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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:Fas signaling pathway
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Accession:GO:0036337 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.
Synonyms:exact_synonym: Apo-1 signaling pathway;   CD95 signaling pathway;   Fas receptor signaling pathway;   FasR signaling pathway
 narrow_synonym: FAS ligand-Fas signaling pathway;   Fas-FasL signaling pathway
 related_synonym: FasL signaling pathway

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show annotations for term's descendants           Sort by:
Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp8ap2 caspase 8 associated protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936510:2,420,924...2,447,634
Ensembl chrNW_004936510:2,420,920...2,447,986 		JBrowse link
G Faf1 Fas associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936522:9,774,943...10,160,987
Ensembl chrNW_004936522:9,784,203...10,161,774 		JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:11096076)
(PMID:12221075) 		CAFA
BHF-UCL		 PMID:11096076 PMID:12221075 NCBI chrNW_004936735:209,369...234,582 JBrowse link
negative regulation of Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad5 SMAD family member 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936597:3,225,374...3,264,604
Ensembl chrNW_004936597:3,225,374...3,264,604 		JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936569:803,154...820,000
Ensembl chrNW_004936569:800,760...820,271 		JBrowse link
regulation of Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:17245429) UniProt PMID:17245429 NCBI chrNW_004936525:6,136,343...6,231,051 JBrowse link
G Zdhhc7 zDHHC palmitoyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936641:3,175,338...3,199,487
Ensembl chrNW_004936641:3,175,338...3,199,484 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17413
    cellular process 17013
      signal transduction 5751
        cell surface receptor signaling pathway 2581
          Fas signaling pathway 7
            negative regulation of Fas signaling pathway 2
            positive regulation of Fas signaling pathway 0
            regulation of Fas signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 17413
    biological regulation 11398
      regulation of biological process 11034
        signaling 6245
          signal transduction 5751
            cell surface receptor signaling pathway 2581
              Fas signaling pathway 7
                negative regulation of Fas signaling pathway 2
                positive regulation of Fas signaling pathway 0
                regulation of Fas signaling pathway + 4
paths to the root