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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to topologically incorrect protein
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Accession:GO:0035967 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
Synonyms:related_synonym: cellular response to misfolded or unfolded protein

show annotations for term's descendants           Sort by:
 
cellular response to topologically incorrect protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 ISO (PMID:16192271) RGD PMID:16192271 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671 		JBrowse link
cellular response to misfolded protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr12:22,665,128...22,676,079
Ensembl chr12:22,665,112...22,676,075 		JBrowse link
G Atxn3 ataxin 3 ISS
ISO		 GO_REF:0000024
(MGI:5318000|PMID:21855799)		 UniProt
RGD		 PMID:21855799 GO_REF:0000024 MGI:5318000 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461 		JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 ISO
IBA		 (PMID:21148293), (PMID:21150129)
PMID:21873635		 RGD PMID:21148293 PMID:21150129, PMID:21873635 RGD:13792537 NCBI chr20:29,445,510...29,463,739
Ensembl chr20:29,445,510...29,463,738 		JBrowse link
G Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:243,108,443...243,151,933
Ensembl chr 2:243,018,975...243,151,933 		JBrowse link
G Dnajc18 DnaJ heat shock protein family (Hsp40) member C18 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:28,466,892...28,501,013
Ensembl chr18:28,466,311...28,495,937 		JBrowse link
G Hdac6 histone deacetylase 6 ISO MGI:3776868 (MGI:3757892|PMID:17785525) RGD PMID:17785525 MGI:3757892 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671 		JBrowse link
G LOC103694506 ubiquitin-conjugating enzyme E2 W ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:119,160,964...119,178,031
Ensembl chr  X:119,160,959...119,162,518 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 IDA PMID:23444373 MGI PMID:23444373 RGD:8554667 NCBI chr11:88,122,271...88,124,513
Ensembl chr11:88,122,271...88,124,513 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 ISO
IBA		 (PMID:16831871)
PMID:21873635
(MGI:5318000|PMID:21855799)		 RGD PMID:16831871 PMID:21855799, PMID:21873635 MGI:5318000, RGD:13792537 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117 		JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W ISS
ISO		 GO_REF:0000024
(MGI:5318000|PMID:21855799)		 UniProt
RGD		 PMID:21855799 GO_REF:0000024 MGI:5318000 NCBI chr 5:29,798,845...29,812,777 JBrowse link
cellular response to unfolded protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07011951.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:177,651,241...177,653,288 JBrowse link
G AABR07033324.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr11:17,336,444...17,340,373 JBrowse link
G AABR07048992.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 5:99,031,013...99,033,107 JBrowse link
G Bag3 BAG cochaperone 3 ISO (PMID:18006506) RGD PMID:18006506 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191 		JBrowse link
G Daxx death-domain associated protein ISO
IEA
ISS		 (PMID:15016915)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15016915 GO_REF:0000024 GO_REF:0000107 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926 		JBrowse link
G Derl1 derlin 1 ISO (MGI:4361100|PMID:19509052) RGD PMID:19509052 MGI:4361100 NCBI chr 7:97,737,176...97,759,852
Ensembl chr 7:97,737,178...97,759,852 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO (PMID:19328063), (PMID:20625543) RGD PMID:19328063 PMID:20625543 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Hsc70-ps1 heat shock cognate protein 70, pseudogene 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:177,651,231...177,653,349 JBrowse link
G Hsf1 heat shock transcription factor 1 ISO (PMID:15016915) RGD PMID:15016915 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478 		JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:14,146,515...14,160,697
