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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiolipin acyl-chain remodeling
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Accession:GO:0035965 term browser browse the term
Definition:Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.
Synonyms:exact_synonym: cardiolipin acyl-chain remodelling
 broad_synonym: cardiolipin maturation
 related_synonym: diphosphatidylglycerol remodeling
 xref: Reactome:R-HSA-1482798 "Acyl chain remodeling of CL"
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe


show annotations for term's descendants           Sort by:
cardiolipin acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:23152787), (PMID:31604922)		 UniProt
RGD		 PMID:23152787 PMID:31604922 GO_REF:0000024 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO
ISS
IDA
IBA		 (PMID:23533611)
GO_REF:0000024
PMID:24648512
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:23533611 PMID:24648512 GO_REF:0000024 GO_REF:0000033, RGD:25671395 NCBI chr 7:112,731,803...112,771,978
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in IBA
ISO
IEA		 GO_REF:0000033
(PMID:11118295), (PMID:15304507), (PMID:16873891), (PMID:26908608), (PMID:33096711)
(PMID:19700766)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:11118295 PMID:15304507 PMID:16873891 PMID:19700766 PMID:26908608 More... GO_REF:0000033 GO_REF:0000107 NCBI chr  X:157,216,826...157,230,524
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
G Them5 thioesterase superfamily member 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:184,665,335...184,675,041
Ensembl chr 2:181,980,783...181,986,002 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        primary metabolic process 10745
          lipid metabolic process 1474
            phospholipid metabolic process 381
              glycerophospholipid metabolic process 276
                phosphatidylglycerol metabolic process 29
                  cardiolipin metabolic process 13
                    cardiolipin acyl-chain remodeling 4
paths to the root