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ONTOLOGY REPORT - ANNOTATIONS


Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation


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amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BARHL2 BarH like homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14998930) Ensembl
MGI
PMID:14998930 GO_REF:0000107 NCBI chr20:42,743,465...42,757,833
Ensembl chr20:42,743,888...42,749,876
JBrowse link
G BHLHE22 basic helix-loop-helix family member e22 acts_upstream_of_or_within ISO (PMID:17092954) MGI PMID:17092954 NCBI chr 8:60,476,555...60,483,693
Ensembl chr 8:60,480,825...60,481,976
JBrowse link
G FOXN4 forkhead box N4 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15363391) MGI
Ensembl
PMID:15363391 GO_REF:0000107 NCBI chr11:104,499,654...104,536,338
Ensembl chr11:104,499,633...104,534,275
JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of
IEA
ISO
(PMID:15976303) Ensembl
MGI
PMID:15976303 GO_REF:0000107 NCBI chr11:51,693,664...51,702,781
Ensembl chr11:51,693,717...51,700,278
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:16038893) Ensembl
MGI
PMID:16038893 GO_REF:0000107 NCBI chr15:88,220,093...88,222,563
Ensembl chr15:88,220,083...88,223,243
JBrowse link
G IKZF1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chr21:8,398,902...8,500,431
Ensembl chr21:8,402,719...8,484,723
JBrowse link
G NEUROD1 neuronal differentiation 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:67,203,714...67,208,644
Ensembl chr10:67,205,141...67,206,211
JBrowse link
G NEUROD4 neuronal differentiation 4 involved_in ISO (PMID:11861467) UniProt PMID:11861467 NCBI chr11:51,112,973...51,120,862 JBrowse link
G PTF1A pancreas associated transcription factor 1a involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17301087) Ensembl
MGI
PMID:17301087 GO_REF:0000107 NCBI chr 9:22,944,122...22,965,905
Ensembl chr 9:22,964,164...22,965,565
JBrowse link
G RORB RAR related orphan receptor B involved_in ISO (PMID:23652001) UniProt PMID:23652001 NCBI chr12:85,545,609...85,735,804
Ensembl chr12:85,545,608...85,732,780
JBrowse link
G TGIF1 TGFB induced factor homeobox 1 acts_upstream_of ISO (PMID:18973577) MGI PMID:18973577 NCBI chr18:62,691,705...62,698,265 JBrowse link
G TGIF2 TGFB induced factor homeobox 2 involved_in
acts_upstream_of
IEA
ISO
(PMID:18926818) Ensembl
MGI
PMID:18926818 GO_REF:0000107 NCBI chr 2:57,437,535...57,461,975
Ensembl chr 2:57,437,623...57,462,000
JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASZ1 castor zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chr20:120,986,451...121,144,311 JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15976303) Ensembl
MGI
PMID:15976303 GO_REF:0000107 NCBI chr11:51,693,664...51,702,781
Ensembl chr11:51,693,717...51,700,278
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16038893) Ensembl
MGI
PMID:16038893 GO_REF:0000107 NCBI chr15:88,220,093...88,222,563
Ensembl chr15:88,220,083...88,223,243
JBrowse link
G POU4F2 POU class 4 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,150,105...93,160,977
Ensembl chr 7:93,150,186...93,151,857
JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLX1 distal-less homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:57,586,452...57,599,071
Ensembl chr10:57,590,838...57,595,266
JBrowse link
G DLX2 distal-less homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:57,604,989...57,609,487
Ensembl chr10:57,606,084...57,608,079
JBrowse link
G TGIF1 TGFB induced factor homeobox 1 acts_upstream_of_or_within ISO (PMID:18973577) MGI PMID:18973577 NCBI chr18:62,691,705...62,698,265 JBrowse link
G TGIF2 TGFB induced factor homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18926818) Ensembl
MGI
PMID:18926818 GO_REF:0000107 NCBI chr 2:57,437,535...57,461,975
Ensembl chr 2:57,437,623...57,462,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19803
    developmental process 6826
      anatomical structure development 6405
        neural retina development 104
          amacrine cell differentiation 16
            negative regulation of amacrine cell differentiation 4
            positive regulation of amacrine cell differentiation 4
            regulation of amacrine cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 19803
    developmental process 6826
      anatomical structure development 6405
        multicellular organism development 5154
          system development 4465
            sensory system development 499
              visual system development 493
                eye development 490
                  camera-type eye development 444
                    retina development in camera-type eye 232
                      neural retina development 104
                        amacrine cell differentiation 16
                          negative regulation of amacrine cell differentiation 4
                          positive regulation of amacrine cell differentiation 4
                          regulation of amacrine cell differentiation + 8
paths to the root