Ensembl chr11:14,144,130...14,160,892 		JBrowse link
G Hspa14 heat shock protein family A (Hsp70) member 14 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:78,735,630...78,756,412
Ensembl chr17:78,735,598...78,756,399 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO
IBA		 (PMID:20625543)
PMID:21873635		 RGD PMID:20625543, PMID:21873635 RGD:13792537 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO
IBA		 (PMID:20625543)
PMID:21873635		 RGD PMID:20625543, PMID:21873635 RGD:13792537 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 ISO
IBA		 (PMID:18006506)
PMID:21873635		 RGD PMID:18006506, PMID:21873635 RGD:13792537 NCBI chr12:45,905,371...45,920,014
Ensembl chr12:45,905,371...45,920,013 		JBrowse link
G LOC100363133 heat shock cognate 71 kDa protein-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:99,030,998...99,033,110 JBrowse link
G LOC108348108 heat shock 70 kDa protein 1A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:2,699,707...2,701,856
Ensembl chr20:4,877,324...4,879,779
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G LOC680121 similar to heat shock protein 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:13,499,168...13,501,271
Ensembl chr11:13,499,164...13,501,263 		JBrowse link
G Optn optineurin IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:27534431)		 Ensembl
UniProt
RGD		 PMID:27534431 GO_REF:0000024 GO_REF:0000107 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389 		JBrowse link
G Pmp22 peripheral myelin protein 22 ISO GO:0034620 (MGI:5517729|PMID:23847051) RGD PMID:23847051 MGI:5517729 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 ISO
IBA
ISS		 (PMID:22795130)
PMID:21873635
(MGI:5437551|PMID:22795130)
GO_REF:0000024		 RGD
UniProt		 PMID:22795130, PMID:21873635 GO_REF:0000024 MGI:5437551, RGD:13792537 NCBI chr 9:88,110,731...88,229,462
Ensembl chr 9:88,110,731...88,229,479 		JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 ISO
ISS		 (PMID:27740623)
(MGI:5909200|PMID:27740623)
GO_REF:0000024		 RGD
UniProt		 PMID:27740623 GO_REF:0000024 MGI:5909200 NCBI chr 4:180,913,703...180,951,564
Ensembl chr 4:180,913,706...180,951,564 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 IEA
ISO		 GO_REF:0000107
(MGI:3840374|PMID:19328063)
(PMID:19328063)		 Ensembl
RGD		 PMID:19328063 GO_REF:0000107 MGI:3840374 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989 		JBrowse link
G Umod uromodulin IEA
ISO		 GO_REF:0000107
(MGI:5916257|PMID:28437467)		 Ensembl
RGD		 PMID:28437467 GO_REF:0000107 MGI:5916257 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376 		JBrowse link
cytoplasm protein quality control by the ubiquitin-proteasome system term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf126 ring finger protein 126 ISO (PMID:24981174) RGD PMID:24981174 NCBI chr 7:12,820,796...12,828,325
Ensembl chr 7:12,820,840...12,828,334 		JBrowse link
endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amfr autocrine motility factor receptor ISO
IBA		 (PMID:17157811)
PMID:21873635		 RGD PMID:17157811, PMID:21873635 RGD:13792537 NCBI chr19:11,473,538...11,509,500
Ensembl chr19:11,473,541...11,508,102 		JBrowse link
G Atf3 activating transcription factor 3 ISO (MGI:3722921|PMID:14729979) RGD PMID:14729979 MGI:3722921 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632 		JBrowse link
G Atf4 activating transcription factor 4 ISS
ISO		 GO_REF:0000024
(MGI:5496937|PMID:23624402)		 UniProt
RGD		 PMID:23624402 GO_REF:0000024 MGI:5496937 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Atf6 activating transcription factor 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443 		JBrowse link
G Atf6b activating transcription factor 6 beta IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 ISS
ISO		 GO_REF:0000024
(MGI:5607242|PMID:17612490)		 UniProt
RGD		 PMID:17612490 GO_REF:0000024 MGI:5607242 NCBI chr12:12,403,385...12,409,103
