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Term:tetrahydrofolate interconversion
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Accession:GO:0035999 term browser browse the term
Definition:The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
Synonyms:xref: MetaCyc:PWY-2201;   UniPathway:UPA00193

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tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chrNW_004955425:22,045,977...22,103,381
Ensembl chrNW_004955425:22,045,993...22,102,852
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chrNW_004955466:5,422,141...5,485,773
Ensembl chrNW_004955466:5,420,702...5,485,773
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:21163947 RGD:7244288 NCBI chrNW_004955474:450,676...558,659
Ensembl chrNW_004955474:450,680...558,716
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO (PMID:12673793)
(PMID:12673793), (PMID:25736335)
BHF-UCL PMID:10551815 PMID:12673793 PMID:25736335 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) BHF-UCL PMID:12764149 NCBI chrNW_004955533:720,255...756,893 JBrowse link
G Sardh sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chrNW_004955513:2,933,918...2,975,645
Ensembl chrNW_004955513:2,933,918...2,976,931
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:24698160) BHF-UCL PMID:24698160 NCBI chrNW_004955478:10,972,791...11,001,535
Ensembl chrNW_004955478:10,978,139...11,001,202
JBrowse link
G Tyms thymidylate synthetase involved_in ISO (PMID:15093541) BHF-UCL PMID:15093541 NCBI chrNW_004955402:9,295,862...9,304,952
Ensembl chrNW_004955402:9,296,321...9,306,631
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11940
    metabolic process 7525
      small molecule metabolic process 1191
        one-carbon metabolic process 12
          tetrahydrofolate interconversion 8
Path 2
Term Annotations click to browse term
  biological_process 11940
    metabolic process 7525
      organic substance metabolic process 7255
        organonitrogen compound metabolic process 4314
          cellular modified amino acid metabolic process 127
            folic acid-containing compound metabolic process 18
              tetrahydrofolate metabolic process 15
                tetrahydrofolate interconversion 8
paths to the root