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ONTOLOGY REPORT - ANNOTATIONS


Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation


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amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Barhl2 BarH like homeobox 2 acts_upstream_of_or_within ISO (PMID:14998930) MGI PMID:14998930 NCBI chrNW_004955423:3,516,973...3,522,459
Ensembl chrNW_004955423:3,516,660...3,522,536
JBrowse link
G Bhlhe22 basic helix-loop-helix family member e22 acts_upstream_of_or_within ISO (PMID:17092954) MGI PMID:17092954 NCBI chrNW_004955444:14,458,307...14,460,441 JBrowse link
G Foxn4 forkhead box N4 acts_upstream_of_or_within
involved_in
ISO (PMID:15363391) MGI
UniProt
PMID:15363391 NCBI chrNW_004955455:9,182,405...9,210,365
Ensembl chrNW_004955455:9,183,475...9,210,506
JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of ISO (PMID:15976303) MGI PMID:15976303 NCBI chrNW_004955458:3,388,402...3,398,040
Ensembl chrNW_004955458:3,388,402...3,398,040
JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of ISO (PMID:16038893) MGI PMID:16038893 NCBI chrNW_004955420:14,565,921...14,568,447
Ensembl chrNW_004955420:14,564,283...14,568,447
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chrNW_004955456:3,617,988...3,721,791
Ensembl chrNW_004955456:3,635,380...3,721,791
JBrowse link
G Neurod1 neuronal differentiation 1 involved_in ISO (PMID:11861467) UniProt PMID:11861467 NCBI chrNW_004955403:15,595,888...15,600,040
Ensembl chrNW_004955403:15,595,888...15,600,040
JBrowse link
G Neurod4 neuronal differentiation 4 involved_in ISO (PMID:11861467) UniProt PMID:11861467 NCBI chrNW_004955458:2,138,849...2,146,636
Ensembl chrNW_004955458:2,138,849...2,146,636
JBrowse link
G Ptf1a pancreas associated transcription factor 1a involved_in
acts_upstream_of_or_within
ISO (PMID:17075007)
(PMID:17301087)
UniProt
MGI
PMID:17075007 PMID:17301087 NCBI chrNW_004955429:5,807,804...5,809,522
Ensembl chrNW_004955429:5,808,124...5,809,522
JBrowse link
G Rorb RAR related orphan receptor B involved_in ISO (PMID:23652001) UniProt PMID:23652001 NCBI chrNW_004955512:4,362,287...4,541,432
Ensembl chrNW_004955512:4,362,287...4,541,445
JBrowse link
G Tgif1 TGFB induced factor homeobox 1 acts_upstream_of ISO (PMID:18973577) MGI PMID:18973577 NCBI chrNW_004955402:7,130,809...7,138,945
Ensembl chrNW_004955402:7,129,484...7,138,340
JBrowse link
G Tgif2 TGFB induced factor homeobox 2 acts_upstream_of ISO (PMID:18926818) MGI PMID:18926818 NCBI chrNW_004955422:25,024,359...25,042,568
Ensembl chrNW_004955422:25,024,359...25,041,459
JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) MGI PMID:25654255 NCBI chrNW_004955486:2,923,239...2,975,835 JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within ISO (PMID:15976303) MGI PMID:15976303 NCBI chrNW_004955458:3,388,402...3,398,040
Ensembl chrNW_004955458:3,388,402...3,398,040
JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:16038893) MGI PMID:16038893 NCBI chrNW_004955420:14,565,921...14,568,447
Ensembl chrNW_004955420:14,564,283...14,568,447
JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISO (PMID:21875655) UniProt PMID:21875655 NCBI chrNW_004955428:2,325,775...2,329,122
Ensembl chrNW_004955428:2,324,834...2,329,205
JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlx1 distal-less homeobox 1 involved_in ISO (PMID:21875655) UniProt PMID:21875655 NCBI chrNW_004955449:2,920,705...2,924,667
Ensembl chrNW_004955449:2,920,478...2,924,667
JBrowse link
G Dlx2 distal-less homeobox 2 involved_in ISO (PMID:21875655) UniProt PMID:21875655 NCBI chrNW_004955449:2,907,502...2,909,893
Ensembl chrNW_004955449:2,907,436...2,910,816
JBrowse link
G Tgif1 TGFB induced factor homeobox 1 acts_upstream_of_or_within ISO (PMID:18973577) MGI PMID:18973577 NCBI chrNW_004955402:7,130,809...7,138,945
Ensembl chrNW_004955402:7,129,484...7,138,340
JBrowse link
G Tgif2 TGFB induced factor homeobox 2 acts_upstream_of_or_within ISO (PMID:18926818) MGI PMID:18926818 NCBI chrNW_004955422:25,024,359...25,042,568
Ensembl chrNW_004955422:25,024,359...25,041,459
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12600
    developmental process 5987
      anatomical structure development 5659
        neural retina development 97
          amacrine cell differentiation 16
            negative regulation of amacrine cell differentiation 4
            positive regulation of amacrine cell differentiation 4
            regulation of amacrine cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 12600
    developmental process 5987
      anatomical structure development 5659
        multicellular organism development 4628
          system development 4029
            sensory system development 446
              visual system development 440
                eye development 437
                  camera-type eye development 397
                    retina development in camera-type eye 215
                      neural retina development 97
                        amacrine cell differentiation 16
                          negative regulation of amacrine cell differentiation 4
                          positive regulation of amacrine cell differentiation 4
                          regulation of amacrine cell differentiation + 8
paths to the root