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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor receptor-2 signaling pathway
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Accession:GO:0036324 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-2 (VEGFR-2) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: FLK-1 signaling pathway;   KDR signaling pathway;   VEGFR-2 signaling pathway;   VEGFR2 signaling pathway



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vascular endothelial growth factor receptor-2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec14a C-type lectin domain containing 14A involved_in
acts_upstream_of_or_within_negative_effect
ISO (PMID:27991863)
MGI:6404416 (MGI:5881854|PMID:27991863)
RGD PMID:27991863 MGI:5881854 NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3831615|PMID:19033661)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19033661 GO_REF:0000024 GO_REF:0000107 MGI:3831615 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Kdr kinase insert domain receptor involved_in ISO
IEA
(PMID:24205206)
GO_REF:0000107
RGD
Ensembl
PMID:24205206 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Pdcd6 programmed cell death 6 involved_in ISO (PMID:21893193) RGD PMID:21893193 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189
JBrowse link
G Slc31a1 solute carrier family 31 member 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:35027734)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:35027734 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA
(PMID:23688497)
GO_REF:0000107
RGD
Ensembl
PMID:23688497 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18766
      signal transduction 7171
        cell surface receptor signaling pathway 2878
          enzyme-linked receptor protein signaling pathway 1049
            cell surface receptor protein tyrosine kinase signaling pathway 663
              vascular endothelial growth factor receptor signaling pathway 51
                vascular endothelial growth factor receptor-2 signaling pathway 6
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13616
      regulation of biological process 13210
        signaling 7723
          signal transduction 7171
            cell surface receptor signaling pathway 2878
              enzyme-linked receptor protein signaling pathway 1049
                cell surface receptor protein tyrosine kinase signaling pathway 663
                  vascular endothelial growth factor receptor signaling pathway 51
                    vascular endothelial growth factor receptor-2 signaling pathway 6
paths to the root