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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:cleavage furrow formation
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Accession:GO:0036089 term browser browse the term
Definition:Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.
Comment:Consider also annotating to 'establishment of contractile ring localization involved in cell cycle cytokinesis ; GO:0032188'.
Synonyms:narrow_synonym: cleavage furrow positioning



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cleavage furrow formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in IMP
IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16103226)
Ensembl
UniProt
RGD
PMID:16103226 PMID:9450992 GO_REF:0000024 GO_REF:0000107, RGD:730040 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Rhoa ras homolog family member A involved_in ISO
ISS
(PMID:16103226)
GO_REF:0000024
RGD
UniProt
PMID:16103226 GO_REF:0000024 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Snx18 sorting nexin 18 involved_in ISO
IBA
(PMID:22718350)
PMID:21873635
RGD PMID:22718350 PMID:21873635 RGD:13792537 NCBI chr 2:45,232,325...45,258,345
Ensembl chr 2:45,232,325...45,258,345
JBrowse link
G Snx33 sorting nexin 33 involved_in ISO
IBA
(PMID:22718350)
PMID:21873635
RGD PMID:22718350 PMID:21873635 RGD:13792537 NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538
JBrowse link
G Snx9 sorting nexin 9 involved_in ISO
IBA
(PMID:22718350)
PMID:21873635
RGD PMID:22718350 PMID:21873635 RGD:13792537 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036
JBrowse link
G Spire1 spire-type actin nucleation factor 1 involved_in IBA
ISO
PMID:21873635
(MGI:5050782|PMID:21620703)
RGD PMID:21620703 PMID:21873635 MGI:5050782, RGD:13792537 NCBI chr18:61,041,914...61,171,670
Ensembl chr18:61,041,290...61,171,899
JBrowse link
G Spire2 spire-type actin nucleation factor 2 involved_in IBA
ISO
PMID:21873635
(MGI:5050782|PMID:21620703)
RGD PMID:21620703 PMID:21873635 MGI:5050782, RGD:13792537 NCBI chr19:51,373,368...51,411,920
Ensembl chr19:51,373,228...51,411,920
JBrowse link
mitotic cleavage furrow formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:16103226)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:16103226 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19527
    cellular process 18201
      cell cycle process 1281
        cytokinetic process 43
          cleavage furrow formation 7
            mitotic cleavage furrow formation 1
Path 2
Term Annotations click to browse term
  biological_process 19527
    cellular process 18201
      cellular component organization or biogenesis 6825
        cellular component organization 6564
          membrane organization 791
            membrane invagination 79
              plasma membrane invagination 71
                cleavage furrow formation 7
                  mitotic cleavage furrow formation 1
paths to the root