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ONTOLOGY REPORT - ANNOTATIONS

Term:response to topologically incorrect protein
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Accession:GO:0035966 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
Synonyms:related_synonym: response to misfolded or unfolded protein


show annotations for term's descendants           Sort by:
ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Manf mesencephalic astrocyte-derived neurotrophic factor involved_in ISO (PMID:27984733) RGD PMID:27984733 NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:107,548,352...107,551,438 		JBrowse link
cellular response to misfolded protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn3 ataxin 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21855799)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21855799 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:126,837,107...126,872,919
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24089527)		 Ensembl
RGD		 PMID:24089527 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Derl1 derlin 1 involved_in ISO (PMID:24089527) RGD PMID:24089527 NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 involved_in ISO
IEA
IBA		 (PMID:21148293), (PMID:21150129)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21148293 PMID:21150129 GO_REF:0000033 GO_REF:0000107 NCBI chr20:27,828,216...27,846,428
Ensembl chr20:27,828,235...27,846,427 		JBrowse link
G Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490 		JBrowse link
G Dnajc18 DnaJ heat shock protein family (Hsp40) member C18 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:27,269,350...27,303,453
Ensembl chr18:27,269,355...27,298,344 		JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within ISO
IEA		 MGI:3776868 (PMID:17785525)
GO_REF:0000107		 RGD
Ensembl		 PMID:17785525 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 acts_upstream_of_or_within IDA PMID:23444373 MGI PMID:23444373 RGD:8554667 NCBI chr11:97,376,878...97,379,120
Ensembl chr11:83,872,659...83,874,902 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO
IEA		 (PMID:16831871)
GO_REF:0000107
(PMID:21855799)		 RGD
Ensembl		 PMID:16831871 PMID:21855799 GO_REF:0000107 NCBI chr10:15,355,278...15,357,559
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W involved_in ISS
ISO		 GO_REF:0000024
(PMID:21855799)		 UniProt
RGD		 PMID:21855799 GO_REF:0000024 NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24089527)		 Ensembl
RGD		 PMID:24089527 GO_REF:0000107 NCBI chr11:95,665,971...95,689,423
Ensembl chr11:82,161,619...82,185,087 		JBrowse link
G Vcp valosin-containing protein involved_in ISO
IEA		 (PMID:24089527)
GO_REF:0000107		 RGD
Ensembl		 PMID:24089527 GO_REF:0000107 NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
cellular response to topologically incorrect protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in ISO
IEA		 (PMID:16192271)
GO_REF:0000107		 RGD
Ensembl		 PMID:16192271 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
cellular response to unfolded protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 involved_in ISO
IEA		 (PMID:18006506)
GO_REF:0000107		 RGD
Ensembl		 PMID:18006506 GO_REF:0000107 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Daxx death-domain associated protein involved_in ISO
IEA
ISS		 (PMID:15016915)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15016915 GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Derl1 derlin 1 acts_upstream_of_or_within ISO (PMID:19509052) RGD PMID:19509052 NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO
IEA		 (PMID:19328063), (PMID:20625543), (PMID:21317875)
GO_REF:0000107		 RGD
Ensembl		 PMID:19328063 PMID:20625543 PMID:21317875 GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO
IEA		 (PMID:15016915)
GO_REF:0000107		 RGD
Ensembl		 PMID:15016915 GO_REF:0000107 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 involved_in ISO
IEA
IBA		 (PMID:18006506)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033		 RGD
Ensembl
InterPro
GO_Central		 PMID:18006506 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:45,835,899...45,866,449
Ensembl chr12:40,176,532...40,191,185 		JBrowse link
G Optn optineurin involved_in ISO
IEA
ISS		 (PMID:27534431)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:27534431 GO_REF:0000024 GO_REF:0000107 NCBI chr17:78,118,847...78,169,543
