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Term:tetrahydrofolate interconversion
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Accession:GO:0035999 term browser browse the term
Definition:The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
Synonyms:xref: MetaCyc:PWY-2201;   UniPathway:UPA00193

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tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 5:36,241,341...36,313,995
Ensembl chr 5:36,732,005...36,805,883
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:21163947 RGD:7244288 NCBI chr 4:49,889,607...50,034,860
Ensembl chr 4:55,722,237...55,867,117
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in ISO (PMID:10551815)
(PMID:12673793), (PMID:25736335)
BHF-UCL PMID:10551815 PMID:12673793 PMID:25736335 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 9:104,786,774...104,864,480
Ensembl chr 9:133,398,806...133,473,642
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:24698160) BHF-UCL PMID:24698160 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220
JBrowse link
G TYMS thymidylate synthetase involved_in ISO (PMID:15093541) BHF-UCL PMID:15093541 NCBI chr18:13,653,085...13,668,478
Ensembl chr18:17,295,182...17,310,320
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12616
    metabolic process 7893
      small molecule metabolic process 1275
        one-carbon metabolic process 11
          tetrahydrofolate interconversion 7
Path 2
Term Annotations click to browse term
  biological_process 12616
    metabolic process 7893
      organic substance metabolic process 7606
        organonitrogen compound metabolic process 4499
          cellular modified amino acid metabolic process 138
            folic acid-containing compound metabolic process 18
              tetrahydrofolate metabolic process 15
                tetrahydrofolate interconversion 7
paths to the root