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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to decreased oxygen levels
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Accession:GO:0036294 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
Comment:This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'cellular response to hypoxia ; GO:0071456'.
Synonyms:exact_synonym: cellular response to lowered oxygen levels


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cellular response to decreased oxygen levels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 acts_upstream_of_or_within ISO (PMID:24875179) MGI PMID:24875179
G CPEB4 cytoplasmic polyadenylation element binding protein 4 involved_in ISO PMID:20937770 UniProt PMID:20937770 RGD:8553637 NCBI chr16:50,430,345...50,499,086
Ensembl chr16:50,430,348...50,498,938 		JBrowse link
G MIR142 microRNA mir-142 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr12:34,609,378...34,609,457
Ensembl chr12:34,609,364...34,609,468 		JBrowse link
G MIR150-1 microRNA mir-150-1 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr 6:54,580,912...54,580,988
Ensembl chr 6:54,580,912...54,580,988 		JBrowse link
G MIR15B microRNA mir-15b acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr13:100,083,172...100,083,269
Ensembl chr13:100,083,172...100,083,269 		JBrowse link
G MIR17 microRNA mir-17 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr11:60,734,656...60,734,732
Ensembl chr11:60,734,656...60,734,732 		JBrowse link
G MIR199A-1 microRNA mir-199a-1 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr 9:114,533,783...114,533,858
Ensembl chr 9:114,533,777...114,533,880 		JBrowse link
G MIR199A-2 microRNA mir-199a-2 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr 2:69,558,051...69,558,130
Ensembl chr 2:69,558,050...69,558,131 		JBrowse link
G MIR199B microRNA mir-199b acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr 1:268,691,520...268,691,593
Ensembl chr 1:268,691,502...268,691,610 		JBrowse link
G MIR204 microRNA mir-204 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr 1:224,065,494...224,065,602
Ensembl chr 1:224,065,494...224,065,602 		JBrowse link
G MIR20B-1 microRNA mir-20b-1 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr  X:110,113,980...110,114,059
Ensembl chr  X:110,113,980...110,114,059 		JBrowse link
G MIR21 microRNA mir-21 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358 		JBrowse link
G MIR221 microRNA mir-221 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr  X:40,571,068...40,571,137
Ensembl chr  X:40,571,068...40,571,137 		JBrowse link
G MIR222 microRNA mir-222 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr  X:40,571,808...40,571,887
Ensembl chr  X:40,571,808...40,571,887 		JBrowse link
G MIR31 microRNA mir-31 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr 1:201,198,732...201,198,809
Ensembl chr 1:201,198,732...201,198,809 		JBrowse link
G MIR491 microRNA mir-491 acts_upstream_of_or_within ISO (PMID:19147652) MGI PMID:19147652 NCBI chr 1:202,227,251...202,227,326
Ensembl chr 1:202,227,236...202,227,336 		JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in ISO PMID:23843614 UniProt PMID:23843614 RGD:8553949 NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,451...9,825,539 		JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:24875179) MGI PMID:24875179 NCBI chr14:99,929,590...100,021,619 JBrowse link
G TSC1 TSC complex subunit 1 involved_in ISO PMID:23435171 ParkinsonsUK-UCL PMID:23435171 RGD:10448950 NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,951 		JBrowse link
cellular response to anoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:14975182 RGD:1599599 NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950 		JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase ISO RGD PMID:12194824 RGD:8553742 NCBI chr 3:23,887,120...23,980,231
Ensembl chr 3:23,887,125...23,956,373 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:18614764 RGD:2301848 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G PDCD10 programmed cell death 10 ISO RGD PMID:22482882 RGD:401827112 NCBI chr13:106,517,408...106,558,959
Ensembl chr13:106,517,432...106,558,895 		JBrowse link
cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAA2 acetyl-CoA acyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:99,284,467...99,310,759
Ensembl chr 1:99,284,140...99,311,321 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:141,221,177...141,233,728
Ensembl chr14:141,221,198...141,232,306 		JBrowse link
G ADO 2-aminoethanethiol dioxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:66,277,224...66,281,964
Ensembl chr14:66,277,947...66,278,759 		JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:19098126 RGD:8548506 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,033,579...150,040,731 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO oxygen-glucose deprivation RGD PMID:14526224 RGD:10047409 NCBI chr  X:106,676,596...106,708,290
Ensembl chr  X:106,670,520...106,708,317 		JBrowse link
G AK4 adenylate kinase 4 acts_upstream_of
involved_in		 ISO (PMID:19130895), (PMID:23474458), (PMID:26980435)
(PMID:30696468)		 UniProt PMID:19130895 PMID:23474458 PMID:26980435 PMID:30696468 NCBI chr 6:147,177,029...147,257,799
