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Term:proteasome-activating ATPase activity
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Accession:GO:0036402 term browser browse the term
Definition:Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
Synonyms:exact_synonym: ATPase involved in positive regulation of proteasomal protein catabolic process;   proteasomal ATPase activity
 narrow_synonym: proteasome channel gating activity;   proteasome channel opening activity

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proteasome-activating ATPase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psmc1 proteasome 26S subunit, ATPase 1 JBrowse link 6 124,123,283 124,135,644 RGD:13792537
G Psmc2 proteasome 26S subunit, ATPase 2 JBrowse link 4 9,867,132 9,881,383 RGD:1600115
G Psmc4 proteasome 26S subunit, ATPase 4 JBrowse link 1 84,978,220 84,986,536 RGD:1600115

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  molecular_function 18263
    catalytic activity 5790
      hydrolase activity 2515
        hydrolase activity, acting on acid anhydrides 826
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 824
            pyrophosphatase activity 822
              nucleoside-triphosphatase activity 767
                ATPase activity 429
                  ATPase activity, coupled 262
                    proteasome-activating ATPase activity 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.