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO GO:0034620 (PMID:23847051) RGD PMID:23847051 NCBI chr10:48,294,932...48,324,941
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:22795130)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:22795130 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:91,076,786...91,196,719
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27740623)		 UniProt
Ensembl
RGD		 PMID:27740623 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:179,518,127...179,550,154
Ensembl chr 4:179,518,130...179,550,154 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA		 (PMID:19328063)
GO_REF:0000033		 RGD
GO_Central		 PMID:19328063 GO_REF:0000033 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO
IEA		 (PMID:28437467)
GO_REF:0000107		 RGD
Ensembl		 PMID:28437467 GO_REF:0000107 NCBI chr 1:183,247,676...183,261,665
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
cytoplasm protein quality control by the ubiquitin-proteasome system term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf126 ring finger protein 126 involved_in ISO
IEA		 (PMID:24981174)
GO_REF:0000107		 RGD
Ensembl		 PMID:24981174 GO_REF:0000107 NCBI chr 7:10,590,013...10,597,585
Ensembl chr 7:9,938,229...9,946,738 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in ISO
IEA
ISS		 (PMID:29033132)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29033132 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in ISO
IEA
ISS		 (PMID:29033132)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29033132 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:71,000,197...71,109,841
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amfr autocrine motility factor receptor involved_in ISO
IEA
IBA		 (PMID:17157811)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:17157811 GO_REF:0000033 GO_REF:0000107 NCBI chr19:11,002,451...11,038,182
Ensembl chr19:10,996,099...11,032,247 		JBrowse link
G Asb11 ankyrin repeat and SOCS box containing 11 involved_in ISO
IEA		 (PMID:31387940)
GO_REF:0000107		 RGD
Ensembl		 PMID:31387940 GO_REF:0000107 NCBI chr  X:33,646,389...33,669,790
Ensembl chr  X:29,992,416...30,037,807 		JBrowse link
G Atf3 activating transcription factor 3 involved_in ISO
IEA		 (PMID:14729979)
GO_REF:0000107		 RGD
Ensembl		 PMID:14729979 GO_REF:0000107 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23624402)		 UniProt
Ensembl
RGD		 PMID:23624402 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:85,460,312...85,639,959
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atf6b activating transcription factor 6 beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,095,534...4,103,534
Ensembl chr20:4,090,921...4,098,894 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17612490)		 UniProt
RGD		 PMID:17612490 GO_REF:0000024 NCBI chr12:15,534,123...15,538,299
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Casp12 caspase 12 acts_upstream_of_or_within ISO
IEA		 (PMID:10882126)
GO_REF:0000107		 RGD
Ensembl		 PMID:10882126 GO_REF:0000107 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Ccnd1 cyclin D1 acts_upstream_of_or_within ISO
IEA		 (PMID:16176978)
GO_REF:0000107		 RGD
Ensembl		 PMID:16176978 GO_REF:0000107 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO
IEA
ISS		 (PMID:23152784)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23152784 GO_REF:0000024 GO_REF:0000107 NCBI chr10:82,390,845...82,402,814
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO
IEA		 (PMID:16940180)
GO_REF:0000107
(PMID:18391022)		 RGD
Ensembl		 PMID:16940180 PMID:18391022 GO_REF:0000107 NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:57,817,832...57,824,390 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19767743)		 UniProt
RGD		 PMID:19767743 GO_REF:0000024 NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:77,952,540...77,993,456 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23624402)
MGI:2654034|MGI:5441015 (PMID:15601821), (PMID:30188326)		 UniProt
Ensembl
RGD		 PMID:15601821 PMID:23624402 PMID:30188326 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Derl1 derlin 1 involved_in ISO (PMID:15215856) RGD PMID:15215856 NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Derl2 derlin 2 involved_in ISO
IEA