Ensembl chr 6:147,177,029...147,257,814 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:20515660 RGD:5509097
G ANGPT4 angiopoietin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,345,926...34,394,977
Ensembl chr17:34,348,556...34,402,851 		JBrowse link
G ANKRD1 ankyrin repeat domain 1 ISO RGD PMID:19299913 RGD:5133278 NCBI chr14:102,603,777...102,612,857
Ensembl chr14:102,603,777...102,612,839 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746 		JBrowse link
G AQP3 aquaporin 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24462679) MGI
Ensembl		 PMID:24462679 GO_REF:0000107 NCBI chr10:33,045,374...33,050,285
Ensembl chr10:33,045,245...33,051,082 		JBrowse link
G ASL argininosuccinate lyase ISO RGD PMID:11097477 RGD:1599264 NCBI chr 3:16,637,481...16,646,869
Ensembl chr 3:16,637,481...16,646,867 		JBrowse link
G ATF4 activating transcription factor 4 ISO oxygen-glucose deprivation RGD PMID:20444431 RGD:13464322 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b ISO RGD PMID:29300489 RGD:13792656 NCBI chr 4:108,896,063...108,907,626
Ensembl chr 4:108,896,057...108,907,805 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:21346155 RGD:11341705 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G B3GAT1 beta-1,3-glucuronyltransferase 1 ISO RGD PMID:21400481 RGD:14390075 NCBI chr 9:60,995,280...61,020,300
Ensembl chr 9:60,995,283...61,010,471 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G BBC3 BCL2 binding component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,046,887 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7595537)
with serum deprivation		 Ensembl
MGI
RGD		 PMID:7595537 PMID:20669351 GO_REF:0000107 RGD:11353793 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BCL2L1 BCL2 like 1 ISO with serum deprivation RGD PMID:20669351 RGD:11353793 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:19565561 RGD:4891057 NCBI chr 7:117,438,622...117,472,005
Ensembl chr 7:117,438,713...117,472,005 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:20436456)
(PMID:19273585)		 RGD
BHF-UCL
MGI		 PMID:17379825 PMID:19273585 PMID:20436456 RGD:9685412 NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,907 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19273585) MGI
Ensembl		 PMID:19273585 GO_REF:0000107 NCBI chr14:10,318,688...10,345,689
Ensembl chr14:10,318,732...10,345,679 		JBrowse link
G BRIP1 BRCA1 interacting helicase 1 ISO RGD PMID:12511571 RGD:11251702 NCBI chr12:36,498,138...36,639,847
Ensembl chr12:36,498,205...36,635,973 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO oxygen-glucose deprivation RGD PMID:23421680 RGD:13514095 NCBI chr 5:14,875,524...14,888,224
Ensembl chr 5:14,874,465...14,888,223 		JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:21073657 RGD:7206834 NCBI chr13:138,279,785...138,364,934
Ensembl chr13:138,280,364...138,364,252 		JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:29069575 RGD:151347449 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G CBL Cbl proto-oncogene ISO oxygen-glucose deprivation RGD PMID:24229686 RGD:11038824 NCBI chr 9:46,416,937...46,512,855
Ensembl chr 9:46,416,938...46,512,834 		JBrowse link
G CBS cystathionine beta-synthase involved_in ISO PMID:20149843 UniProt PMID:20149843 RGD:8554341 NCBI chr13:206,205,942...206,231,363
Ensembl chr13:206,205,946...206,230,248 		JBrowse link
G CCN1 cellular communication network factor 1 ISO RGD PMID:30371213 RGD:329845516 NCBI chr 4:130,392,404...130,395,179
Ensembl chr 4:130,392,407...130,395,150 		JBrowse link
G CCNA2 cyclin A2 ISO RGD PMID:25289051 RGD:10054493 NCBI chr 8:102,260,346...102,266,274
Ensembl chr 8:102,260,215...102,266,309 		JBrowse link
G CCNB1 cyclin B1 ISO RGD PMID:12374461 RGD:2316579 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:28854428 RGD:152025191 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:12031707 RGD:8663470 NCBI chr15:104,780,744...104,835,631
Ensembl chr15:104,781,616...104,835,630 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:25,155,652...25,158,517
Ensembl chr 1:25,155,664...25,160,279 		JBrowse link
G CLCA1 chloride channel accessory 1 ISO RGD PMID:18616988 RGD:4188872 NCBI chr 4:129,621,259...129,655,385
Ensembl chr 4:129,620,874...129,655,385 		JBrowse link
G COX4I2 cytochrome c oxidase subunit 4I2 ISO RGD PMID:23303788 RGD:11344908 NCBI chr17:35,340,499...35,346,090
Ensembl chr17:35,341,889...35,346,090 		JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO (PMID:18752464)
(MGI:5543770|PMID:18752464)		 UniProt PMID:18752464 MGI:5543770 NCBI chr 7:52,329,054...52,382,408
Ensembl chr 7:52,304,472...52,383,732 		JBrowse link
G CPEB2 cytoplasmic polyadenylation element binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,401,350...10,472,141
Ensembl chr 8:10,401,350...10,472,136 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 ISO oxygen-glucose deprivation RGD PMID:17910051 RGD:5144007 NCBI chr  X:62,380,778...62,407,736
Ensembl chr  X:62,380,780...62,456,689 		JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO oxygen-glucose deprivation RGD PMID:17910051 RGD:5144007 NCBI chr11:18,988,665...19,011,015
Ensembl chr11:18,987,174...19,011,015 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:18664364 RGD:150429768 NCBI chr 4:87,749,738...87,911,818
