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ONTOLOGY REPORT - ANNOTATIONS


Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation



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amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BARHL2 BarH like homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14998930) Ensembl
MGI
PMID:14998930 GO_REF:0000107 NCBI chr 6:57,971,077...57,977,197
Ensembl chr 6:57,971,018...57,977,211
JBrowse link
G BHLHE22 basic helix-loop-helix family member e22 acts_upstream_of_or_within ISO (PMID:17092954) MGI PMID:17092954
G FOXN4 forkhead box N4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15363391) Ensembl
MGI
PMID:15363391 GO_REF:0000107 NCBI chr26:17,730,638...17,757,173
Ensembl chr26:17,728,878...17,755,602
JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of
IEA
ISO
(PMID:15976303) Ensembl
MGI
PMID:15976303 GO_REF:0000107 NCBI chr10:142,039...152,537
Ensembl chr10:145,036...148,373
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:16038893) Ensembl
MGI
PMID:16038893 GO_REF:0000107
G IKZF1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chr18:1,661,851...1,750,987
Ensembl chr18:1,661,690...1,770,768
JBrowse link
G NEUROD1 neuronal differentiation 1 involved_in ISO (PMID:11861467) UniProt PMID:11861467 NCBI chr36:24,853,591...24,857,886 JBrowse link
G NEUROD4 neuronal differentiation 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:384,809...396,731
Ensembl chr27:389,095...390,090
JBrowse link
G PTF1A pancreas associated transcription factor 1a involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17301087) Ensembl
MGI
PMID:17301087 GO_REF:0000107 NCBI chr 2:10,069,594...10,071,360
Ensembl chr 2:10,069,581...10,071,336
JBrowse link
G RORB RAR related orphan receptor B involved_in ISO (PMID:23652001) UniProt PMID:23652001 NCBI chr 1:83,470,569...83,666,200
Ensembl chr 1:83,476,816...83,666,061
JBrowse link
G TGIF1 TGFB induced factor homeobox 1 acts_upstream_of ISO (PMID:18973577) MGI PMID:18973577 NCBI chr 7:70,040,376...70,048,346
Ensembl chr 7:70,040,508...70,047,912
JBrowse link
G TGIF2 TGFB induced factor homeobox 2 involved_in
acts_upstream_of
IEA
ISO
(PMID:18926818) Ensembl
MGI
PMID:18926818 GO_REF:0000107 NCBI chr24:25,360,363...25,375,531
Ensembl chr24:25,364,357...25,373,302
JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASZ1 castor zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chr 2:85,194,640...85,218,068
Ensembl chr 2:85,176,161...85,232,920
JBrowse link
G GDF11 growth differentiation factor 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15976303) Ensembl
MGI
PMID:15976303 GO_REF:0000107 NCBI chr10:142,039...152,537
Ensembl chr10:145,036...148,373
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16038893) Ensembl
MGI
PMID:16038893 GO_REF:0000107
G POU4F2 POU class 4 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,030,818...45,034,446
Ensembl chr15:45,031,094...45,032,784
JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLX1 distal-less homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:16,485,158...16,489,397
Ensembl chr36:16,484,859...16,487,886
JBrowse link
G DLX2 distal-less homeobox 2 involved_in ISO (PMID:21875655) UniProt PMID:21875655 NCBI chr36:16,499,009...16,502,365
Ensembl chr36:16,484,302...16,502,510
JBrowse link
G TGIF1 TGFB induced factor homeobox 1 acts_upstream_of_or_within ISO (PMID:18973577) MGI PMID:18973577 NCBI chr 7:70,040,376...70,048,346
Ensembl chr 7:70,040,508...70,047,912
JBrowse link
G TGIF2 TGFB induced factor homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18926818) Ensembl
MGI
PMID:18926818 GO_REF:0000107 NCBI chr24:25,360,363...25,375,531
Ensembl chr24:25,364,357...25,373,302
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22121
    developmental process 6922
      anatomical structure development 6481
        neural retina development 108
          amacrine cell differentiation 16
            negative regulation of amacrine cell differentiation 4
            positive regulation of amacrine cell differentiation 4
            regulation of amacrine cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 22121
    developmental process 6922
      anatomical structure development 6481
        multicellular organism development 5245
          system development 4566
            sensory system development 511
              visual system development 505
                eye development 502
                  camera-type eye development 450
                    retina development in camera-type eye 241
                      neural retina development 108
                        amacrine cell differentiation 16
                          negative regulation of amacrine cell differentiation 4
                          positive regulation of amacrine cell differentiation 4
                          regulation of amacrine cell differentiation + 8
paths to the root