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ONTOLOGY REPORT - ANNOTATIONS


Term:tetrahydrofolate interconversion
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Accession:GO:0035999 term browser browse the term
Definition:The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
Synonyms:xref: MetaCyc:PWY-2201;   UniPathway:UPA00193


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tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 5:78,997,564...79,069,674
Ensembl chr 5:78,997,564...79,236,038
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase involved_in IEA UniProt GO_REF:0000041 NCBI chr21:46,135,981...46,156,482
Ensembl chr21:46,136,160...46,155,579
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISS
IBA
IDA
IEA
(PMID:21873635)
(PMID:1881876)
BHF-UCL
GO_Central
UniProt
PMID:1881876 PMID:21873635 GO_REF:0000024 GO_REF:0000041 NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 6:150,865,684...151,101,887
Ensembl chr 6:150,865,679...151,101,887
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:74,198,591...74,217,565
Ensembl chr 2:74,186,172...74,217,565
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IEA
IBA
ISO
(PMID:21873635) UniProt
GO_Central
RGD
PMID:21163947 PMID:21873635 GO_REF:0000041 RGD:7244288 NCBI chr 4:74,123,273...74,303,099
Ensembl chr 4:74,114,174...74,303,099
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IDA
IBA
IEA
IMP
IGI
(PMID:12673793)
(PMID:21873635)
(PMID:12673793), (PMID:25736335)
(PMID:10551815)
BHF-UCL
GO_Central
UniProt
PMID:10551815 PMID:12673793 PMID:21873635 PMID:25736335 GO_REF:0000041 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTHFS methenyltetrahydrofolate synthetase involved_in IMP
IBA
(PMID:12764149)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:12764149 PMID:21873635 NCBI chr15:79,843,547...79,897,285
Ensembl chr15:79,833,585...79,897,379
JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 9:133,663,074...133,739,958
Ensembl chr 9:133,663,560...133,739,955
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IBA
IEA
IDA
(PMID:21873635)
(PMID:24698160)
GO_Central
UniProt
BHF-UCL
PMID:21873635 PMID:24698160 GO_REF:0000041 NCBI chr17:18,327,873...18,363,560
Ensembl chr17:18,327,860...18,363,563
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr12:57,229,685...57,234,935
Ensembl chr12:57,229,573...57,234,935
JBrowse link
G TYMS thymidylate synthetase involved_in IDA (PMID:15093541) BHF-UCL PMID:15093541 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18666
    metabolic process 12186
      small molecule metabolic process 2037
        one-carbon metabolic process 42
          tetrahydrofolate interconversion 12
Path 2
Term Annotations click to browse term
  biological_process 18666
    metabolic process 12186
      organic substance metabolic process 11700
        organonitrogen compound metabolic process 7064
          cellular modified amino acid metabolic process 224
            folic acid-containing compound metabolic process 32
              tetrahydrofolate metabolic process 22
                tetrahydrofolate interconversion 12
paths to the root