Ensembl chr12:12,403,385...12,407,561 		JBrowse link
G Calr calreticulin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666 		JBrowse link
G Calr3 calreticulin 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:19,097,391...19,124,062
Ensembl chr16:19,097,391...19,124,062 		JBrowse link
G Calr4 calreticulin 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:128,865,339...128,900,135
Ensembl chr 5:128,865,389...128,899,792 		JBrowse link
G Canx calnexin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861 		JBrowse link
G Casp12 caspase 12 IEA
ISO		 GO_REF:0000107
(MGI:1858648|PMID:10882126)		 Ensembl
RGD		 PMID:10882126 GO_REF:0000107 MGI:1858648 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160 		JBrowse link
G Ccnd1 cyclin D1 ISO (MGI:3620306|PMID:16176978) RGD PMID:16176978 MGI:3620306 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:23152784)		 Ensembl
UniProt
RGD		 PMID:23152784 GO_REF:0000024 GO_REF:0000107 NCBI chr10:84,780,644...84,789,800
Ensembl chr10:84,780,608...84,789,832 		JBrowse link
G Clgn calmegin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:24,545,257...24,578,527
Ensembl chr19:24,545,318...24,576,798 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 ISS
ISO		 GO_REF:0000024
(MGI:4438316|PMID:19767743)		 UniProt
RGD		 PMID:19767743 GO_REF:0000024 MGI:4438316 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283 		JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:64,869,285...64,981,519
Ensembl chr 4:64,869,026...64,981,384 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282 		JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:189,596,657...189,602,243
Ensembl chr 2:189,595,415...189,602,143 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEA
ISO
ISS		 GO_REF:0000107
MGI:2654034|MGI:5441015 (MGI:3525819|PMID:15601821), (MGI:5496937|PMID:23624402), (MGI:6270315|PMID:30188326)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15601821 PMID:23624402 PMID:30188326 GO_REF:0000024 GO_REF:0000107 MGI:3525819 MGI:5496937 MGI:6270315 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Derl1 derlin 1 ISO
IBA		 (PMID:15215856)
PMID:21873635		 RGD PMID:15215856, PMID:21873635 RGD:13792537 NCBI chr 7:97,737,176...97,759,852
Ensembl chr 7:97,737,178...97,759,852 		JBrowse link
G Derl2 derlin 2 ISO
IBA		 (PMID:16449189)
PMID:21873635		 RGD PMID:16449189, PMID:21873635 RGD:13792537 NCBI chr10:57,641,682...57,653,554
Ensembl chr10:57,644,207...57,653,359 		JBrowse link
G Derl3 derlin 3 ISO
IBA		 (PMID:16449189)
PMID:21873635		 RGD PMID:16449189, PMID:21873635 RGD:13792537 NCBI chr20:13,692,102...13,707,645
Ensembl chr20:13,704,314...13,706,205 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 ISO (MGI:3511630|PMID:15542627) RGD PMID:15542627 MGI:3511630 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISS
ISO		 GO_REF:0000024
MGI:2177666 (MGI:1333015|PMID:9930704), (MGI:1858648|PMID:10882126), (MGI:2136067|PMID:11430819), (MGI:2677605|PMID:14517290), (MGI:3511630|PMID:15542627), (MGI:3583403|PMID:15911877), (MGI:3620306|PMID:16176978)
(PMID:10677345), (PMID:11907036), (PMID:22169477)		 UniProt
RGD		 PMID:9930704 PMID:10677345 PMID:10882126 PMID:11430819 PMID:11907036 PMID:14517290 PMID:15542627 PMID:15911877 PMID:16176978 PMID:22169477 GO_REF:0000024 MGI:1333015 MGI:1858648 MGI:2136067 MGI:2677605 MGI:3511630 MGI:3583403 MGI:3620306 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 ISO MGI:2387965 (MGI:3620306|PMID:16176978) RGD PMID:16176978 MGI:3620306 NCBI chr 3:110,159,624...110,245,382
Ensembl chr 3:110,159,708...110,249,217 		JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 ISO
IEA		 (PMID:27566589)
GO_REF:0000107		 RGD
Ensembl		 PMID:27566589 GO_REF:0000107 NCBI chr 1:247,784,830...247,821,771