IBA		 (PMID:16449189)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16449189 GO_REF:0000033 GO_REF:0000107 NCBI chr10:56,226,340...56,238,038
Ensembl chr10:55,727,643...55,739,518 		JBrowse link
G Derl3 derlin 3 involved_in ISO
IEA
IBA		 (PMID:16449189)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16449189 GO_REF:0000033 GO_REF:0000107 NCBI chr20:12,753,926...12,766,478
Ensembl chr20:12,763,543...12,767,027 		JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 acts_upstream_of_or_within ISO (PMID:15542627) RGD PMID:15542627 NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
MGI:2177666 (PMID:10882126), (PMID:11430819), (PMID:14517290), (PMID:15542627), (PMID:15911877), (PMID:16176978), (PMID:9930704)
(PMID:10677345), (PMID:11907036), (PMID:22169477)		 UniProt
Ensembl
RGD		 PMID:9930704 PMID:10677345 PMID:10882126 PMID:11430819 PMID:11907036 More... GO_REF:0000024 GO_REF:0000107 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 acts_upstream_of_or_within ISO MGI:2387965 (PMID:16176978) RGD PMID:16176978 NCBI chr 3:125,810,207...125,895,574
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G ENSRNOG00000066502 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 9:2,759,881...2,760,635 JBrowse link
G ENSRNOG00000069918 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 9:2,654,884...2,655,638 JBrowse link
G ENSRNOG00000070059 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 9:2,698,519...2,699,273 JBrowse link
G ENSRNOG00000070668 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 9:3,071,123...3,071,876 JBrowse link
G Erlec1 endoplasmic reticulum lectin 1 involved_in IEA GO_REF:0000104
GO_REF:0000002		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:108,856,661...108,894,511
Ensembl chr14:104,655,673...104,693,480 		JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 acts_upstream_of_or_within ISO (PMID:27566589) RGD PMID:27566589 NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:227,387,920...227,436,909 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10882126), (PMID:11430819), (PMID:15601821)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:10882126 PMID:11430819 PMID:15601821 GO_REF:0000002 GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha acts_upstream_of_or_within ISO
IEA		 (PMID:15601821)
GO_REF:0000107		 RGD
Ensembl		 PMID:15601821 GO_REF:0000107 NCBI chr15:20,974,771...21,010,170
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Fgf21 fibroblast growth factor 21 IEP RGD PMID:23123503 RGD:10401883 NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:10922362)
GO_REF:0000033		 RGD
GO_Central		 PMID:10922362 GO_REF:0000033 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Herpud2 HERPUD family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:31,849,216...31,894,219
Ensembl chr 8:23,573,379...23,617,874 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:19816510)		 GO_Central
Ensembl
RGD		 PMID:19816510 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Ifnb1 interferon beta 1 IEP RGD PMID:18412159 RGD:401854236 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:15911877) RGD PMID:15911877 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 acts_upstream_of_or_within ISO
IEA		 (PMID:14517290)
GO_REF:0000107		 RGD
Ensembl		 PMID:14517290 GO_REF:0000107 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Os9 OS9, endoplasmic reticulum lectin involved_in IEA GO_REF:0000002
GO_REF:0000104		 InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 7:64,802,517...64,829,185
Ensembl chr 7:62,915,515...62,943,745 		JBrowse link
G Parp16 poly (ADP-ribose) polymerase family, member 16 involved_in ISO
IEA
IBA		 (PMID:23103912)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23103912 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:65,731,152...65,749,438
Ensembl chr 8:65,727,706...65,749,433 		JBrowse link
G Parp6 poly (ADP-ribose) polymerase family, member 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:60,016,594...60,049,108
Ensembl chr 8:60,016,877...60,049,108 		JBrowse link
G Parp8 poly (ADP-ribose) polymerase family, member 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:48,679,405...48,848,700
Ensembl chr 2:48,679,436...48,849,253 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A acts_upstream_of_or_within IEP
