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ONTOLOGY REPORT - ANNOTATIONS


Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation


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amacrine cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxn4 forkhead box N4 ISO (MGI:MGI:3054139|PMID:15363391) RGD PMID:15363391 MGI:MGI:3054139 NCBI chr12:48,101,012...48,121,281
Ensembl chr12:48,101,673...48,121,270
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO (MGI:MGI:5629913|PMID:25654255) RGD PMID:25654255 MGI:MGI:5629913 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Miat myocardial infarction associated transcript ISO (MGI:MGI:4458994|PMID:20459797) RGD PMID:20459797 MGI:MGI:4458994 NCBI chr12:50,447,251...50,461,859 JBrowse link
G Neurod1 neuronal differentiation 1 ISO
ISS
(MGI:MGI:2158684|PMID:11861467)
GO_REF:0000024
RGD
UniProt
PMID:11861467 GO_REF:0000024, MGI:MGI:2158684 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
JBrowse link
G Neurod4 neuronal differentiation 4 ISO (MGI:MGI:2158684|PMID:11861467) RGD PMID:11861467 MGI:MGI:2158684 NCBI chr 7:9,699,964...9,712,067
Ensembl chr 7:9,699,961...9,711,928
JBrowse link
G Ptf1a pancreas associated transcription factor 1a ISO
ISS
(MGI:MGI:3691257|PMID:17075007)
GO_REF:0000024
RGD
UniProt
PMID:17075007 GO_REF:0000024, MGI:MGI:3691257 NCBI chr17:86,199,623...86,201,477
Ensembl chr17:86,199,623...86,201,477
JBrowse link
G Rorb RAR-related orphan receptor B ISO
ISS
(MGI:MGI:5546314|PMID:23652001)
GO_REF:0000024
RGD
UniProt
PMID:23652001 GO_REF:0000024, MGI:MGI:5546314 NCBI chr 1:234,252,757...234,442,597
Ensembl chr 1:234,252,757...234,435,839
JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 ISO MGI:MGI:3052661|MGI:MGI:4841554 (MGI:MGI:5629913|PMID:25654255) RGD PMID:25654255 MGI:MGI:5629913 NCBI chr 5:165,625,119...165,777,053
Ensembl chr 5:165,724,027...165,774,616
JBrowse link
G Pou4f2 POU class 4 homeobox 2 ISO
ISS
(MGI:MGI:5316576|PMID:21875655)
GO_REF:0000024
RGD
UniProt
PMID:21875655 GO_REF:0000024, MGI:MGI:5316576 NCBI chr19:33,160,180...33,163,821
Ensembl chr19:33,160,180...33,163,821
JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlx1 distal-less homeobox 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:5316576|PMID:21875655)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21875655 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5316576 NCBI chr 3:58,164,931...58,169,521
Ensembl chr 3:58,164,931...58,169,521
JBrowse link
G Dlx2 distal-less homeobox 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5316576|PMID:21875655)
Ensembl
UniProt
RGD
PMID:21875655 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5316576 NCBI chr 3:58,180,088...58,181,971
Ensembl chr 3:58,180,088...58,181,971
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        neural retina development 92
          amacrine cell differentiation 11
            negative regulation of amacrine cell differentiation 2
            positive regulation of amacrine cell differentiation 2
            regulation of amacrine cell differentiation + 4
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            sensory system development 470
              visual system development 465
                eye development 462
                  camera-type eye development 413
                    retina development in camera-type eye 211
                      neural retina development 92
                        amacrine cell differentiation 11
                          negative regulation of amacrine cell differentiation 2
                          positive regulation of amacrine cell differentiation 2
                          regulation of amacrine cell differentiation + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.