Ensembl chr 4:87,756,168...87,911,296 		JBrowse link
G DICER1 dicer 1, ribonuclease III ISO oxygen-glucose deprivation RGD PMID:26294080 RGD:11553310 NCBI chr 7:116,361,630...116,436,471
Ensembl chr 7:116,365,802...116,411,224 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 ISO oxygen-glucose deprivation RGD PMID:30653356 RGD:155663383 NCBI chr 1:130,376,720...130,386,411
Ensembl chr 1:130,376,721...130,386,411 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO RGD PMID:24282625 RGD:9589039 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087 		JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:20969567 RGD:7248614 NCBI chr16:49,189,555...49,193,722
Ensembl chr16:49,189,602...49,191,976 		JBrowse link
G E2F1 E2F transcription factor 1 ISO RGD PMID:19088195 RGD:2316261 NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,599...37,189,883 		JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:9551744 RGD:8662285 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:59,113,527...59,168,421
Ensembl chr14:59,113,844...59,168,395 		JBrowse link
G EGLN2 egl-9 family hypoxia inducible factor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:49,002,266...49,010,042 JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:65,805,513...65,833,536
Ensembl chr 7:65,805,522...65,833,529 		JBrowse link
G EGR1 early growth response 1 ISO RGD PMID:21220915 RGD:5131857 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 ISO RGD PMID:10100614 RGD:10401146 NCBI chr15:48,423,001...48,443,373
Ensembl chr15:48,422,816...48,443,399 		JBrowse link
G ELN elastin ISO RGD PMID:16055482 RGD:9585727 NCBI chr 3:11,214,194...11,245,891
Ensembl chr 3:11,214,205...11,244,897 		JBrowse link
G ENDOG endonuclease G ISO RGD PMID:17379825 RGD:9685412 NCBI chr 1:269,153,955...269,157,789
Ensembl chr 1:269,154,090...269,157,788 		JBrowse link
G ENO1 enolase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central
Ensembl		 PMID:12099714 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:11041576 NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,816...94,254,079 		JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha ISO RGD PMID:12752442 RGD:10401130 NCBI chr 1:182,268,651...182,318,147
Ensembl chr 1:182,265,261...182,318,195 		JBrowse link
G FABP1 fatty acid binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:57,850,511...57,854,966
Ensembl chr 3:57,850,499...57,854,956 		JBrowse link
G FAM162A family with sequence similarity 162 member A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:138,115,499...138,151,828
Ensembl chr13:138,115,509...138,151,738 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:12031707 RGD:8663470 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 ISO oxygen-glucose deprivation RGD PMID:23658809 RGD:12738215 NCBI chr 5:41,571,054...41,636,058
Ensembl chr 5:41,570,282...41,636,028 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO RGD PMID:31093967 RGD:155882597 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:11981751 RGD:634296 NCBI chr11:5,620,698...5,797,095
Ensembl chr11:5,621,212...5,795,264 		JBrowse link
G FMN2 formin 2 involved_in ISO (PMID:23375502) UniProt PMID:23375502
G FNDC1 fibronectin type III domain containing 1 acts_upstream_of_or_within ISO PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 1:8,007,320...8,106,875
Ensembl chr 1:8,007,321...8,081,817 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8593588 RGD:151347626 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G FOXO3 forkhead box O3 ISO RGD PMID:24278276 RGD:10402204 NCBI chr 1:74,626,673...74,760,323
Ensembl chr 1:74,628,218...74,760,325 		JBrowse link
G FXN frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chr 1:222,412,485...222,433,224
Ensembl chr 1:222,412,509...222,454,776 		JBrowse link
G GAD1 glutamate decarboxylase 1 ISO RGD PMID:11259512 RGD:401900595 NCBI chr15:76,991,863...77,034,819
Ensembl chr15:76,991,928...77,034,812 		JBrowse link
G GAD2 glutamate decarboxylase 2 ISO RGD PMID:11259512 RGD:401900595 NCBI chr10:49,316,682...49,391,013
Ensembl chr10:49,313,647...49,390,926 		JBrowse link
G GATA6 GATA binding protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:107,282,709...107,314,725
Ensembl chr 6:107,282,849...107,314,626 		JBrowse link
G GNB1 G protein subunit beta 1 acts_upstream_of_or_within ISO PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 6:63,867,155...63,957,514
Ensembl chr 6:63,867,158...63,952,505 		JBrowse link
G GNGT1 G protein subunit gamma transducin 1 acts_upstream_of_or_within ISO PMID:19723622 MGI PMID:19723622 RGD:8554041 NCBI chr 9:73,403,647...73,717,746
Ensembl chr 9:73,403,740...73,719,161 		JBrowse link
G GP91-PHOX NADPH oxidase heavy chain subunit ISO RGD PMID:21302291 RGD:11040609 NCBI chr  X:33,654,656...33,678,346
Ensembl chr  X:33,643,648...33,680,580 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:24011070) RGD
MGI
GO_Central
TreeGrafter
Ensembl		 PMID:18248612 PMID:19220706 PMID:24011070 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:9068456 RGD:9068884 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G HIF3A hypoxia inducible factor 3 subunit alpha NOT|involved_in ISO
IBA
IEA		 (PMID:11573933) UniProt
GO_Central