ISO		 MGI:2652765 (PMID:15601821) RGD PMID:15601821 PMID:22154936 PMID:18266951 RGD:9999171, RGD:9999413 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IEA
ISS		 (PMID:22169477)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22169477 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Qrich1 glutamine-rich 1 involved_in ISO
IEA		 (PMID:33384352)
GO_REF:0000107		 RGD
Ensembl		 PMID:33384352 GO_REF:0000107 NCBI chr 8:118,095,435...118,135,001
Ensembl chr 8:109,217,376...109,261,359 		JBrowse link
G Rnf7 ring finger protein 7 involved_in ISO
IEA		 (PMID:31387940)
GO_REF:0000107		 RGD
Ensembl		 PMID:31387940 GO_REF:0000107 NCBI chr 8:97,038,845...97,048,080
Ensembl chr 8:97,038,840...97,047,824 		JBrowse link
G Selenos selenoprotein S involved_in ISO
IBA
IEA		 (PMID:15215856)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:15215856 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:119,659,751...119,669,833 		JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:3652355 (PMID:16415102)		 GO_Central
Ensembl
RGD		 PMID:16415102 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116 		JBrowse link
G Serp2 stress-associated endoplasmic reticulum protein family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:58,289,148...58,313,224
Ensembl chr15:51,879,877...51,904,785 		JBrowse link
G Stc2 stanniocalcin 2 acts_upstream_of_or_within ISO
IEA		 (PMID:15485913)
GO_REF:0000107		 RGD
Ensembl		 PMID:15485913 GO_REF:0000107 NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO
IEA		 (PMID:12150907)
GO_REF:0000107		 RGD
Ensembl		 PMID:12150907 GO_REF:0000107 NCBI chr10:15,355,278...15,357,559
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Tbl2 transducin (beta)-like 2 involved_in ISO
IEA
IBA		 (PMID:25393282)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:25393282 GO_REF:0000033 GO_REF:0000107 NCBI chr12:27,154,150...27,168,446
Ensembl chr12:21,520,682...21,531,896 		JBrowse link
G Tmbim4 transmembrane BAX inhibitor motif containing 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:55,718,690...55,733,277
Ensembl chr 7:55,718,699...55,742,773 		JBrowse link
G Tmtc4 transmembrane O-mannosyltransferase targeting cadherins 4 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:5008116 (PMID:30188326)		 GO_Central
Ensembl
RGD		 PMID:30188326 GO_REF:0000033 GO_REF:0000107 NCBI chr15:106,406,795...106,463,226
Ensembl chr15:100,000,152...100,056,543 		JBrowse link
G Vapb VAMP associated protein B and C involved_in ISO
IEA
ISS		 (PMID:16891305)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16891305 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:162,535,974...162,578,747
Ensembl chr 3:162,535,905...162,573,763 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO
IEA
IBA		 (PMID:16571599), (PMID:19911006)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16571599 PMID:19911006 GO_REF:0000033 GO_REF:0000107 NCBI chr14:78,035,205...78,059,718
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in IDA
IEA
ISO
ISS		 GO_REF:0000107
(PMID:17612490), (PMID:24753614)
(PMID:16332684)
(PMID:14559994)
(PMID:31387940)
(PMID:25239945)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:14559994 PMID:16332684 PMID:17612490 PMID:24753614 PMID:25239945 More... GO_REF:0000024 GO_REF:0000107, RGD:1304536 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Yod1 YOD1 deubiquitinase involved_in ISO
IBA
ISS		 (PMID:19818707)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:19818707 GO_REF:0000024 GO_REF:0000033 NCBI chr13:44,727,319...44,733,933
Ensembl chr13:42,174,820...42,177,205 		JBrowse link
IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:65,232,697...65,272,719 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO
IEA
IBA		 (PMID:11779465), (PMID:19328063), (PMID:28128204), (PMID:29198525), (PMID:9637683)
GO_REF:0000107
(PMID:24508390), (PMID:25164867)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9637683 PMID:11779465 PMID:19328063 PMID:24508390 PMID:25164867 More... GO_REF:0000033 GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISO (PMID:24508390) RGD PMID:24508390 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Parp16 poly (ADP-ribose) polymerase family, member 16 involved_in ISO
IEA		 (PMID:23103912)
GO_REF:0000107		 RGD
Ensembl		 PMID:23103912 GO_REF:0000107 NCBI chr 8:65,731,152...65,749,438