Ensembl chr 1:247,787,582...247,821,728 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO (MGI:1858648|PMID:10882126), (MGI:2136067|PMID:11430819), (MGI:3525819|PMID:15601821) RGD PMID:10882126 PMID:11430819 PMID:15601821 MGI:1858648 MGI:2136067 MGI:3525819 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha ISO (MGI:3525819|PMID:15601821) RGD PMID:15601821 MGI:3525819 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381 		JBrowse link
G Fgf21 fibroblast growth factor 21 IEP RGD PMID:23123503 RGD:10401883 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 IMP
IBA
ISO		 PMID:21873635
(MGI:1913176|PMID:10922362)		 RGD PMID:10922362, PMID:15102845, PMID:21873635 MGI:1913176, RGD:1304324, RGD:13792537 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254 		JBrowse link
G Herpud2 HERPUD family member 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:26,266,571...26,311,528
Ensembl chr 8:26,266,760...26,311,350 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO
IBA		 (MGI:4437543|PMID:19816510)
PMID:21873635		 RGD PMID:19816510, PMID:21873635 MGI:4437543, RGD:13792537 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Ifng interferon gamma ISO (MGI:3583403|PMID:15911877) RGD PMID:15911877 MGI:3583403 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G LOC103694875 derlin-3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO (MGI:2677605|PMID:14517290) RGD PMID:14517290 MGI:2677605 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Parp16 poly (ADP-ribose) polymerase family, member 16 ISO
IBA		 (PMID:23103912)
PMID:21873635		 RGD PMID:23103912, PMID:21873635 RGD:13792537 NCBI chr 8:70,712,393...70,731,212
Ensembl chr 8:70,708,873...70,729,985 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IEP
ISO		 MGI:2652765 (MGI:3525819|PMID:15601821) RGD PMID:15601821, PMID:22154936, PMID:18266951 MGI:3525819, RGD:9999171, RGD:9999413 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 ISO
ISS		 (PMID:22169477)
GO_REF:0000024		 RGD
UniProt		 PMID:22169477 GO_REF:0000024 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848 		JBrowse link
G Rnf121 ring finger protein 121 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:167,095,916...167,165,257
Ensembl chr 1:167,095,962...167,165,265 		JBrowse link
G Selenos selenoprotein S ISO
IBA		 (PMID:15215856)
PMID:21873635		 RGD PMID:15215856, PMID:21873635 RGD:13792537 NCBI chr 1:126,979,579...126,989,344
Ensembl chr 1:126,979,575...126,989,344 		JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 ISO
IBA		 MGI:3652355 (MGI:3619104|PMID:16415102)
PMID:21873635		 RGD PMID:16415102, PMID:21873635 MGI:3619104, RGD:13792537 NCBI chr 2:148,718,279...148,722,263
Ensembl chr 2:148,718,280...148,722,263 		JBrowse link
G Serp2 stress-associated endoplasmic reticulum protein family member 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:58,687,784...58,712,023
Ensembl chr15:58,687,786...58,711,872 		JBrowse link
G Stc2 stanniocalcin 2 ISO (MGI:3511371|PMID:15485913) RGD PMID:15485913 MGI:3511371 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 ISO (MGI:5582182|PMID:12150907) RGD PMID:12150907 MGI:5582182 NCBI chr10:15,197,754...15,200,035
Ensembl chr10:15,197,803...15,200,117 		JBrowse link
G Tbl2 transducin (beta)-like 2 ISO (PMID:25393282) RGD PMID:25393282 NCBI chr12:24,565,843...24,578,855
Ensembl chr12:24,565,849...24,578,786 		JBrowse link
G Tmtc4 transmembrane O-mannosyltransferase targeting cadherins 4 ISO MGI:5008116 (MGI:6270315|PMID:30188326) RGD PMID:30188326 MGI:6270315 NCBI chr15:109,338,762...109,394,905
Ensembl chr15:109,339,564...109,394,927 		JBrowse link
G Vapb VAMP associated protein B and C ISO
ISS		 (PMID:16891305)
GO_REF:0000024		 RGD
UniProt		 PMID:16891305 GO_REF:0000024 NCBI chr 3:171,832,558...171,871,042
Ensembl chr 3:171,832,500...171,868,647 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein ISO
IBA		 (MGI:3629256|PMID:16571599), (MGI:4999711|PMID:19911006)
PMID:21873635		 RGD PMID:16571599 PMID:19911006, PMID:21873635 MGI:3629256 MGI:4999711, RGD:13792537 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966 		JBrowse link
