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ONTOLOGY REPORT - ANNOTATIONS


Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation


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amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Barhl2 BarH like homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14998930) Ensembl
MGI
PMID:14998930 GO_REF:0000107 NCBI chrNW_004624742:7,027,122...7,033,342
Ensembl chrNW_004624742:7,027,069...7,034,308
JBrowse link
G Bhlhe22 basic helix-loop-helix family member e22 acts_upstream_of_or_within ISO (PMID:17092954) MGI PMID:17092954 NCBI chrNW_004624744:27,008,292...27,009,602
Ensembl chrNW_004624744:27,008,471...27,009,583
JBrowse link
G Foxn4 forkhead box N4 acts_upstream_of_or_within
involved_in
ISO (PMID:15363391) MGI
UniProt
PMID:15363391 NCBI chrNW_004624747:11,122,463...11,149,505
Ensembl chrNW_004624747:11,123,615...11,149,571
JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of ISO (PMID:15976303) MGI PMID:15976303 NCBI chrNW_004624802:12,259,971...12,269,440 JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of ISO (PMID:16038893) MGI PMID:16038893 NCBI chrNW_004624730:63,563,848...63,566,303
Ensembl chrNW_004624730:63,563,754...63,566,781
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chrNW_004624740:3,785,342...3,875,892
Ensembl chrNW_004624740:3,785,209...3,875,841
JBrowse link
G Neurod1 neuronal differentiation 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624844:3,493,819...3,497,814
Ensembl chrNW_004624844:3,494,677...3,497,759
JBrowse link
G Neurod4 neuronal differentiation 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624983:79,564...89,114
Ensembl chrNW_004624983:85,494...86,486
JBrowse link
G Ptf1a pancreas associated transcription factor 1a acts_upstream_of_or_within
involved_in
ISO (PMID:17301087)
(PMID:17075007)
MGI
UniProt
PMID:17075007 PMID:17301087 NCBI chrNW_004624796:5,548,982...5,550,563
Ensembl chrNW_004624796:5,549,184...5,550,439
JBrowse link
G Rorb RAR related orphan receptor B involved_in ISO (PMID:23652001) UniProt PMID:23652001 NCBI chrNW_004624811:2,076,474...2,281,933
Ensembl chrNW_004624811:2,076,437...2,277,040
JBrowse link
G Tgif1 TGFB induced factor homeobox 1 acts_upstream_of ISO (PMID:18973577) MGI PMID:18973577 NCBI chrNW_004624770:13,506,501...13,515,388
Ensembl chrNW_004624770:13,508,409...13,516,457
JBrowse link
G Tgif2 TGFB induced factor homeobox 2 acts_upstream_of ISO (PMID:18926818) MGI PMID:18926818 NCBI chrNW_004624842:2,909,016...2,926,555 JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chrNW_004624818:2,024,553...2,078,708
Ensembl chrNW_004624818:2,024,461...2,076,551
JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within ISO (PMID:15976303) MGI PMID:15976303 NCBI chrNW_004624802:12,259,971...12,269,440 JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:16038893) MGI PMID:16038893 NCBI chrNW_004624730:63,563,848...63,566,303
Ensembl chrNW_004624730:63,563,754...63,566,781
JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISO (PMID:21875655) UniProt PMID:21875655 NCBI chrNW_004624853:5,446,575...5,448,704
Ensembl chrNW_004624853:5,446,694...5,448,637
JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlx1 distal-less homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624787:9,514,170...9,519,309
Ensembl chrNW_004624787:9,514,573...9,519,724
JBrowse link
G Dlx2 distal-less homeobox 2 involved_in ISO (PMID:21875655) UniProt PMID:21875655 NCBI chrNW_004624787:9,528,942...9,532,252
Ensembl chrNW_004624787:9,530,034...9,533,109
JBrowse link
G Tgif1 TGFB induced factor homeobox 1 acts_upstream_of_or_within ISO (PMID:18973577) MGI PMID:18973577 NCBI chrNW_004624770:13,506,501...13,515,388
Ensembl chrNW_004624770:13,508,409...13,516,457
JBrowse link
G Tgif2 TGFB induced factor homeobox 2 acts_upstream_of_or_within ISO (PMID:18926818) MGI PMID:18926818 NCBI chrNW_004624842:2,909,016...2,926,555 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17638
    developmental process 6397
      anatomical structure development 5986
        neural retina development 102
          amacrine cell differentiation 16
            negative regulation of amacrine cell differentiation 4
            positive regulation of amacrine cell differentiation 4
            regulation of amacrine cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 17638
    developmental process 6397
      anatomical structure development 5986
        multicellular organism development 4823
          system development 4215
            sensory system development 474
              visual system development 469
                eye development 466
                  camera-type eye development 423
                    retina development in camera-type eye 225
                      neural retina development 102
                        amacrine cell differentiation 16
                          negative regulation of amacrine cell differentiation 4
                          positive regulation of amacrine cell differentiation 4
                          regulation of amacrine cell differentiation + 8
paths to the root