Ensembl chr 8:65,727,706...65,749,433 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in IMP PMID:24508390 WB PMID:24508390 RGD:596936193 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IEA		 (PMID:15465829)
GO_REF:0000107		 RGD
Ensembl		 PMID:15465829 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Vapb VAMP associated protein B and C involved_in ISO
IEA
ISS		 (PMID:20940299)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20940299 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:162,535,974...162,578,747
Ensembl chr 3:162,535,905...162,573,763 		JBrowse link
mitochondrial unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP binding cassette subfamily B member 10 involved_in ISO
IEA		 (PMID:28315685)
GO_REF:0000107		 RGD
Ensembl		 PMID:28315685 GO_REF:0000107 NCBI chr19:51,952,655...51,982,910
Ensembl chr19:51,952,681...51,982,753 		JBrowse link
G ENSRNOG00000065699 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr14:100,606,613...100,607,588 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hspd1l1 heat shock protein family D (Hsp60) member 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:1,587,931...1,590,330
Ensembl chr18:1,588,008...1,590,314 		JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6b activating transcription factor 6 beta involved_in ISO
IEA		 (PMID:9837962)
GO_REF:0000107		 RGD
Ensembl		 PMID:9837962 GO_REF:0000107 NCBI chr20:4,095,534...4,103,534
Ensembl chr20:4,090,921...4,098,894 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in IGI
IEA
ISO		 PMID:20160352
GO_REF:0000107
(PMID:20160352)		 Ensembl
RGD		 PMID:20160352 PMID:20160352 GO_REF:0000107, RGD:10047363 NCBI chr14:78,035,205...78,059,718
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor involved_in ISO (PMID:18391022) RGD PMID:18391022 NCBI chr10:16,903,607...16,967,450
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Mir199a2 microRNA 199a-2 acts_upstream_of ISO (PMID:24299514) RGD PMID:24299514 NCBI chr13:77,116,225...77,116,334
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:25239945) RGD PMID:25239945 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfar bifunctional apoptosis regulator involved_in ISO
IEA		 (PMID:21068390)
GO_REF:0000107		 RGD
Ensembl		 PMID:21068390 GO_REF:0000107 NCBI chr10:2,059,189...2,092,207
Ensembl chr10:1,552,072...1,585,038 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO
IEA
IBA		 (PMID:28128204), (PMID:32160526)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:28128204 PMID:32160526 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISO (PMID:24508390) RGD PMID:24508390 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:19328063) RGD PMID:19328063 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
IEA
ISS		 (PMID:32160526)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:32160526 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:43,759,271...43,791,682
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (PMID:27030769) RGD PMID:27030769 NCBI chr 7:10,342,092...10,362,094
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21954288)		 Ensembl
RGD		 PMID:21954288 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21954288)		 Ensembl
RGD		 PMID:21954288 GO_REF:0000107 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 involved_in ISO (PMID:21954288) RGD PMID:21954288 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Atad3a ATPase family, AAA domain containing 3A involved_in ISO
IEA
ISS		 (PMID:39116259)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:39116259 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:171,632,545...171,652,725
Ensembl chr 5:166,350,304...166,370,482 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO
IEA		 (PMID:30842412)
GO_REF:0000107		 RGD
Ensembl		 PMID:30842412 GO_REF:0000107 NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISO
IEA		 (PMID:11907036)
GO_REF:0000107		 RGD
Ensembl		 PMID:11907036 GO_REF:0000107 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IEA
IBA		 (PMID:14676213)
GO_REF:0000107
GO_REF:0000033
UniProtKB:O55033 (PMID:14676213)		 RGD
Ensembl
GO_Central		 PMID:14676213 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:109,897,723...109,958,247
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IEA
IBA		 UniProtKB:Q99M51 (PMID:14676213)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:14676213 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:53,206,006...53,332,417
