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ONTOLOGY REPORT - ANNOTATIONS


Term:response to sterol
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Accession:GO:0036314 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.


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cellular response to cholesterol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase IEP 25-hydroxycholesterol RGD PMID:3663886 RGD:2326225 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 IEP RGD PMID:15907796, PMID:17526932 RGD:1598535, RGD:2308820 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Apoe apolipoprotein E IEP RGD PMID:21169230 RGD:6904144 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Ces1d carboxylesterase 1D ISO (PMID:18762277) RGD PMID:18762277 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 IDA PMID:1694852 UniProt PMID:1694852 RGD:70534 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dag1 dystroglycan 1 IEP RGD PMID:22613990 RGD:11541063 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17761367)
Ensembl
UniProt
RGD
PMID:17761367 GO_REF:0000024, GO_REF:0000107 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Gramd1a GRAM domain containing 1A ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:6242147|PMID:30220461)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30220461 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6242147 NCBI chr 1:89,563,982...89,590,406
Ensembl chr 1:89,563,976...89,590,490
JBrowse link
G Gramd1b GRAM domain containing 1B ISO (MGI:MGI:6242147|PMID:30220461) RGD PMID:30220461 MGI:MGI:6242147 NCBI chr 8:44,160,634...44,399,110
Ensembl chr 8:44,165,367...44,327,551
JBrowse link
G Gramd1c GRAM domain containing 1C ISO (MGI:MGI:6242147|PMID:30220461) RGD PMID:30220461 MGI:MGI:6242147 NCBI chr11:61,609,370...61,659,355
NCBI chr11:62,580,983...62,634,961
Ensembl chr11:61,605,937...62,634,803
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IEP 24S-hydroxycholesterol RGD PMID:18303831 RGD:2326114 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Inhba inhibin subunit beta A IDA PMID:19464342 UniProt PMID:19464342 RGD:8554083 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inhbb inhibin subunit beta B IDA PMID:19464342 UniProt PMID:19464342 RGD:8554083 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G Lrp6 LDL receptor related protein 6 ISO (PMID:16890161) RGD PMID:16890161 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Lrp8 LDL receptor related protein 8 IEP RGD PMID:19414061 RGD:2324627 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
JBrowse link
G Mlc1 modulator of VRAC current 1 IDA PMID:19931615 UniProt PMID:19931615 RGD:2326037 NCBI chr 7:129,949,984...129,970,314
Ensembl chr 7:129,949,967...129,970,550
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 ISO MGI:MGI:6101514 (MGI:MGI:6101031|PMID:29149604) RGD PMID:29149604 MGI:MGI:6101031 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Osbpl7 oxysterol binding protein-like 7 ISO (PMID:21669198) RGD PMID:21669198 NCBI chr10:84,986,330...85,003,947
Ensembl chr10:84,986,328...85,004,562
JBrowse link
G Ptch1 patched 1 ISO (PMID:11278759)
(PMID:21931618)
RGD PMID:11278759, PMID:21931618 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Scp2 sterol carrier protein 2 IEP RGD PMID:8847489, PMID:7989577 RGD:9850161, RGD:9850255 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Smo smoothened, frizzled class receptor ISO
IEA
(PMID:21931618)
GO_REF:0000107
RGD
Ensembl
PMID:21931618 GO_REF:0000107 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
cellular response to ergosterol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dynap dynactin associated protein ISO (PMID:20978158) RGD PMID:20978158 NCBI chr18:68,752,224...68,755,426
Ensembl chr18:68,752,227...68,755,426
JBrowse link
cellular response to sterol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Insig1 insulin induced gene 1 ISO (PMID:12202038) RGD PMID:12202038 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Rora RAR-related orphan receptor A ISO (PMID:18658046), (PMID:19965867) RGD PMID:18658046, PMID:19965867 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rorc RAR-related orphan receptor C ISO (PMID:19965867) RGD PMID:19965867 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
response to cholesterol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 IEA
ISO
GO_REF:0000107
(PMID:11178988)
Ensembl
RGD
PMID:11178988 GO_REF:0000107 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant IEP RGD PMID:19110235 RGD:2315908 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 IEP RGD PMID:9722683 RGD:69375 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO
ISS
(PMID:19523456)
GO_REF:0000024
RGD
UniProt
PMID:19523456 GO_REF:0000024 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP RGD PMID:20435353 RGD:4889907 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEA
ISO
GO_REF:0000107
(PMID:19523456)
Ensembl
RGD
PMID:19523456 GO_REF:0000107 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 IEP RGD PMID:25263431 RGD:15045610 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G F7 coagulation factor VII IDA RGD PMID:15670042 RGD:11049546 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fdps farnesyl diphosphate synthase IEP RGD PMID:2909544 RGD:2316308 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IEP RGD PMID:25263431 RGD:15045610 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IEP RGD PMID:2903839 RGD:2326164 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 IEP RGD PMID:25263431 RGD:15045610 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IEP RGD PMID:25263431 RGD:15045610 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Pmvk phosphomevalonate kinase ISO (PMID:10191291) RGD PMID:10191291 NCBI chr 2:188,784,329...188,793,890
Ensembl chr 2:188,784,222...188,793,895
JBrowse link
G Smad2 SMAD family member 2 ISO (PMID:17878231) RGD PMID:17878231 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
ISS
(PMID:17878231)
GO_REF:0000024
RGD
UniProt
PMID:17878231 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO (PMID:17878231)
(MGI:MGI:3766844|PMID:17878231)
RGD PMID:17878231 MGI:MGI:3766844 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO (MGI:MGI:3766844|PMID:17878231)
(PMID:17878231)
RGD PMID:17878231 MGI:MGI:3766844 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
SREBP-SCAP complex retention in endoplasmic reticulum term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07060293.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:66,336,143...66,336,901 JBrowse link
G Insig1 insulin induced gene 1 IBA
ISO
PMID:21873635
(PMID:12202038), (PMID:32322062)
RGD PMID:12202038, PMID:32322062, PMID:21873635 RGD:13792537 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:32322062)
UniProt
RGD
PMID:32322062, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to chemical 6342
        response to oxygen-containing compound 2344
          response to sterol 44
            cellular response to sterol + 27
            response to cholesterol + 38
            response to diosgenin + 0
            response to ecdysone + 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to chemical 6342
        response to organic substance 3865
          response to organic cyclic compound 1453
            response to sterol 44
              cellular response to sterol + 27
              response to cholesterol + 38
              response to diosgenin + 0
              response to ecdysone + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.