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Term:tetrahydrofolate interconversion
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Accession:GO:0035999 term browser browse the term
Definition:The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
Synonyms:xref: MetaCyc:PWY-2201;   UniPathway:UPA00193

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tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chrNW_004936549:6,838,773...6,899,961 JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chrNW_004936495:8,100,977...8,170,244 JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:21163947 RGD:7244288 NCBI chrNW_004936598:1,401,392...1,514,314 JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO (PMID:12673793)
(PMID:12673793), (PMID:25736335)
BHF-UCL PMID:10551815 PMID:12673793 PMID:25736335 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) BHF-UCL PMID:12764149 NCBI chrNW_004936471:37,910,856...37,964,655 JBrowse link
G Sardh sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chrNW_004936669:3,244,302...3,297,906 JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:24698160) BHF-UCL PMID:24698160 NCBI chrNW_004936741:1,849,239...1,877,724 JBrowse link
G Tyms thymidylate synthetase involved_in ISO (PMID:15093541) BHF-UCL PMID:15093541 NCBI chrNW_004936550:33,797...42,233 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12130
    metabolic process 7607
      small molecule metabolic process 1206
        one-carbon metabolic process 12
          tetrahydrofolate interconversion 8
Path 2
Term Annotations click to browse term
  biological_process 12130
    metabolic process 7607
      organic substance metabolic process 7333
        organonitrogen compound metabolic process 4365
          cellular modified amino acid metabolic process 130
            folic acid-containing compound metabolic process 18
              tetrahydrofolate metabolic process 15
                tetrahydrofolate interconversion 8
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