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ONTOLOGY REPORT - ANNOTATIONS


Term:tetrahydrofolate interconversion
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Accession:GO:0035999 term browser browse the term
Definition:The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
Synonyms:xref: MetaCyc:PWY-2201;   UniPathway:UPA00193


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tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 3:27,789,089...27,857,348
Ensembl chr 3:27,790,324...27,856,601
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase involved_in IEA UniProt GO_REF:0000041 NCBI chr31:39,451,557...39,464,249
Ensembl chr31:39,275,159...39,464,715
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 1:41,316,247...41,495,226
Ensembl chr 1:41,309,419...41,495,216
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:48,882,838...48,896,816
Ensembl chr17:48,883,724...48,941,949
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:21163947 PMID:21873635 RGD:7244288 NCBI chr13:62,670,543...62,803,270
Ensembl chr13:62,670,462...62,803,519
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818
JBrowse link
G MTHFS methenyltetrahydrofolate synthetase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:57,480,935...57,514,836 JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 9:50,030,397...50,093,556
Ensembl chr 9:50,030,707...50,091,553
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr10:1,357,347...1,362,511
Ensembl chr10:1,356,706...1,362,305
JBrowse link
G TYMS thymidylate synthetase involved_in ISO (PMID:15093541) BHF-UCL PMID:15093541 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16215
    metabolic process 10493
      small molecule metabolic process 1615
        one-carbon metabolic process 38
          tetrahydrofolate interconversion 12
Path 2
Term Annotations click to browse term
  biological_process 16215
    metabolic process 10493
      organic substance metabolic process 10079
        organonitrogen compound metabolic process 6074
          cellular modified amino acid metabolic process 184
            folic acid-containing compound metabolic process 26
              tetrahydrofolate metabolic process 20
                tetrahydrofolate interconversion 12
paths to the root