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ONTOLOGY REPORT - ANNOTATIONS


Term:alphav-beta3 integrin-IGF-1-IGF1R complex
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Accession:GO:0035867 term browser browse the term
Definition:A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.


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alphav-beta3 integrin-IGF-1-IGF1R complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1 insulin-like growth factor 1 part_of ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19578119)
UniProt
Ensembl
RGD
PMID:19578119 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor part_of IEA
ISO
GO_REF:0000107
(PMID:19578119)
Ensembl
RGD
PMID:19578119 GO_REF:0000107 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Itgav integrin subunit alpha V part_of ISO (PMID:19578119) RGD PMID:19578119 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Itgb3 integrin subunit beta 3 part_of ISO (PMID:19578119) RGD PMID:19578119 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20137
    protein-containing complex 6038
      membrane protein complex 1243
        plasma membrane protein complex 564
          alphav-beta3 integrin-IGF-1-IGF1R complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20137
    cellular anatomical entity 19837
      membrane 10007
        plasma membrane 6229
          plasma membrane protein complex 564
            alphav-beta3 integrin-IGF-1-IGF1R complex 4
paths to the root