G Xbp1 X-box binding protein 1 IDA
ISO		 (MGI:5573106|PMID:24753614), (MGI:5607242|PMID:17612490) RGD PMID:17612490 PMID:24753614, PMID:15171721 MGI:5573106 MGI:5607242, RGD:1304536 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145 		JBrowse link
G Yod1 YOD1 deubiquitinase ISO
IBA
ISS		 (PMID:19818707)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:19818707, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:47,441,296...47,443,013
Ensembl chr13:47,440,803...47,443,188 		JBrowse link
ER-associated misfolded protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor ISO
ISS		 (PMID:21857022)
GO_REF:0000024		 RGD
UniProt		 PMID:21857022 GO_REF:0000024 NCBI chr 4:113,887,030...113,890,103
Ensembl chr 4:113,887,115...113,890,101 		JBrowse link
G Bag6 BAG cochaperone 6 ISS
ISO		 GO_REF:0000024
(PMID:23129660), (PMID:24981174)		 UniProt
RGD		 PMID:23129660 PMID:24981174 GO_REF:0000024 NCBI chr20:5,124,512...5,138,084
Ensembl chr20:5,125,349...5,138,084 		JBrowse link
G Derl1 derlin 1 ISO (PMID:24089527) RGD PMID:24089527 NCBI chr 7:97,737,176...97,759,852
Ensembl chr 7:97,737,178...97,759,852 		JBrowse link
G Ngly1 N-glycanase 1 IMP RGD PMID:32259258 RGD:39457703 NCBI chr15:10,405,453...10,455,973
Ensembl chr15:10,405,164...10,455,956 		JBrowse link
G Pomt2 protein-O-mannosyltransferase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:111,137,329...111,176,991
Ensembl chr 6:111,135,349...111,176,918 		JBrowse link
G Rnf185 ring finger protein 185 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:83,648,400...83,685,273
Ensembl chr14:83,648,402...83,685,273 		JBrowse link
G Rnf5 ring finger protein 5 ISO
IBA		 (PMID:19269966)
PMID:21873635		 RGD PMID:19269966, PMID:21873635 RGD:13792537 NCBI chr20:4,366,244...4,368,690
Ensembl chr20:4,366,246...4,368,693 		JBrowse link
G Sdf2 stromal cell derived factor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:65,507,364...65,517,839
Ensembl chr10:65,507,364...65,517,838 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 IMP PMID:23444373 MGI PMID:23444373 RGD:8554667 NCBI chr11:88,122,271...88,124,513
Ensembl chr11:88,122,271...88,124,513 		JBrowse link
G Tor1a torsin family 1, member A ISS
ISO		 GO_REF:0000024
(MGI:3712415|PMID:17200151)		 UniProt
RGD		 PMID:17200151 GO_REF:0000024 MGI:3712415 NCBI chr 3:9,800,322...9,807,318
Ensembl chr 3:9,800,322...9,807,328 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 ISO
IBA		 (PMID:24089527)
PMID:21873635		 RGD PMID:24089527, PMID:21873635 RGD:13792537 NCBI chr11:86,304,836...86,328,478
Ensembl chr11:86,304,815...86,328,469 		JBrowse link
G Uggt1 UDP-glucose glycoprotein glucosyltransferase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:42,692,156...42,805,680
Ensembl chr 9:42,692,105...42,805,673 		JBrowse link
G Vcp valosin-containing protein ISO
IBA		 (PMID:24089527)
PMID:21873635		 RGD PMID:24089527, PMID:21873635 RGD:13792537 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953 		JBrowse link
IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO
IBA		 (PMID:11779465), (PMID:19328063), (PMID:28128204), (PMID:29198525), (PMID:9637683)
PMID:21873635
(MGI:5571560|PMID:24508390), (MGI:6114871|PMID:25164867)		 RGD PMID:9637683 PMID:11779465 PMID:19328063 PMID:24508390 PMID:25164867 PMID:28128204 PMID:29198525, PMID:21873635 MGI:5571560 MGI:6114871, RGD:13792537 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:192,126,023...192,142,865
Ensembl chr 1:192,126,023...192,142,854 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO (MGI:5571560|PMID:24508390) RGD PMID:24508390 MGI:5571560 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Parp16 poly (ADP-ribose) polymerase family, member 16 IEA
ISO		 GO_REF:0000107
(PMID:23103912)		 Ensembl
RGD		 PMID:23103912 GO_REF:0000107 NCBI chr 8:70,712,393...70,731,212
Ensembl chr 8:70,708,873...70,729,985 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 ISO (MGI:5616322|PMID:15465829) RGD PMID:15465829 MGI:5616322 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848 		JBrowse link