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IEA
IBA		 (PMID:21216966)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21216966 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
nuclear protein quality control by the ubiquitin-proteasome system term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akirin2 akirin 2 acts_upstream_of_positive_effect ISS
ISO		 GO_REF:0000024
(PMID:34711951)		 UniProt
RGD		 PMID:34711951 GO_REF:0000024 NCBI chr 5:53,897,792...53,918,873
Ensembl chr 5:49,108,220...49,122,568 		JBrowse link
G Cul3 cullin 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27561354)		 UniProt
Ensembl
RGD		 PMID:27561354 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Klhl15 kelch-like family member 15 involved_in ISO
IEA
IBA
ISS		 (PMID:27561354)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:27561354 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:62,987,762...63,043,980
Ensembl chr  X:58,995,461...59,046,069 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in ISO
IEA
ISS		 (PMID:37478846), (PMID:37478862)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:37478846 PMID:37478862 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:71,000,197...71,109,841
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31023583)
(PMID:12667446), (PMID:14729979)		 UniProt
Ensembl
RGD		 PMID:12667446 PMID:14729979 PMID:31023583 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO
IEA		 (PMID:10026192), (PMID:25925385), (PMID:31023583), (PMID:39116259)
GO_REF:0000107
(PMID:10882126), (PMID:14729979), (PMID:16418533), (PMID:17707796), (PMID:21954288), (PMID:29386355)		 RGD
Ensembl		 PMID:10026192 PMID:10882126 PMID:14729979 PMID:16418533 PMID:17707796 More... GO_REF:0000107 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31023583), (PMID:33384352)		 UniProt
Ensembl
RGD		 PMID:31023583 PMID:33384352 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO
IEA		 (PMID:14517290)
GO_REF:0000107		 RGD
Ensembl		 PMID:14517290 GO_REF:0000107 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Qrich1 glutamine-rich 1 involved_in ISO
IEA		 (PMID:33384352)
GO_REF:0000107		 RGD
Ensembl		 PMID:33384352 GO_REF:0000107 NCBI chr 8:118,095,435...118,135,001
Ensembl chr 8:109,217,376...109,261,359 		JBrowse link
G Rpap2 RNA polymerase II associated protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:30118681)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:30118681 GO_REF:0000024 GO_REF:0000107 NCBI chr14:2,109,044...2,187,343
Ensembl chr14:2,109,053...2,187,350 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO
IEA		 MGI:4456438 (PMID:28797121)
GO_REF:0000107		 RGD
Ensembl		 PMID:28797121 GO_REF:0000107 NCBI chr12:37,713,522...37,722,606
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6 activating transcription factor 6 involved_in ISO
IEA		 (PMID:9837962)
GO_REF:0000107		 RGD
Ensembl		 PMID:9837962 GO_REF:0000107 NCBI chr13:85,460,312...85,639,959
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO
IEA		 (PMID:28128204)
GO_REF:0000107		 RGD
Ensembl		 PMID:28128204 GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO
ISS		 (PMID:20348923)
GO_REF:0000024		 RGD
UniProt		 PMID:20348923 GO_REF:0000024 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO
IEA		 (PMID:23220234)
GO_REF:0000107		 RGD
Ensembl		 PMID:23220234 GO_REF:0000107 NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Tmem33 transmembrane protein 33 involved_in ISO
IEA
ISS		 (PMID:26268696)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26268696 GO_REF:0000024 GO_REF:0000107 NCBI chr14:41,242,358...41,264,586
Ensembl chr14:40,885,712...40,910,715 		JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO
IEA		 (PMID:23220234)
GO_REF:0000107		 RGD
Ensembl		 PMID:23220234 GO_REF:0000107 NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26015568)		 UniProt
Ensembl
RGD		 PMID:26015568 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21216966)		 Ensembl
RGD		 PMID:21216966 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Tmem33 transmembrane protein 33 involved_in ISO
IEA
ISS		 (PMID:26268696)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26268696 GO_REF:0000024 GO_REF:0000107 NCBI chr14:41,242,358...41,264,586