TreeGrafter		 PMID:11573933 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:52,342,893...52,376,339
Ensembl chr 6:52,342,885...52,373,058 		JBrowse link
G HIGD1A HIG1 hypoxia inducible domain family member 1A acts_upstream_of_or_within ISO (PMID:25683712)
(PMID:16815968), (PMID:21856340)		 MGI PMID:16815968 PMID:21856340 PMID:25683712 NCBI chr13:26,278,202...26,286,334
Ensembl chr13:26,278,208...26,286,202 		JBrowse link
G HILPDA hypoxia inducible lipid droplet associated involved_in ISO (PMID:10690527) UniProt PMID:10690527 NCBI chr18:19,944,929...19,947,080
Ensembl chr18:19,944,930...19,947,080 		JBrowse link
G HMOX1 heme oxygenase 1 involved_in IEA Ensembl GO_REF:0000107
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:24177414 RGD:10445837 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,500 		JBrowse link
G HP1BP3 heterochromatin protein 1 binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:78,975,551...79,007,921
Ensembl chr 6:78,975,555...79,007,889 		JBrowse link
G HYOU1 hypoxia up-regulated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:46,264,929...46,277,056
Ensembl chr 9:46,264,933...46,276,995 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:20631551 RGD:8662392 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G IL7 interleukin 7 ISO RGD PMID:19055876 RGD:10402937 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709 		JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:30765322 RGD:329849112 NCBI chr12:53,115,379...53,117,128
NCBI chr18:52,889,684...52,909,260
Ensembl chr18:52,889,684...52,900,967 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO RGD PMID:15793310 RGD:1579809 NCBI chr  X:124,717,604...124,724,855
Ensembl chr  X:124,717,612...124,724,860 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO oxygen-glucose deprivation RGD PMID:16135072 PMID:22159112 RGD:12904046 RGD:6893269 NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,478,706...47,529,242 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:17285299 RGD:6482794 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,912 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 ISO RGD PMID:17285299 RGD:6482794 NCBI chr 5:46,935,923...47,465,681
Ensembl chr 5:46,935,932...47,464,125 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8593588 RGD:151347626 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8593588 RGD:151347626 NCBI chr 2:66,214,086...66,219,435
Ensembl chr 2:66,214,138...66,217,002 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:8593588 RGD:151347626 NCBI chr 2:59,530,991...59,532,846 JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 involved_in ISO PMID:25352783 UniProt PMID:25352783 RGD:10047379 NCBI chr18:26,139,457...26,624,210
Ensembl chr18:26,139,457...26,623,233 		JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:24705172 RGD:9831164 NCBI chr 9:128,429,232...128,659,662
Ensembl chr 9:128,429,092...128,661,639 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 ISO RGD PMID:12215606 RGD:2316539 NCBI chr 3:112,322,446...112,359,212
Ensembl chr 3:112,322,446...112,359,212 		JBrowse link
G KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 ISO RGD PMID:19461047 RGD:10412041 NCBI chr16:53,616,532...53,631,197
Ensembl chr16:53,618,603...53,631,195 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:26439051 RGD:401794572 NCBI chr 6:50,580,016...50,593,518
Ensembl chr 6:50,580,022...50,593,544 		JBrowse link
G KDM6A lysine demethylase 6A ISO RGD PMID:30887465 RGD:151665136 NCBI chr  X:39,953,764...40,154,197
Ensembl chr  X:39,953,814...40,154,029 		JBrowse link
G LCN2 lipocalin 2 ISO oxygen-glucose deprivation RGD PMID:24916903 RGD:126790489 NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644 		JBrowse link
G LMNA lamin A/C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:93,899,019...93,927,255
Ensembl chr 4:93,899,019...93,926,320 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO oxygen-glucose deprivation RGD PMID:32734729 RGD:155804275 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:33,105,717...33,137,602
Ensembl chr 5:33,105,759...33,137,739 		JBrowse link
G MDM4 MDM4 regulator of p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:65,175,488...65,219,747
Ensembl chr 9:65,175,377...65,219,742 		JBrowse link
G MFN1 mitofusin 1 ISO oxygen-glucose deprivation RGD PMID:23658809 PMID:27833818 RGD:12738215 RGD:12910766 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481 		JBrowse link
G MFN2 mitofusin 2 ISO oxygen-glucose deprivation RGD PMID:23658809 PMID:28478070 RGD:12738215 RGD:12910733 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,028,499...72,056,438 		JBrowse link
G MGARP mitochondria localized glutamic acid rich protein involved_in ISO (MGI:3850758|PMID:19528298) UniProt PMID:19528298 MGI:3850758 NCBI chr 8:87,708,887...87,723,126
Ensembl chr 8:87,697,544...87,723,125 		JBrowse link
G MIEF1 mitochondrial elongation factor 1 ISO RGD PMID:25911325 RGD:12880381 NCBI chr 5:8,748,171...8,762,087 JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:19462902 RGD:4890975 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068 		JBrowse link
G MIR107 microRNA mir-107 ISO oxygen-glucose deprivation RGD PMID:26294080 RGD:11553310 NCBI chr14:101,420,743...101,420,829
Ensembl chr14:101,420,743...101,420,829 		JBrowse link
