295362)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:9295362 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
JBrowse link

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  molecular_function 20623
    ATP-dependent activity 629
      proteasome-activating activity 6
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