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ONTOLOGY REPORT - ANNOTATIONS

Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation


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amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Barhl2 BarH-like homeobox 2 acts_upstream_of_or_within ISO (PMID:14998930) RGD PMID:14998930 NCBI chr14:3,340,465...3,345,362
Ensembl chr14:3,340,465...3,345,353 		JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 acts_upstream_of_or_within ISO MGI:3707409 (PMID:17092954) RGD PMID:17092954 NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510 		JBrowse link
G Foxn4 forkhead box N4 acts_upstream_of_or_within
involved_in		 ISO MGI:3054789 (PMID:15363391) RGD PMID:15363391 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921 		JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of ISO (PMID:15976303) RGD PMID:15976303 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2149672 (PMID:16038893)		 Ensembl
RGD		 PMID:16038893 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:25654255) RGD PMID:25654255 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416 		JBrowse link
G Miat myocardial infarction associated transcript acts_upstream_of_or_within ISO (PMID:20459797) RGD PMID:20459797 NCBI chr12:44,414,620...44,429,852 JBrowse link
G Neurod1 neuronal differentiation 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11861467)		 UniProt
RGD		 PMID:11861467 GO_REF:0000024 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Neurod4 neuronal differentiation 4 involved_in ISO (PMID:11861467) RGD PMID:11861467 NCBI chr 7:7,090,048...7,102,018
Ensembl chr 7:7,090,045...7,102,030 		JBrowse link
G Ptf1a pancreas associated transcription factor 1a involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:17075007)
MGI:3701996 (PMID:17301087)		 UniProt
RGD		 PMID:17075007 PMID:17301087 GO_REF:0000024 NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135 		JBrowse link
G Rorb RAR-related orphan receptor B involved_in ISS
ISO		 GO_REF:0000024
(PMID:23652001)		 UniProt
RGD		 PMID:23652001 GO_REF:0000024 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390 		JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 acts_upstream_of ISO (PMID:18973577) RGD PMID:18973577 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 acts_upstream_of ISO (PMID:18926818) RGD PMID:18926818 NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
Ensembl chr17:145,333,418...145,348,596 		JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 acts_upstream_of_or_within ISO MGI:3052661|MGI:4841554 (PMID:25654255) RGD PMID:25654255 NCBI chr 5:159,243,965...159,393,935
Ensembl chr 5:159,243,995...159,393,400 		JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within ISO (PMID:15976303) RGD PMID:15976303 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2149672 (PMID:16038893)		 Ensembl
RGD		 PMID:16038893 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21875655)		 UniProt
RGD		 PMID:21875655 GO_REF:0000024 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327 		JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlx1 distal-less homeobox 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21875655)		 UniProt
Ensembl
RGD		 PMID:21875655 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780 		JBrowse link
G Dlx2 distal-less homeobox 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21875655)		 UniProt
Ensembl
RGD		 PMID:21875655 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597 		JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 acts_upstream_of_or_within ISO (PMID:18973577) RGD PMID:18973577 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 acts_upstream_of_or_within ISO (PMID:18926818) RGD PMID:18926818 NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
Ensembl chr17:145,333,418...145,348,596 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    developmental process 7069
      anatomical structure development 6572
        neural retina development 110
          amacrine cell differentiation 17
            negative regulation of amacrine cell differentiation 4
            positive regulation of amacrine cell differentiation 4
            regulation of amacrine cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 20075
    developmental process 7069
      anatomical structure development 6572
        multicellular organism development 5298
          system development 4583
            sensory system development 505
              visual system development 498
                eye development 495
                  camera-type eye development 443
                    retina development in camera-type eye 237
                      neural retina development 110
                        amacrine cell differentiation 17
                          negative regulation of amacrine cell differentiation 4
                          positive regulation of amacrine cell differentiation 4
                          regulation of amacrine cell differentiation + 8
paths to the root