Ensembl chr14:40,885,712...40,910,715 		JBrowse link
regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pigbos1 PIGB opposite strand 1 involved_in ISO
IEA
ISS		 (PMID:31653868)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:31653868 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:82,656,376...82,660,745
Ensembl chr 8:73,775,732...73,780,102 		JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops5 COP9 signalosome subunit 5 involved_in ISO
IEA		 (PMID:15234121)
GO_REF:0000107		 RGD
Ensembl		 PMID:15234121 GO_REF:0000107 NCBI chr 5:13,975,198...13,993,391
Ensembl chr 5:9,192,100...9,210,731 		JBrowse link
G Ficd FIC domain protein adenylyltransferase involved_in ISO
ISS		 (PMID:25601083)
GO_REF:0000024		 RGD
UniProt		 PMID:25601083 GO_REF:0000024 NCBI chr12:48,549,737...48,554,626
Ensembl chr12:42,889,194...42,894,070 		JBrowse link
response to misfolded protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:19996109)		 Ensembl
UniProt
RGD		 PMID:19996109 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA		 (PMID:18725990)
GO_REF:0000107		 RGD
Ensembl		 PMID:18725990 GO_REF:0000107 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO
IEA		 (PMID:14675537)
GO_REF:0000107		 RGD
Ensembl		 PMID:14675537 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
response to unfolded protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf6 activating transcription factor 6 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:85,460,312...85,639,959
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Comp cartilage oligomeric matrix protein acts_upstream_of_or_within ISO
IEA		 MGI:3758741 (PMID:17588960)
GO_REF:0000107		 RGD
Ensembl		 PMID:17588960 GO_REF:0000107 NCBI chr16:19,081,172...19,089,548
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:57,817,832...57,824,390 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:77,952,540...77,993,456 		JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:66,874,623...66,990,962
Ensembl chr 4:65,907,655...66,023,763 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048 		JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:175,690,340...175,695,846
Ensembl chr 2:175,690,335...175,695,932 		JBrowse link
G Crebrf CREB3 regulatory factor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:16,903,607...16,967,450
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000043
(PMID:18940792)		 UniProt
Ensembl
RGD		 PMID:18940792 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Derl1 derlin 1 acts_upstream_of_or_within ISO (PMID:15215855) RGD PMID:15215855 NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 involved_in ISO
IEA		 (PMID:10570961)
GO_REF:0000107		 RGD
Ensembl		 PMID:10570961 GO_REF:0000107 NCBI chr 5:61,972,637...61,981,887
Ensembl chr 5:57,176,845...57,185,490 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:102,432,667...102,475,643
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:143,350,989...143,385,693
Ensembl chr 4:141,797,701...141,829,717 		JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:164,661,741...164,687,559
Ensembl chr 3:144,201,605...144,227,485 		JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Elp6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within ISO (PMID:27715390) RGD PMID:27715390 NCBI chr 8:119,158,380...119,173,483
Ensembl chr 8:110,279,979...110,295,067 		JBrowse link
G Epg5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_or_within ISO
IEA		 MGI:5505596 (PMID:27715390), (PMID:31628468)
GO_REF:0000107		 RGD
Ensembl		 PMID:27715390 PMID:31628468 GO_REF:0000107 NCBI chr18:73,679,106...73,776,694
Ensembl chr18:71,404,010...71,501,502 		JBrowse link
G Erp44 endoplasmic reticulum protein 44 involved_in ISO
IEA		 (PMID:11847130)
GO_REF:0000107		 RGD
Ensembl		 PMID:11847130 GO_REF:0000107 NCBI chr 5:67,313,245...67,406,207
Ensembl chr 5:62,516,551...62,610,761 		JBrowse link
G Faf2 Fas associated factor family member 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,952,329...9,994,596
Ensembl chr17:9,947,220...9,989,485 		JBrowse link
G Fbxo6 F-box protein 6 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:158,576,729...158,582,520
Ensembl chr 5:158,576,759...158,582,525 		JBrowse link
G Ficd FIC domain protein adenylyltransferase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr12:48,549,737...48,554,626
