ONTOLOGY REPORT - ANNOTATIONS
Term: transforming growth factor beta activation
Accession: GO:0036363
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Definition: The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms.
Synonyms: exact_synonym: L-TGF-beta activation; TGF-B activation; TGF-beta activation; TGFB activation; TGFbeta activation; latent TGF-beta activation
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LTBP3
latent transforming growth factor beta binding protein 3
involved_in
IMP
(PMID:18672106)
UniProt
PMID:18672106
NCBI chr11:65,538,559...65,558,359
Ensembl chr11:65,538,559...65,558,930
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ACVR2B
activin A receptor type 2B
involved_in
ISO
AgBase
DOI:10.1016/j.procbio.2011.10.027
NCBI chr 3:38,453,890...38,493,142
Ensembl chr 3:38,453,890...38,493,142
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HSP90AB1
heat shock protein 90 alpha family class B member 1
involved_in
IDA
(PMID:20599762)
UniProt
PMID:20599762
NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
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GATA6
GATA binding protein 6
involved_in
IDA
(PMID:33082341)
UniProt
PMID:33082341
NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
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TSC22D1
TSC22 domain family member 1
involved_in
IMP
(PMID:15881652)
UniProt
PMID:15881652
NCBI chr13:44,432,143...44,577,344
Ensembl chr13:44,432,143...44,577,147
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ADAM8
ADAM metallopeptidase domain 8
involved_in
ISS IEA
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868
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AGT
angiotensinogen
involved_in
ISS
UniProt
GO_REF:0000024
NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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ITGAV
integrin subunit alpha V
involved_in
IDA
(PMID:22278742)
UniProt
PMID:22278742
NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901
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ITGB6
integrin subunit beta 6
involved_in
IDA
(PMID:22278742)
UniProt
PMID:22278742
NCBI chr 2:160,099,671...160,200,272
Ensembl chr 2:160,099,667...160,200,313
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ITGB8
integrin subunit beta 8
involved_in
IEA ISS
Ensembl UniProt
GO_REF:0000024 GO_REF:0000107
NCBI chr 7:20,329,766...20,415,754
Ensembl chr 7:20,330,702...20,415,754
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LRRC32
leucine rich repeat containing 32
involved_in
IDA
(PMID:19651619), (PMID:19750484), (PMID:22278742)
UniProt
PMID:19651619 PMID:19750484 PMID:22278742
NCBI chr11:76,657,524...76,670,747
Ensembl chr11:76,657,524...76,670,747
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LTBP1
latent transforming growth factor beta binding protein 1
involved_in
IDA
(PMID:2022183), (PMID:8617200)
UniProt
PMID:2022183 PMID:8617200
NCBI chr 2:32,946,953...33,399,509
Ensembl chr 2:32,946,953...33,399,509
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LRRC32
leucine rich repeat containing 32
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr11:76,657,524...76,670,747
Ensembl chr11:76,657,524...76,670,747
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NRROS
negative regulator of reactive oxygen species
involved_in
ISS IBA IEA
UniProt GO_Central Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 3:196,639,694...196,662,004
Ensembl chr 3:196,639,694...196,662,004
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PSG9
pregnancy specific beta-1-glycoprotein 9
involved_in
IDA
(PMID:27389696)
UniProt
PMID:27389696
NCBI chr19:43,253,282...43,269,530
Ensembl chr19:43,211,791...43,269,530
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