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ONTOLOGY REPORT - ANNOTATIONS


Term:7-methylguanosine cap hypermethylation
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Accession:GO:0036261 term browser browse the term
Definition:Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.
Synonyms:exact_synonym: 2,2,7-trimethylguanosine cap formation;   TMG cap formation;   conversion of m(7)G to m(3)G;   m(7)G cap hypermethylation
 narrow_synonym: hypermethylation of snRNA cap;   hypermethylation of snoRNA cap;   snRNA capping;   snoRNA capping



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7-methylguanosine cap hypermethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgs1 trimethylguanosine synthase 1 involved_in ISO
IBA
(PMID:16687569)
GO_REF:0000033
RGD
GO_Central
PMID:16687569 GO_REF:0000033 NCBI chr 5:16,524,864...16,558,399
Ensembl chr 5:16,524,874...16,558,399
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Term paths to the root
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Term Annotations click to browse term
  biological_process 20292
    metabolic process 11721
      methylation 189
        macromolecule methylation 86
          RNA methylation 79
            7-methylguanosine cap hypermethylation 1
Path 2
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11721
      nitrogen compound metabolic process 9680
        cellular nitrogen compound metabolic process 6735
          nucleobase-containing compound metabolic process 5709
            nucleic acid metabolic process 5116
              RNA metabolic process 4520
                RNA processing 1025
                  RNA 5'-end processing 27
                    RNA capping 7
                      7-methylguanosine cap hypermethylation 1
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