Ensembl chr12:42,889,194...42,894,070 		JBrowse link
G Gorasp2 golgi reassembly stacking protein 2 acts_upstream_of_or_within ISO
IEA		 (PMID:30880003)
GO_REF:0000107		 RGD
Ensembl		 PMID:30880003 GO_REF:0000107 NCBI chr 3:55,474,448...55,503,570
Ensembl chr 3:55,474,757...55,503,576 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IEA		 (PMID:10708769), (PMID:10922362)
GO_REF:0000107
GO_REF:0000043		 RGD
Ensembl
UniProt		 PMID:10708769 PMID:10922362 GO_REF:0000043 GO_REF:0000107 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Herpud2 HERPUD family member 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:31,849,216...31,894,219
Ensembl chr 8:23,573,379...23,617,874 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 TAS RGD PMID:14987991 RGD:1304538 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in IMP
ISS
ISO		 GO_REF:0000024
(PMID:10859165)		 UniProt
RGD		 PMID:10859165 PMID:12397389 GO_REF:0000024, RGD:1300068 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in IMP
ISS
ISO		 GO_REF:0000024
(PMID:10859165)		 UniProt
RGD		 PMID:10859165 PMID:8271311 GO_REF:0000024, RGD:1298961 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like involved_in IDA PMID:12423363 UniProt PMID:12423363 RGD:8554521 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:11050098) RGD PMID:11050098 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Jkamp JNK1/MAPK8-associated membrane protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:96,383,976...96,397,917
Ensembl chr 6:90,648,160...90,662,501 		JBrowse link
G Jkampl JNK1/MAPK8 associated membrane protein like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:105,520,442...105,521,542
Ensembl chr 4:105,520,442...105,521,542 		JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:107,548,352...107,551,438 		JBrowse link
G Mfn2 mitofusin 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Parp16 poly (ADP-ribose) polymerase family, member 16 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:65,731,152...65,749,438
Ensembl chr 8:65,727,706...65,749,433 		JBrowse link
G Pigbos1 PIGB opposite strand 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:82,656,376...82,660,745
Ensembl chr 8:73,775,732...73,780,102 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IEP RGD PMID:12472897 RGD:628414 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116 		JBrowse link
G Serp2 stress-associated endoplasmic reticulum protein family member 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:58,289,148...58,313,224
Ensembl chr15:51,879,877...51,904,785 		JBrowse link
G Stt3b STT3 oligosaccharyltransferase complex catalytic subunit B involved_in ISO (PMID:19167329), (PMID:22607976) RGD PMID:19167329 PMID:22607976 NCBI chr 8:114,928,678...114,994,027
Ensembl chr 8:114,917,824...114,994,028 		JBrowse link
G Thbs4 thrombospondin 4 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:25,718,219...25,760,345
Ensembl chr 2:23,983,158...24,026,313 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Tram1 translocation associated membrane protein 1 involved_in ISO
IEA
ISS		 (PMID:20430023)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20430023 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:10,425,710...10,450,669
Ensembl chr 5:5,642,546...5,686,971 		JBrowse link
G Ubxn4 UBX domain protein 4 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:39,740,064...39,772,493
Ensembl chr13:39,740,107...39,772,491 		JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO
IEA		 (PMID:29145399)
GO_REF:0000107		 RGD
Ensembl		 PMID:29145399 GO_REF:0000107 NCBI chr 1:183,247,676...183,261,665
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
G Vapb VAMP associated protein B and C involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:162,535,974...162,578,747
Ensembl chr 3:162,535,905...162,573,763 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Yod1 YOD1 deubiquitinase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:44,727,319...44,733,933
Ensembl chr13:42,174,820...42,177,205 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to stress 4344
        response to topologically incorrect protein 143
          cellular response to topologically incorrect protein + 115
          response to misfolded protein + 20
          response to unfolded protein + 125
paths to the root