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ONTOLOGY REPORT - ANNOTATIONS


Term:amacrine cell differentiation
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Accession:GO:0035881 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms:exact_synonym: amacrine neuron differentiation



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amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxn4 forkhead box N4 involved_in ISO (MGI:3054139|PMID:15363391) RGD PMID:15363391 MGI:3054139 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (MGI:5629913|PMID:25654255) RGD PMID:25654255 MGI:5629913 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Miat myocardial infarction associated transcript acts_upstream_of_or_within ISO (MGI:4458994|PMID:20459797) RGD PMID:20459797 MGI:4458994 NCBI chr12:44,414,620...44,429,852 JBrowse link
G Neurod1 neuronal differentiation 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:2158684|PMID:11861467)
UniProt
RGD
PMID:11861467 GO_REF:0000024 MGI:2158684 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
JBrowse link
G Neurod4 neuronal differentiation 4 involved_in ISO (MGI:2158684|PMID:11861467) RGD PMID:11861467 MGI:2158684 NCBI chr 7:7,090,048...7,102,018
Ensembl chr 7:7,090,045...7,102,030
JBrowse link
G Ptf1a pancreas associated transcription factor 1a involved_in ISS
ISO
GO_REF:0000024
(MGI:3691257|PMID:17075007)
UniProt
RGD
PMID:17075007 GO_REF:0000024 MGI:3691257 NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135
JBrowse link
G Rorb RAR-related orphan receptor B involved_in ISS
ISO
GO_REF:0000024
(MGI:5546314|PMID:23652001)
UniProt
RGD
PMID:23652001 GO_REF:0000024 MGI:5546314 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390
JBrowse link
negative regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 acts_upstream_of_or_within ISO MGI:3052661|MGI:4841554 (MGI:5629913|PMID:25654255) RGD PMID:25654255 MGI:5629913 NCBI chr 5:159,243,965...159,393,935
Ensembl chr 5:159,243,995...159,393,400
JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5316576|PMID:21875655)
UniProt
RGD
PMID:21875655 GO_REF:0000024 MGI:5316576 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327
JBrowse link
positive regulation of amacrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlx1 distal-less homeobox 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5316576|PMID:21875655)
UniProt
Ensembl
RGD
PMID:21875655 GO_REF:0000024 GO_REF:0000107 MGI:5316576 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780
JBrowse link
G Dlx2 distal-less homeobox 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5316576|PMID:21875655)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:21875655 GO_REF:0000024 GO_REF:0000107 MGI:5316576 NCBI chr 3:56,371,347...56,373,230
Ensembl chr 3:56,370,483...56,373,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    developmental process 6920
      anatomical structure development 6337
        neural retina development 93
          amacrine cell differentiation 11
            negative regulation of amacrine cell differentiation 2
            positive regulation of amacrine cell differentiation 2
            regulation of amacrine cell differentiation + 4
Path 2
Term Annotations click to browse term
  biological_process 19541
    developmental process 6920
      anatomical structure development 6337
        multicellular organism development 5765
          system development 5408
            sensory system development 477
              visual system development 472
                eye development 469
                  camera-type eye development 420
                    retina development in camera-type eye 215
                      neural retina development 93
                        amacrine cell differentiation 11
                          negative regulation of amacrine cell differentiation 2
                          positive regulation of amacrine cell differentiation 2
                          regulation of amacrine cell differentiation + 4
paths to the root