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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:Fas signaling pathway
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Accession:GO:0036337 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.
Synonyms:exact_synonym: Apo-1 signaling pathway;   CD95 signaling pathway;   Fas receptor signaling pathway;   FasR signaling pathway
 narrow_synonym: FAS ligand-Fas signaling pathway;   Fas-FasL signaling pathway
 related_synonym: FasL signaling pathway


show annotations for term's descendants           Sort by:
Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP8AP2 caspase 8 associated protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:87,707,152...87,754,836
Ensembl chr 6:90,996,127...91,023,757 		JBrowse link
G FAF1 Fas associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,679,198...50,207,129
Ensembl chr 1:51,188,540...51,606,904 		JBrowse link
G FAS Fas cell surface death receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612 		JBrowse link
negative regulation of Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD5 SMAD family member 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:131,524,229...131,574,119
Ensembl chr 5:137,664,067...137,712,635 		JBrowse link
G TMBIM1 transmembrane BAX inhibitor motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:105,533,578...105,551,969
Ensembl chr2B:224,131,478...224,143,170 		JBrowse link
regulation of Fas signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SP100 SP100 nuclear antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:117,673,152...117,799,911
Ensembl chr2B:236,496,446...236,601,096 		JBrowse link
G ZDHHC7 zDHHC palmitoyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,643,906...65,681,301
Ensembl chr16:84,982,607...85,019,622 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18868
      signal transduction 5521
        cell surface receptor signaling pathway 2680
          Fas signaling pathway 7
            negative regulation of Fas signaling pathway 2
            positive regulation of Fas signaling pathway 0
            regulation of Fas signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 19315
    biological regulation 11857
      regulation of biological process 11476
        signaling 6031
          signal transduction 5521
            cell surface receptor signaling pathway 2680
              Fas signaling pathway 7
                negative regulation of Fas signaling pathway 2
                positive regulation of Fas signaling pathway 0
                regulation of Fas signaling pathway + 4
paths to the root