G MIR126 microRNA mir-126 involved_in ISO (PMID:28578351) BHF-UCL PMID:28578351
G MIR140 microRNA mir-140 involved_in ISO (PMID:27021683) BHF-UCL
RGD		 PMID:27021683 PMID:28922712 RGD:329347824 NCBI chr 6:17,077,530...17,077,599
Ensembl chr 6:17,077,507...17,077,620 		JBrowse link
G MIR143 microRNA mir-143 ISO RGD PMID:28887629 RGD:155882580 NCBI chr 2:150,578,738...150,578,817
Ensembl chr 2:150,578,738...150,578,817 		JBrowse link
G MIR17 microRNA mir-17 involved_in ISO (PMID:27640178) BHF-UCL PMID:27640178 NCBI chr11:60,734,656...60,734,732
Ensembl chr11:60,734,656...60,734,732 		JBrowse link
G MIR199A-1 microRNA mir-199a-1 acts_upstream_of_or_within ISO (PMID:24011070) MGI PMID:24011070 NCBI chr 9:114,533,783...114,533,858
Ensembl chr 9:114,533,777...114,533,880 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:31368162) BHF-UCL PMID:31368162 NCBI chr11:60,735,109...60,735,179
Ensembl chr11:60,735,099...60,735,196 		JBrowse link
G MIR214 microRNA mir-214 involved_in
acts_upstream_of_or_within		 ISO (PMID:27144530)
(PMID:24011070)		 BHF-UCL
MGI		 PMID:24011070 PMID:27144530 NCBI chr 9:114,527,992...114,528,101
Ensembl chr 9:114,527,990...114,528,101 		JBrowse link
G MIR222 microRNA mir-222 ISO RGD PMID:28854428 RGD:152025191 NCBI chr  X:40,571,808...40,571,887
Ensembl chr  X:40,571,808...40,571,887 		JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor ISO RGD PMID:15642952 RGD:10449018 NCBI chr 6:167,896,191...167,908,988
Ensembl chr 6:167,896,287...167,908,625 		JBrowse link
G MST1 macrophage stimulating 1 ISO RGD PMID:23647599 RGD:10448278 NCBI chr13:32,214,934...32,220,045
Ensembl chr13:32,214,937...32,219,902 		JBrowse link
G MSTN myostatin ISO RGD PMID:30765322 RGD:329849112 NCBI chr15:94,623,526...94,628,440
Ensembl chr15:94,620,270...94,628,545 		JBrowse link
G MT3 metallothionein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,261...18,636,131 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G MYOCD myocardin ISO RGD PMID:20621093 RGD:5132874 NCBI chr12:56,931,628...57,029,258
Ensembl chr12:56,931,317...57,029,258 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase ISO oxygen-glucose deprivation RGD PMID:28528966 RGD:13781879 NCBI chr 9:106,119,896...106,162,126
Ensembl chr 9:106,119,899...106,294,586 		JBrowse link
G NDNF neuron derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:103,047,783...103,094,800
Ensembl chr 8:102,996,281...103,088,230 		JBrowse link
G NDP norrin cystine knot growth factor NDP involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30988181) Ensembl
MGI		 PMID:30988181 GO_REF:0000107 NCBI chr  X:39,208,115...39,235,879
Ensembl chr  X:39,208,119...39,235,758 		JBrowse link
G NDRG1 N-myc downstream regulated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:8,014,445...8,069,335
Ensembl chr 4:8,014,446...8,069,335 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:23904790 GO_REF:0000107 RGD:10412703 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NGB neuroglobin involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:100,341,974...100,346,263
Ensembl chr 7:100,340,940...100,346,438 		JBrowse link
G NKX3-1 NK3 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:7,783,296...7,787,036
Ensembl chr14:7,783,323...7,787,033 		JBrowse link
G NOG noggin ISO RGD PMID:25740156 RGD:12801489 NCBI chr12:32,891,321...32,892,206
Ensembl chr12:32,891,321...32,892,206 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,443,453...53,451,707
Ensembl chr 6:53,443,385...53,452,017 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107
G NPEPPS aminopeptidase puromycin sensitive involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,804,839...23,892,055
Ensembl chr12:23,799,425...23,892,051 		JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:21444791 RGD:11535018 NCBI chr16:52,767,263...52,781,862
Ensembl chr16:52,765,298...52,781,771 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO RGD PMID:27833818 RGD:12910766 NCBI chr13:130,624,771...130,718,345
Ensembl chr13:130,624,796...130,719,083 		JBrowse link
G OPRD1 opioid receptor delta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:85,775,576...85,827,170
Ensembl chr 6:85,785,276...85,830,877 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,121,816...1,131,291
Ensembl chr12:1,121,824...1,131,289 		JBrowse link
G PALLD palladin, cytoskeletal associated protein ISO RGD PMID:16481593 RGD:2325785 NCBI chr14:20,678,456...21,020,125
Ensembl chr14:20,678,452...21,020,125 		JBrowse link
G PARK7 Parkinsonism associated deglycase ISO RGD PMID:29069575 RGD:151347449 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,516 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 ISO RGD PMID:24177414 RGD:10445837 NCBI chr17:57,930,507...57,936,523
Ensembl chr17:57,930,432...57,936,522 		JBrowse link
G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:23647599 RGD:10448278 NCBI chr 1:16,202,859...16,249,879
Ensembl chr 1:16,198,223...16,249,531 		JBrowse link
G PGK1 phosphoglycerate kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:62,187,472...62,210,321
Ensembl chr  X:62,187,434...62,210,705 		JBrowse link
G PHB2 prohibitin 2 ISO RGD PMID:25031298 RGD:12903263 NCBI chr 5:63,751,566...63,756,480