G Vapb VAMP associated protein B and C ISS
ISO		 GO_REF:0000024
(PMID:20940299)		 UniProt
RGD		 PMID:20940299 GO_REF:0000024 NCBI chr 3:171,832,558...171,871,042
Ensembl chr 3:171,832,500...171,868,647 		JBrowse link
mitochondrial unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07014739.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr14:29,232,295...29,232,537 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6b activating transcription factor 6 beta ISO (PMID:9837962) RGD PMID:9837962 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein ISO
IGI		 (PMID:20160352) RGD PMID:20160352, PMID:20160352 RGD:10047363 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966 		JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor ISO (PMID:18391022) RGD PMID:18391022 NCBI chr10:16,693,846...16,753,162
Ensembl chr10:16,694,792...16,752,205 		JBrowse link
G Xbp1 X-box binding protein 1 ISO (PMID:25239945) RGD PMID:25239945 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145 		JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator ISO (PMID:21068390) RGD PMID:21068390 NCBI chr10:1,464,658...1,471,152
NCBI chr10:1,464,783...1,497,653
Ensembl chr10:1,464,765...1,497,653 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 ISO (PMID:28128204), (PMID:32160526)
(MGI:5912977|PMID:28128204)		 RGD PMID:28128204 PMID:32160526 MGI:5912977 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 ISO (MGI:5571560|PMID:24508390) RGD PMID:24508390 MGI:5571560 NCBI chr 6:42,568,269...42,585,654
Ensembl chr 6:42,568,220...42,585,652 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 ISO
ISS		 (PMID:32160526)
GO_REF:0000024		 RGD
UniProt		 PMID:32160526 GO_REF:0000024 NCBI chr 5:39,616,479...39,650,894
Ensembl chr 5:39,615,956...39,650,895 		JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 ISO (MGI:5774886|PMID:27030769) RGD PMID:27030769 MGI:5774886 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341 		JBrowse link
G Nck1 NCK adaptor protein 1 ISO (PMID:14676213)
UniProtKB:O55033 (MGI:5613478|PMID:14676213)		 RGD PMID:14676213 MGI:5613478 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779 		JBrowse link
G Nck2 NCK adaptor protein 2 ISO UniProtKB:Q99M51 (MGI:5613478|PMID:14676213) RGD PMID:14676213 MGI:5613478 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 ISO (PMID:21216966)
(MGI:5619464|PMID:21216966)		 RGD PMID:21216966 MGI:5619464 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848 		JBrowse link
nuclear protein quality control by the ubiquitin-proteasome system term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cul3 cullin 3 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:27561354)		 Ensembl
UniProt
RGD		 PMID:27561354 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329 		JBrowse link
G Klhl15 kelch-like family member 15 ISO
ISS		 (PMID:27561354)
GO_REF:0000024		 RGD
UniProt		 PMID:27561354 GO_REF:0000024 NCBI chr  X:63,342,277...63,390,915
Ensembl chr  X:63,343,546...63,389,989 		JBrowse link
PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 ISS
ISO		 GO_REF:0000024
(MGI:3722921|PMID:14729979), (MGI:3798818|PMID:12667446)		 UniProt
RGD		 PMID:12667446 PMID:14729979 GO_REF:0000024 MGI:3722921 MGI:3798818 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:3722921|PMID:14729979), (MGI:6467680|PMID:17707796) RGD PMID:14729979 PMID:17707796 MGI:3722921 MGI:6467680 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO (MGI:2677605|PMID:14517290) RGD PMID:14517290 MGI:2677605 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 ISO MGI:4456438 (MGI:5914333|PMID:28797121) RGD PMID:28797121 MGI:5914333 NCBI chr12:37,471,259...37,480,344
