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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:lymph vessel morphogenesis
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Accession:GO:0036303 term browser browse the term
Definition:The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.



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lymph vessel morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting acts_upstream_of_or_within ISO MGI:3612341 (MGI:5576424|PMID:24767999) RGD PMID:24767999 MGI:5576424 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
MGI:5286317|MGI:6188639 (MGI:5913245|PMID:28179432), (MGI:6156694|PMID:28179430)
Ensembl
RGD
PMID:28179430 PMID:28179432 PMID:21873635 GO_REF:0000107 MGI:5913245 MGI:6156694, RGD:13792537 NCBI chr 5:72,811,200...72,988,185
Ensembl chr 5:72,811,410...72,988,525
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:4461879|PMID:18093989) RGD PMID:18093989 MGI:4461879 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
branching involved in lymph vessel morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (MGI:3848105|PMID:19233265) RGD PMID:19233265 MGI:3848105 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 involved_in ISO (MGI:4439415|PMID:20223757) RGD PMID:20223757 MGI:4439415 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592
JBrowse link
lymphangiogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B involved_in ISO
IEA
(MGI:4436974|PMID:19903896)
GO_REF:0000107
RGD
Ensembl
PMID:19903896 GO_REF:0000107 MGI:4436974 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Acvrl1 activin A receptor like type 1 involved_in ISO (MGI:4436974|PMID:19903896) RGD PMID:19903896 MGI:4436974 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:4436974|PMID:19903896) RGD PMID:19903896 MGI:4436974 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 involved_in
acts_upstream_of_or_within
ISO (PMID:19935664)
MGI:5007046 (MGI:5432672|PMID:21778431)
RGD PMID:19935664 PMID:21778431 MGI:5432672 NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400
JBrowse link
G Clec14a C-type lectin domain containing 14A acts_upstream_of_or_within ISO MGI:6404416 (MGI:5881854|PMID:27991863) RGD PMID:27991863 MGI:5881854 NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5294901|PMID:20697430)
GO_REF:0000024
(PMID:19779139)
Ensembl
RGD
UniProt
PMID:19779139 PMID:20697430 GO_REF:0000024 GO_REF:0000107 MGI:5294901 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
JBrowse link
G Foxc2 forkhead box C2 involved_in ISO (PMID:12114478) RGD PMID:12114478 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:103178|MGI:107163 (MGI:3848105|PMID:19233265) RGD PMID:19233265 MGI:3848105 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Pdpn podoplanin involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2657021 (MGI:3522394|PMID:12853470)
UniProt
RGD
PMID:12853470 GO_REF:0000024 MGI:3522394 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta acts_upstream_of_or_within ISO MGI:102469|MGI:103178 (MGI:3848104|PMID:19233846) RGD PMID:19233846 MGI:3848104 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:12412020) RGD PMID:12412020 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
G Ptpn14 protein tyrosine phosphatase, non-receptor type 14 involved_in IBA
ISO
PMID:21873635
(MGI:4939987|PMID:20826270)
(PMID:20826270)
RGD PMID:20826270 PMID:21873635 MGI:4939987, RGD:13792537 NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088
JBrowse link
G Sox18 SRY-box transcription factor 18 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2178809 (MGI:3828192|PMID:18931657)
(PMID:12740761)
RGD PMID:12740761 PMID:18931657 PMID:21873635 MGI:3828192, RGD:13792537 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290
JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within ISO MGI:102469|MGI:107163 (MGI:3848105|PMID:19233265)
(MGI:4439256|PMID:20133819)
RGD PMID:19233265 PMID:20133819 MGI:3848105 MGI:4439256 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
lymphatic endothelial cell migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccbe1 collagen and calcium binding EGF domains 1 acts_upstream_of ISO MGI:5007046 (MGI:5432672|PMID:21778431) RGD PMID:21778431 MGI:5432672 NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400
JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of ISO (MGI:3654815|PMID:16291864) RGD PMID:16291864 MGI:3654815 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Lgals8 galectin 8 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:19268462)
PMID:21873635
UniProt
RGD
PMID:19268462 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
JBrowse link
negative regulation of lymphangiogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epha2 Eph receptor A2 acts_upstream_of_or_within ISO MGI:3040415 (MGI:3847147|PMID:19443703) RGD PMID:19443703 MGI:3847147 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (MGI:5314489|PMID:22171010) RGD PMID:22171010 MGI:5314489 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Vash1 vasohibin 1 acts_upstream_of_or_within ISO UniProtKB:P97953|UniProtKB:Q00731 (PMID:20133819) RGD PMID:20133819 NCBI chr 6:106,330,374...106,345,740
Ensembl chr 6:106,329,123...106,345,726
JBrowse link
positive regulation of lymphangiogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccbe1 collagen and calcium binding EGF domains 1 involved_in ISO (MGI:5568630|PMID:24552833) RGD PMID:24552833 MGI:5568630 NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400
JBrowse link
G Mir9-3 microRNA 9-3 acts_upstream_of ISO (PMID:26354749) RGD PMID:26354749 NCBI chr 1:133,440,049...133,440,138 JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within ISO (MGI:4439256|PMID:20133819) RGD PMID:20133819 MGI:4439256 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfc vascular endothelial growth factor C acts_upstream_of_or_within
involved_in
ISO (MGI:4439256|PMID:20133819)
(MGI:5568630|PMID:24552833)
RGD PMID:20133819 PMID:24552833 MGI:4439256 MGI:5568630 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    developmental process 6909
      anatomical structure morphogenesis 2939
        lymph vessel morphogenesis 24
          lymphangiogenesis + 20
          lymphatic endothelial cell migration 3
Path 2
Term Annotations click to browse term
  biological_process 19553
    developmental process 6909
      anatomical structure development 6435
        multicellular organism development 5184
          system development 4463
            circulatory system development 1359
              vasculature development 888
                lymph vessel development 32
                  lymph vessel morphogenesis 24
                    lymphangiogenesis + 20
                    lymphatic endothelial cell migration 3
paths to the root