Ensembl chr 5:63,751,558...63,756,478 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:78,863,195...78,884,663
Ensembl chr 6:78,863,190...78,884,640 		JBrowse link
G PLAU plasminogen activator, urokinase ISO RGD PMID:19490965 RGD:7241802 NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14699081), (PMID:20810912) UniProt PMID:14699081 PMID:20810912 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24011070) Ensembl
MGI		 PMID:24011070 GO_REF:0000107 NCBI chr 7:31,222,533...31,295,221
Ensembl chr 7:31,222,585...31,295,211 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO PMID:29695452 BHF-UCL PMID:29695452 RGD:150521636 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22527940 RGD:7242177 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,946,992 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO oxygen-glucose deprivation RGD PMID:21525936 RGD:10054236 NCBI chr 6:54,172,038...54,175,461
Ensembl chr 6:54,172,050...54,175,463 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:17720864 RGD:2316813 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18070622) Ensembl
MGI		 PMID:18070622 GO_REF:0000107 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,866,306 		JBrowse link
G PRL prolactin involved_in IMP (PMID:24530842) AgBase PMID:24530842 NCBI chr 7:17,451,367...17,463,771
Ensembl chr 7:17,451,367...17,463,710 		JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:24875179) MGI PMID:24875179 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTGIS prostaglandin I2 synthase involved_in ISS
ISO
IEA		 UniProt
RGD
Ensembl		 PMID:19344900 GO_REF:0000024 GO_REF:0000107 RGD:401960096 NCBI chr17:51,153,151...51,200,515
Ensembl chr17:51,153,154...51,200,300 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G PTN pleiotrophin ISO RGD PMID:16226713 PMID:17925408 RGD:10044023 RGD:9834996 NCBI chr18:12,219,708...12,309,045
Ensembl chr18:12,219,787...12,309,044 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO RGD PMID:18278556 RGD:401965430 NCBI chr17:52,017,100...52,086,747
Ensembl chr17:52,017,130...52,086,736 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D ISO RGD PMID:35848503 RGD:401976433 NCBI chr 1:211,832,409...214,013,013
Ensembl chr 1:213,483,348...214,009,893 		JBrowse link
G RGCC regulator of cell cycle involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:25,481,845...25,496,548
Ensembl chr11:25,478,879...25,496,519 		JBrowse link
G RNF146 ring finger protein 146 ISO RGD PMID:26218637 RGD:13524866 NCBI chr 1:35,909,789...35,927,265
Ensembl chr 1:35,909,575...35,926,968 		JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO oxygen-glucose deprivation RGD PMID:23994690 RGD:243048442 NCBI chr13:175,348,223...176,479,482
Ensembl chr13:175,348,410...176,479,481 		JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,719,004...111,482,807
Ensembl chr 1:111,375,457...111,477,703 		JBrowse link
G RTN4 reticulon 4 involved_in ISO (MGI:6274961|PMID:27763637) UniProt PMID:27763637 MGI:6274961 NCBI chr 3:86,180,022...86,252,126
Ensembl chr 3:86,180,022...86,252,126 		JBrowse link
G S100B S100 calcium binding protein B ISO RGD PMID:19910580 RGD:2325647
G SCN2A sodium voltage-gated channel alpha subunit 2 involved_in ISO PMID:28029095 UniProt PMID:28029095 RGD:14390052 NCBI chr15:71,864,753...71,999,219
Ensembl chr15:71,864,784...71,999,211 		JBrowse link
G SDHD succinate dehydrogenase complex subunit D acts_upstream_of_or_within ISO (PMID:15572694) MGI PMID:15572694 NCBI chr 9:39,790,654...39,803,602
Ensembl chr 9:39,790,595...39,803,950 		JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:10590062 RGD:8547811 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,682,427...47,703,408
Ensembl chr 6:47,682,429...47,703,384 		JBrowse link
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr14:40,290,288...40,303,887
Ensembl chr14:40,290,288...40,303,879 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:21325818 RGD:5688411
G SLC29A1 solute carrier family 29 member 1 ISO RGD PMID:10646513 RGD:1598899 NCBI chr 7:39,217,974...39,234,683
Ensembl chr 7:39,218,051...39,234,685 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 ISO RGD PMID:20868366 RGD:7349316 NCBI chr12:52,628,746...52,634,965
Ensembl chr12:52,628,450...52,634,967 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO RGD PMID:17394575 RGD:1642726 NCBI chr 3:99,823,503...100,257,306
Ensembl chr 3:99,897,162...100,244,759 		JBrowse link
G SLC8A3 solute carrier family 8 member A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,643,609...93,797,483
Ensembl chr 7:93,643,618...93,796,917 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO RGD PMID:20868366 RGD:7349316 NCBI chr 6:84,373,921...84,426,447
Ensembl chr 6:84,372,649...84,426,997 		JBrowse link
G SLIT2 slit guidance ligand 2 ISO oxygen-glucose deprivation RGD PMID:26764532 RGD:11573340 NCBI chr 8:14,758,426...15,149,515
Ensembl chr 8:14,758,335...15,149,510 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:20380727 RGD:2324980 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860 		JBrowse link
G STC1 stanniocalcin 1 ISO RGD PMID:15485913 RGD:2324700 NCBI chr14:7,952,175...7,961,365
Ensembl chr14:7,950,434...7,961,566 		JBrowse link
G STC2 stanniocalcin 2 ISO RGD PMID:15485913 RGD:2324700 NCBI chr16:50,989,676...51,001,412
