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ONTOLOGY REPORT - ANNOTATIONS

Term:chondrocyte proliferation
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Accession:GO:0035988 term browser browse the term
Definition:The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.
Synonyms:exact_synonym: cartilage cell proliferation;   chondrocyte cell proliferation


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chondrocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 acts_upstream_of_or_within ISO MGI:2663631 (MGI:4413658|PMID:18597638) RGD PMID:18597638 MGI:4413658 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Col9a1 collagen type IX alpha 1 chain acts_upstream_of_or_within ISO MGI:88469 (MGI:3807836|PMID:18191556) RGD PMID:18191556 MGI:3807836 NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213 		JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3758741|MGI:5550566|MGI:88465 (MGI:3723532|PMID:17588960), (MGI:3807836|PMID:18191556), (MGI:5550565|PMID:22006726)		 Ensembl
RGD		 PMID:17588960 PMID:18191556 PMID:22006726 GO_REF:0000107 MGI:3723532 MGI:3807836 MGI:5550565 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO (MGI:2158837|PMID:11375938) RGD PMID:11375938 MGI:2158837 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:4431165|PMID:20080592) RGD PMID:20080592 MGI:4431165 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Golgb1 golgin B1 IMP RGD PMID:21851869 RGD:40902994 NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770 		JBrowse link
G Grn granulin precursor IMP RGD PMID:17307734 RGD:5509047 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS		 (PMID:21484705)
GO_REF:0000024		 RGD
UniProt		 PMID:21484705 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1934258 (MGI:4999722|PMID:16935278) RGD PMID:16935278 MGI:4999722 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Mmp14 matrix metallopeptidase 14 acts_upstream_of_or_within ISO MGI:1276107 (MGI:3771253|PMID:18022611) RGD PMID:18022611 MGI:3771253 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp16 matrix metallopeptidase 16 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:101900 (MGI:3771253|PMID:18022611)		 Ensembl
RGD		 PMID:18022611 GO_REF:0000107 MGI:3771253 NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388 		JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:6,072,908...6,075,158
Ensembl chr16:6,072,833...6,075,161 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in ISO
IEA		 MGI:3774275 (MGI:3770504|PMID:17728275)
GO_REF:0000107		 RGD
Ensembl		 PMID:17728275 GO_REF:0000107 MGI:3770504 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
G Slc26a2 solute carrier family 26 member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6708267|PMID:24302720)		 UniProt
RGD		 PMID:24302720 GO_REF:0000024 MGI:6708267 NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626 		JBrowse link
G Stc1 stanniocalcin 1 involved_in ISO (PMID:16377640) RGD PMID:16377640 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
negative regulation of chondrocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:9442116) RGD PMID:9442116 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21871891)		 UniProt
RGD		 PMID:21871891 GO_REF:0000024 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (MGI:5912858|PMID:25027178) RGD PMID:25027178 MGI:5912858 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:24577233) RGD PMID:24577233 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6377914|PMID:29503843)		 Ensembl
RGD		 PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
positive regulation of chondrocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3709418|PMID:17307734)		 Ensembl
RGD		 PMID:17307734 GO_REF:0000107 MGI:3709418 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (MGI:5588521|PMID:23900597) RGD PMID:23900597 MGI:5588521 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6277636|PMID:30659184)
GO_REF:0000107		 RGD
Ensembl		 PMID:30659184 GO_REF:0000107 MGI:6277636 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:15166119) RGD PMID:15166119 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (MGI:5703727|PMID:19410023) RGD PMID:19410023 MGI:5703727 NCBI chr16:6,072,908...6,075,158
Ensembl chr16:6,072,833...6,075,161 		JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:6363078 (MGI:6277636|PMID:30659184)
GO_REF:0000107		 RGD
Ensembl		 PMID:30659184 GO_REF:0000107 MGI:6277636 NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919 		JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 acts_upstream_of_or_within ISO MGI:5698367 (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr 1:163,831,876...163,899,925
Ensembl chr 1:163,832,015...163,899,393 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:25819580) RGD PMID:25819580 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (MGI:4822095|PMID:20515681) RGD PMID:20515681 MGI:4822095 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (PMID:29503843) RGD PMID:29503843 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    cellular process 17392
      cell population proliferation 2277
        chondrocyte proliferation 27
          negative regulation of chondrocyte proliferation 5
          positive regulation of chondrocyte proliferation 10
paths to the root