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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:Fas signaling pathway
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Accession:GO:0036337 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.
Synonyms:exact_synonym: Apo-1 signaling pathway;   CD95 signaling pathway;   Fas receptor signaling pathway;   FasR signaling pathway
 narrow_synonym: FAS ligand-Fas signaling pathway;   Fas-FasL signaling pathway
 related_synonym: FasL signaling pathway

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Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP8AP2 caspase 8 associated protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:14,586,857...14,632,384
Ensembl chr13:14,586,929...14,632,362 		JBrowse link
G FAF1 Fas associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:81,978,590...82,475,130
Ensembl chr20:81,978,966...82,477,842 		JBrowse link
negative regulation of Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD5 SMAD family member 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr23:38,877,294...38,926,208
Ensembl chr23:38,877,315...38,921,202 		JBrowse link
G TMBIM1 transmembrane BAX inhibitor motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:104,155,823...104,174,135
Ensembl chr10:104,155,185...104,163,793 		JBrowse link
regulation of Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SP100 SP100 nuclear antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:116,454,261...116,587,093
Ensembl chr10:116,459,050...116,590,215 		JBrowse link
G ZDHHC7 zDHHC palmitoyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,379,228...70,419,885
Ensembl chr 5:70,379,179...70,401,139 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19706
    cellular process 19211
      signal transduction 5673
        cell surface receptor signaling pathway 2811
          Fas signaling pathway 6
            negative regulation of Fas signaling pathway 2
            positive regulation of Fas signaling pathway 0
            regulation of Fas signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 19706
    biological regulation 12159
      regulation of biological process 11759
        signaling 6206
          signal transduction 5673
            cell surface receptor signaling pathway 2811
              Fas signaling pathway 6
                negative regulation of Fas signaling pathway 2
                positive regulation of Fas signaling pathway 0
                regulation of Fas signaling pathway + 4
paths to the root