Ensembl chr16:50,989,433...51,004,481 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 ISO RGD PMID:17289031 RGD:9587773 NCBI chr15:105,820,237...105,850,099
Ensembl chr15:105,818,858...105,850,233 		JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21402781) MGI
Ensembl		 PMID:21402781 GO_REF:0000107 NCBI chr  X:42,797,309...42,811,457
Ensembl chr  X:42,797,828...42,811,461 		JBrowse link
G SUV39H2 SUV39H2 histone lysine methyltransferase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21402781) MGI
Ensembl		 PMID:21402781 GO_REF:0000107 NCBI chr10:46,874,606...46,900,058
Ensembl chr10:46,873,126...46,900,040 		JBrowse link
G TBL2 transducin beta like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,850,347...10,892,441
Ensembl chr 3:10,876,973...10,892,404 		JBrowse link
G TERT telomerase reverse transcriptase involved_in ISO
IEA		 RGD
Ensembl		 PMID:24376652 GO_REF:0000107 RGD:11038675 NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISO (PMID:31368162) BHF-UCL PMID:31368162 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:28854428 RGD:152025191 NCBI chr 5:12,185,816...12,242,599
Ensembl chr 5:12,185,818...12,242,581 		JBrowse link
G TP53 tumor protein p53 involved_in IEA
ISO		 Ensembl
RGD		 PMID:17289031 GO_REF:0000107 RGD:9587773 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO PMID:31900229 ARUK-UCL PMID:31900229 RGD:126781734 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 ISO RGD PMID:19889962 RGD:7247600 NCBI chr13:83,436,343...83,498,419
Ensembl chr13:83,436,395...83,498,478 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 ISO RGD PMID:19889962 RGD:7247600 NCBI chr 9:32,332,768...32,439,184
Ensembl chr 9:32,332,771...32,439,184 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:88,286,911...88,290,131
Ensembl chr 9:88,289,407...88,290,015 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:31,275,916...31,317,521
Ensembl chr10:31,275,868...31,317,516 		JBrowse link
G UCN2 urocortin 2 ISO RGD PMID:14519439 RGD:2306174 NCBI chr13:31,261,196...31,261,824
Ensembl chr13:31,261,196...31,261,534 		JBrowse link
G UCN3 urocortin 3 ISO RGD PMID:14519439 RGD:2306174 NCBI chr10:65,491,231...65,495,879 JBrowse link
G VASN vasorin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21658601) Ensembl
MGI		 PMID:21658601 GO_REF:0000107 NCBI chr 3:37,961,425...37,972,477
Ensembl chr 3:37,961,432...37,972,114 		JBrowse link
G VEGFA vascular endothelial growth factor A acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (PMID:10575000) MGI
Ensembl
UniProt		 PMID:10575000 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
G VLDLR very low density lipoprotein receptor ISO RGD PMID:19233325 RGD:2324641 NCBI chr 1:219,178,501...219,210,332
Ensembl chr 1:219,173,507...219,210,343 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:92,490,069...92,495,864
Ensembl chr 7:92,490,017...92,495,554 		JBrowse link
cellular response to oxygen-glucose deprivation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR2A activin A receptor type 2A ISO RGD PMID:27769861 RGD:329853763 NCBI chr15:4,177,333...4,259,056
Ensembl chr15:4,173,805...4,259,706 		JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:neuronal PC12 cells (rat) RGD PMID:27769861 RGD:329853763 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373 		JBrowse link
G INHBA inhibin subunit beta A ISO protein:increased expression:neuronal PC12 cells (rat) RGD PMID:27769861 RGD:329853763 NCBI chr12:53,115,379...53,117,128
NCBI chr18:52,889,684...52,909,260
Ensembl chr18:52,889,684...52,900,967 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO protein:increased expression:neuronal PC12 cells (rat) RGD PMID:27769861 RGD:329853763 NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO RGD PMID:27769861 RGD:329853763 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G OAZ1 ornithine decarboxylase antizyme 1 ISO RGD PMID:19531214 RGD:401851038 NCBI chr 2:76,293,142...76,296,626
Ensembl chr 2:76,293,150...76,296,620 		JBrowse link
hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GP91-PHOX NADPH oxidase heavy chain subunit ISO RGD PMID:21302291 RGD:11040609 NCBI chr  X:33,654,656...33,678,346
Ensembl chr  X:33,643,648...33,680,580 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8470821) Ensembl
MGI		 PMID:8470821 GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:78,608,394...78,650,958
Ensembl chr15:78,608,432...78,652,962 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:20,486,205...20,598,492
Ensembl chr  X:20,486,341...20,602,664 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in
acts_upstream_of		 IEA
ISO		 (PMID:25186293) Ensembl
MGI		 PMID:25186293 GO_REF:0000107 NCBI chr13:66,334,535...66,342,401
Ensembl chr13:66,334,591...66,342,654 		JBrowse link
intrinsic apoptotic signaling pathway in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF2 activating transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:80,984,969...81,076,573
Ensembl chr15:80,985,126...81,081,014 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) BHF-UCL PMID:20436456 NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,907 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20935145) Ensembl
MGI		 PMID:20935145 GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
