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ONTOLOGY REPORT - ANNOTATIONS

Term:aggrephagy
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Accession:GO:0035973 term browser browse the term
Definition:The selective degradation of protein aggregates by macroautophagy.
Synonyms:alt_id: GO:0035972


show annotations for term's descendants           Sort by:
aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG4A autophagy related 4A cysteine peptidase involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:108,088,829...108,154,671
Ensembl chr  X:108,091,668...108,154,671 		JBrowse link
G ATG4B autophagy related 4B cysteine peptidase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:241,637,693...241,673,857
Ensembl chr 2:241,637,213...241,673,857 		JBrowse link
G ATG4C autophagy related 4C cysteine peptidase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:62,784,132...62,865,516
Ensembl chr 1:62,784,132...62,865,516 		JBrowse link
G ATG4D autophagy related 4D cysteine peptidase involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:10,543,904...10,553,418
Ensembl chr19:10,543,895...10,553,418 		JBrowse link
G ATG5 autophagy related 5 involved_in IEA
IMP		 (PMID:22982048) Ensembl
ParkinsonsUK-UCL		 PMID:22982048 GO_REF:0000107 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G MAP1LC3C microtubule associated protein 1 light chain 3 gamma involved_in IMP (PMID:28404643) UniProt PMID:28404643 NCBI chr 1:241,995,490...242,001,393
Ensembl chr 1:241,995,490...241,999,098 		JBrowse link
G SQSTM1 sequestosome 1 involved_in IPI
IDA
IEA
IBA		 (PMID:28404643)
(PMID:17580304), (PMID:22017874), (PMID:29343546), (PMID:29507397), (PMID:31857589), (PMID:37306101), (PMID:37802024)		 UniProt
TreeGrafter
GO_Central
Ensembl		 PMID:17580304 PMID:22017874 PMID:28404643 PMID:29343546 PMID:29507397 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IDA (PMID:21143716) UniProt PMID:21143716 NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958 		JBrowse link
G WDFY3 WD repeat and FYVE domain containing 3 involved_in IMP
IBA
IEA		 (PMID:20168092), (PMID:20417604) GO_Central
TreeGrafter		 PMID:20168092 PMID:20417604 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:84,669,597...84,966,690
Ensembl chr 4:84,668,765...84,966,690 		JBrowse link
G WDR81 WD repeat domain 81 involved_in IMP
IBA
IEA		 (PMID:28404643) UniProt
GO_Central
TreeGrafter		 PMID:28404643 GO_REF:0000033 GO_REF:0000118 NCBI chr17:1,716,523...1,738,585
Ensembl chr17:1,716,523...1,738,599 		JBrowse link
negative regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC6 histone deacetylase 6 involved_in IDA (PMID:31857589) UniProt PMID:31857589 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G LYPLA1 lysophospholipase 1 involved_in IDA (PMID:37802024) UniProt PMID:37802024 NCBI chr 8:54,046,367...54,101,947
Ensembl chr 8:54,046,367...54,102,017 		JBrowse link
positive regulation of aggrephagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG3 BAG cochaperone 3 involved_in IMP (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in IDA (PMID:22017874) UniProt PMID:22017874 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835 		JBrowse link
G HSPB8 heat shock protein family B (small) member 8 involved_in IMP (PMID:18006506) ARUK-UCL PMID:18006506 NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855 		JBrowse link
G HTT huntingtin involved_in IMP (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,363...3,243,957 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IDA (PMID:31857589) UniProt PMID:31857589 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604 		JBrowse link
G ZDHHC19 zinc finger DHHC-type palmitoyltransferase 19 involved_in IDA (PMID:37802024) UniProt PMID:37802024 NCBI chr 3:196,197,452...196,211,400
Ensembl chr 3:196,197,452...196,211,437 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    cellular process 18460
      process utilizing autophagic mechanism 629
        autophagy 629
          macroautophagy 369
            aggrephagy 18
              negative regulation of aggrephagy 2
              positive regulation of aggrephagy 6
              regulation of aggrephagy + 8
Path 2
Term Annotations click to browse term
  biological_process 19770
    metabolic process 12509
      catabolic process 2943
        cellular catabolic process 1899
          autophagy 629
            macroautophagy 369
              aggrephagy 18
                negative regulation of aggrephagy 2
                positive regulation of aggrephagy 6
                regulation of aggrephagy + 8
paths to the root