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ONTOLOGY REPORT - ANNOTATIONS

Term:foramen ovale closure
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Accession:GO:0035922 term browser browse the term
Definition:The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.
Synonyms:exact_synonym: foramen ovale of heart closure


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foramen ovale closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO
IEA		 MGI:2445238 (PMID:10969038)
GO_REF:0000107		 RGD
Ensembl		 PMID:10969038 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO
IEA		 (PMID:19762328)
GO_REF:0000107		 RGD
Ensembl		 PMID:19762328 GO_REF:0000107 NCBI chr 8:31,475,963...31,534,051
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    developmental process 7160
      anatomical structure morphogenesis 3018
        foramen ovale closure 2
Path 2
Term Annotations click to browse term
  biological_process 20567
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            circulatory system development 1387
              heart development 750
                cardiac chamber development 204
                  cardiac septum development 132
                    cardiac septum morphogenesis 87
                      foramen ovale closure 2
paths to the root