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ONTOLOGY REPORT - ANNOTATIONS


Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation



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amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Barhl2 BarH like homeobox 2 acts_upstream_of_or_within IDA (PMID:14998930) MGI PMID:14998930 NCBI chr 5:106,600,389...106,606,032
Ensembl chr 5:106,600,389...106,606,032
JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 acts_upstream_of_or_within IMP (PMID:17092954) MGI PMID:17092954 NCBI chr 3:18,108,489...18,111,678
Ensembl chr 3:18,108,338...18,111,681
JBrowse link
G Foxn4 forkhead box N4 acts_upstream_of_or_within
involved_in
IMP (PMID:15363391) MGI
UniProt
PMID:15363391 NCBI chr 5:114,392,225...114,412,486
Ensembl chr 5:114,392,225...114,411,868
JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of IDA (PMID:15976303) MGI PMID:15976303 NCBI chr10:128,716,393...128,727,587
Ensembl chr10:128,718,164...128,727,587
JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of IMP (PMID:16038893) MGI PMID:16038893 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within IDA (PMID:25654255) MGI PMID:25654255 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926
JBrowse link
G Miat myocardial infarction associated transcript (non-protein coding) acts_upstream_of_or_within IMP (PMID:20459797) MGI PMID:20459797 NCBI chr 5:112,361,094...112,376,814
Ensembl chr 5:112,361,094...112,377,261
JBrowse link
G Neurod1 neurogenic differentiation 1 involved_in IDA (PMID:11861467) UniProt PMID:11861467 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095
JBrowse link
G Neurod4 neurogenic differentiation 4 involved_in IDA (PMID:11861467) UniProt PMID:11861467 NCBI chr10:130,104,021...130,116,123
Ensembl chr10:130,104,021...130,116,109
JBrowse link
G Ptf1a pancreas specific transcription factor, 1a acts_upstream_of_or_within
involved_in
IMP (PMID:17301087)
(PMID:17075007)
MGI
UniProt
PMID:17075007 PMID:17301087 NCBI chr 2:19,450,474...19,452,312
Ensembl chr 2:19,450,474...19,452,312
JBrowse link
G Rorb RAR-related orphan receptor beta involved_in IMP (PMID:23652001) UniProt PMID:23652001 NCBI chr19:18,907,966...19,088,560
Ensembl chr19:18,907,969...19,088,560
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 acts_upstream_of IDA (PMID:18973577) MGI PMID:18973577 NCBI chr17:71,151,200...71,160,527
Ensembl chr17:71,151,200...71,160,541
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 acts_upstream_of IDA (PMID:18926818) MGI PMID:18926818 NCBI chr 2:156,681,737...156,697,490
Ensembl chr 2:156,681,927...156,697,490
JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 acts_upstream_of_or_within IMP (PMID:25654255) MGI PMID:25654255 NCBI chr 4:148,888,823...149,039,350
Ensembl chr 4:148,888,886...149,039,346
JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within IDA (PMID:15976303) MGI PMID:15976303 NCBI chr10:128,716,393...128,727,587
Ensembl chr10:128,718,164...128,727,587
JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within IMP (PMID:16038893) MGI PMID:16038893 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Pou4f2 POU domain, class 4, transcription factor 2 involved_in IMP (PMID:21875655) UniProt PMID:21875655 NCBI chr 8:79,159,638...79,163,276
Ensembl chr 8:79,159,639...79,163,274
JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlx1 distal-less homeobox 1 involved_in IMP (PMID:21875655) UniProt PMID:21875655 NCBI chr 2:71,358,457...71,364,325
Ensembl chr 2:71,358,457...71,364,325
JBrowse link
G Dlx2 distal-less homeobox 2 involved_in IMP (PMID:21875655) UniProt PMID:21875655 NCBI chr 2:71,373,752...71,377,095
Ensembl chr 2:71,373,752...71,377,098
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 acts_upstream_of_or_within IDA (PMID:18973577) MGI PMID:18973577 NCBI chr17:71,151,200...71,160,527
Ensembl chr17:71,151,200...71,160,541
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 acts_upstream_of_or_within IDA (PMID:18926818) MGI PMID:18926818 NCBI chr 2:156,681,737...156,697,490
Ensembl chr 2:156,681,927...156,697,490
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28633
    developmental process 7498
      anatomical structure development 6968
        neural retina development 114
          amacrine cell differentiation 17
            negative regulation of amacrine cell differentiation 4
            positive regulation of amacrine cell differentiation 4
            regulation of amacrine cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 28633
    developmental process 7498
      anatomical structure development 6968
        multicellular organism development 5545
          system development 4769
            sensory system development 517
              visual system development 510
                eye development 507
                  camera-type eye development 455
                    retina development in camera-type eye 242
                      neural retina development 114
                        amacrine cell differentiation 17
                          negative regulation of amacrine cell differentiation 4
                          positive regulation of amacrine cell differentiation 4
                          regulation of amacrine cell differentiation + 8
paths to the root