Ensembl chr12:37,471,260...37,480,297 		JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6 activating transcription factor 6 ISO (PMID:9837962) RGD PMID:9837962 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443 		JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 ISO (PMID:16645094) RGD PMID:16645094 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:16645094)		 Ensembl
UniProt
RGD		 PMID:16645094 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO (PMID:16645094), (PMID:28128204) RGD PMID:16645094 PMID:28128204 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:20348923)		 Ensembl
UniProt
RGD		 PMID:20348923 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867 		JBrowse link
G Xbp1 X-box binding protein 1 ISO
IEA		 (PMID:16645094)
GO_REF:0000107		 RGD
Ensembl		 PMID:16645094 GO_REF:0000107 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145 		JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO (PMID:23220234) RGD PMID:23220234 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714 		JBrowse link
G Tmem33 transmembrane protein 33 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:26268696)		 Ensembl
UniProt
RGD		 PMID:26268696 GO_REF:0000024 GO_REF:0000107 NCBI chr14:42,537,352...42,559,580
Ensembl chr14:42,535,701...42,560,174 		JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO (PMID:23220234) RGD PMID:23220234 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK ISS
ISO		 GO_REF:0000024
(MGI:5648772|PMID:26015568)		 UniProt
RGD		 PMID:26015568 GO_REF:0000024 MGI:5648772 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027 		JBrowse link
G Tmem33 transmembrane protein 33 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:26268696)		 Ensembl
UniProt
RGD		 PMID:26268696 GO_REF:0000024 GO_REF:0000107 NCBI chr14:42,537,352...42,559,580
Ensembl chr14:42,535,701...42,560,174 		JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein NOT ISO (PMID:21803450) RGD PMID:21803450 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 ISO (PMID:16940180), (PMID:18391022) RGD PMID:16940180 PMID:18391022 NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188 		JBrowse link
G Ep300 E1A binding protein p300 ISO (MGI:5607229|PMID:20955178) RGD PMID:20955178 MGI:5607229 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296 		JBrowse link
G Xbp1 X-box binding protein 1 ISO
IBA
ISS		 (PMID:25239945)
PMID:21873635
(MGI:5605954|PMID:14559994), (MGI:5607229|PMID:20955178), (MGI:5607243|PMID:16332684)
GO_REF:0000024		 RGD
UniProt		 PMID:14559994 PMID:16332684 PMID:20955178 PMID:25239945, PMID:21873635 GO_REF:0000024 MGI:5605954 MGI:5607229 MGI:5607243, RGD:13792537 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145 		JBrowse link
regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pigbos1 PIGB opposite strand 1 ISO
ISS		 (PMID:31653868)
GO_REF:0000024		 RGD
UniProt		 PMID:31653868 GO_REF:0000024 NCBI chr 8:79,715,337...79,719,706 JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops5 COP9 signalosome subunit 5 ISO (PMID:15234121) RGD PMID:15234121 NCBI chr 5:8,876,090...8,894,345
Ensembl chr 5:8,876,044...8,894,339 		JBrowse link
G Ficd FIC domain protein adenylyltransferase ISS
ISO		 GO_REF:0000024
(PMID:25601083)		 UniProt
RGD		 PMID:25601083 GO_REF:0000024 NCBI chr12:48,658,283...48,663,175
Ensembl chr12:48,658,283...48,663,143 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20044
    response to stimulus 10558
      response to stress 4042
        response to topologically incorrect protein 144
          cellular response to topologically incorrect protein 124
            cellular response to misfolded protein + 25
            cellular response to unfolded protein + 101
Path 2
Term Annotations click to browse term
  biological_process 20044
    response to stimulus 10558
      response to chemical 6329
        response to organic substance 3873
          response to topologically incorrect protein 144
            cellular response to topologically incorrect protein 124
              cellular response to misfolded protein + 25
              cellular response to unfolded protein + 101
paths to the root