negative regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAXX death domain associated protein ISO cell death RGD PMID:17289031 RGD:9587773 NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110 		JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:130,485,305...130,617,534
Ensembl chr 4:130,579,729...130,617,531 		JBrowse link
G DRD1 dopamine receptor D1 ISO cell death RGD PMID:27638511 RGD:13506952 NCBI chr16:49,189,555...49,193,722
Ensembl chr16:49,189,602...49,191,976 		JBrowse link
G DRD2 dopamine receptor D2 ISO cell death RGD PMID:27638511 RGD:13506952 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599 		JBrowse link
G EPHA4 EPH receptor A4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:31150684) ARUK-UCL
Ensembl		 PMID:31150684 GO_REF:0000107 NCBI chr15:123,350,867...123,501,872
Ensembl chr15:123,352,816...123,503,126 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO cell death RGD PMID:24048861 RGD:10412727 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO cell death RGD PMID:18539296 RGD:9590185 NCBI chr  X:57,521,091...57,558,467
Ensembl chr  X:57,521,098...57,558,515 		JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151 		JBrowse link
G HYOU1 hypoxia up-regulated 1 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:46,264,929...46,277,056
Ensembl chr 9:46,264,933...46,276,995 		JBrowse link
G KDM6A lysine demethylase 6A ISO RGD PMID:30887465 RGD:151665136 NCBI chr  X:39,953,764...40,154,197
Ensembl chr  X:39,953,814...40,154,029 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta involved_in ISO (MGI:6444553|PMID:30496354) BHF-UCL PMID:30496354 MGI:6444553 NCBI chr13:79,427,033...79,610,840
Ensembl chr13:79,425,835...79,610,840 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:78,863,195...78,884,663
Ensembl chr 6:78,863,190...78,884,640 		JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:15,674,028...15,692,944
Ensembl chr 5:15,674,057...15,692,936 		JBrowse link
negative regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COMMD1 copper metabolism domain containing 1 acts_upstream_of_or_within ISO (PMID:17371845) MGI PMID:17371845 NCBI chr 3:79,770,315...79,913,969
Ensembl chr 3:79,770,463...79,913,975 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25186293) Ensembl
MGI		 PMID:25186293 GO_REF:0000107 NCBI chr13:66,334,535...66,342,401
Ensembl chr13:66,334,591...66,342,654 		JBrowse link
positive regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha ISO oxygen-glucose deprivation-induced cell death RGD PMID:23516428 RGD:9589049 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087 		JBrowse link
G EP300 E1A binding protein p300 ISO reduced metabolism in hypoxia-treated PC12 cells
reduced metabolism in hypoxia mimic CoCl2-treated PC12 cells		 RGD PMID:18586071 PMID:19103185 RGD:2311713 RGD:2311718 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760 		JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:24705172 RGD:9831164 NCBI chr 9:128,429,232...128,659,662
Ensembl chr 9:128,429,092...128,661,639 		JBrowse link
G MIR145 microRNA mir-145 acts_upstream_of_or_within ISO (PMID:31150684) ARUK-UCL PMID:31150684 NCBI chr 2:150,580,126...150,580,211
Ensembl chr 2:150,580,126...150,580,211 		JBrowse link
positive regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RWDD3 RWD domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:22009797) InterPro
MGI
TreeGrafter
GO_Central
Ensembl		 PMID:22009797 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:122,187,949...122,203,146
Ensembl chr 4:122,187,952...122,203,115 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLK3 polo like kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:166,528,760...166,533,734
Ensembl chr 6:166,528,765...166,533,731 		JBrowse link
regulation of cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AJUBA ajuba LIM protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:76,063,009...76,072,884
Ensembl chr 7:76,063,058...76,076,585 		JBrowse link
G CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:16,812,409...16,819,130
Ensembl chr 3:16,812,404...16,819,124 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:18054269 RGD:9068899 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6271078|PMID:29353861) ARUK-UCL PMID:29353861 MGI:6271078 NCBI chr 3:125,353,063...125,493,368
Ensembl chr 3:125,352,920...125,493,362 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:19450559 RGD:7242910 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:31,726,668...31,738,135
Ensembl chr13:31,726,672...31,737,981 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in ISO (PMID:10205047) DisProt PMID:10205047 NCBI chr13:66,334,535...66,342,401
Ensembl chr13:66,334,591...66,342,654 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17813
    response to stimulus 10058
      response to abiotic stimulus 1552
        response to oxygen levels 591
          response to decreased oxygen levels 520
            cellular response to decreased oxygen levels 249
              cellular response to anoxia 4
              cellular response to hypoxia + 227
              cellular response to oxygen-glucose deprivation 6
              positive regulation of SREBP signaling pathway in response to decreased oxygen levels 0
paths to the root