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ONTOLOGY REPORT - ANNOTATIONS


Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation



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amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BARHL2 BarH like homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14998930) Ensembl
MGI
PMID:14998930 GO_REF:0000107 NCBI chr 4:126,030,373...126,035,662
Ensembl chr 4:126,029,437...126,036,210
JBrowse link
G BHLHE22 basic helix-loop-helix family member e22 acts_upstream_of_or_within ISO (PMID:17092954) MGI PMID:17092954 NCBI chr 4:69,801,619...69,803,375
Ensembl chr 4:69,802,200...69,803,309
JBrowse link
G FOXN4 forkhead box N4 acts_upstream_of_or_within
involved_in
ISO (PMID:15363391) MGI
UniProt
PMID:15363391 NCBI chr14:41,589,128...41,614,488 JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of
IEA
ISO
(PMID:15976303) Ensembl
MGI
PMID:15976303 GO_REF:0000107 NCBI chr 5:21,191,322...21,199,024
Ensembl chr 5:21,191,251...21,201,804
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:16038893) Ensembl
MGI
PMID:16038893 GO_REF:0000107 NCBI chr13:131,135,970...131,137,865
Ensembl chr13:131,135,725...131,138,237
JBrowse link
G IKZF1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chr 9:136,372,202...136,464,942
Ensembl chr 9:136,372,725...136,464,940
JBrowse link
G NEUROD1 neuronal differentiation 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:87,175,629...87,179,953
Ensembl chr15:87,175,765...87,179,959
JBrowse link
G NEUROD4 neuronal differentiation 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:20,046,864...20,057,380
Ensembl chr 5:20,046,937...20,059,128
JBrowse link
G PTF1A pancreas associated transcription factor 1a involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17301087) Ensembl
MGI
PMID:17301087 GO_REF:0000107 NCBI chr10:51,817,697...51,820,147
Ensembl chr10:51,817,924...51,819,960
JBrowse link
G RORB RAR related orphan receptor B involved_in ISO (PMID:23652001) UniProt PMID:23652001 NCBI chr 1:227,573,972...227,776,806
Ensembl chr 1:227,574,648...227,772,671
JBrowse link
G TGIF1 TGFB induced factor homeobox 1 acts_upstream_of ISO (PMID:18973577) MGI PMID:18973577 NCBI chr 6:103,226,395...103,234,591
Ensembl chr 6:103,226,402...103,234,610
JBrowse link
G TGIF2 TGFB induced factor homeobox 2 involved_in
acts_upstream_of
IEA
ISO
(PMID:18926818) Ensembl
MGI
PMID:18926818 GO_REF:0000107 NCBI chr17:39,840,649...39,858,162
Ensembl chr17:39,675,088...39,858,154
JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASZ1 castor zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chr 6:70,876,329...71,029,495
Ensembl chr 6:70,878,983...70,933,357
JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15976303) Ensembl
MGI
PMID:15976303 GO_REF:0000107 NCBI chr 5:21,191,322...21,199,024
Ensembl chr 5:21,191,251...21,201,804
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16038893) Ensembl
MGI
PMID:16038893 GO_REF:0000107 NCBI chr13:131,135,970...131,137,865
Ensembl chr13:131,135,725...131,138,237
JBrowse link
G POU4F2 POU class 4 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:82,044,443...82,046,377
Ensembl chr 8:82,043,643...82,047,675
JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLX1 distal-less homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:78,186,667...78,191,788
Ensembl chr15:78,185,790...78,191,226
JBrowse link
G DLX2 distal-less homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:78,200,696...78,204,264
Ensembl chr15:78,200,916...78,204,112
JBrowse link
G TGIF1 TGFB induced factor homeobox 1 acts_upstream_of_or_within ISO (PMID:18973577) MGI PMID:18973577 NCBI chr 6:103,226,395...103,234,591
Ensembl chr 6:103,226,402...103,234,610
JBrowse link
G TGIF2 TGFB induced factor homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18926818) Ensembl
MGI
PMID:18926818 GO_REF:0000107 NCBI chr17:39,840,649...39,858,162
Ensembl chr17:39,675,088...39,858,154
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18954
    developmental process 6788
      anatomical structure development 6369
        neural retina development 107
          amacrine cell differentiation 16
            negative regulation of amacrine cell differentiation 4
            positive regulation of amacrine cell differentiation 4
            regulation of amacrine cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 18954
    developmental process 6788
      anatomical structure development 6369
        multicellular organism development 5143
          system development 4487
            sensory system development 499
              visual system development 492
                eye development 490
                  camera-type eye development 440
                    retina development in camera-type eye 236
                      neural retina development 107
                        amacrine cell differentiation 16
                          negative regulation of amacrine cell differentiation 4
                          positive regulation of amacrine cell differentiation 4
                          regulation of amacrine cell differentiation + 8
paths to the root