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ONTOLOGY REPORT - ANNOTATIONS

Term:glial cell-derived neurotrophic factor receptor signaling pathway
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Accession:GO:0035860 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to a glial cell-derived neurotrophic factor receptor.
Synonyms:exact_synonym: GDNF receptor signaling pathway;   glial cell line-derived neurotrophic factor receptor signalling pathway;   glial cell-derived neurotrophic factor receptor signalling pathway


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glial cell-derived neurotrophic factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Artn artemin involved_in ISO
IEA		 (PMID:31535977)
GO_REF:0000107		 RGD
Ensembl		 PMID:31535977 GO_REF:0000107 NCBI chr 5:136,750,188...136,755,645
Ensembl chr 5:131,464,756...131,468,025 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:25242331), (PMID:31535977)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:25242331 PMID:31535977 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 involved_in ISS
IEA
ISO
IDA		 GO_REF:0000024
GO_REF:0000107
(PMID:31535977)
PMID:25242331		 UniProt
Ensembl
RGD		 PMID:31535977 PMID:25242331 GO_REF:0000024 GO_REF:0000107, RGD:401966874 NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Gfra2 GDNF family receptor alpha 2 involved_in ISO (PMID:29414779), (PMID:31535977) RGD PMID:29414779 PMID:31535977 NCBI chr15:52,351,499...52,443,369
Ensembl chr15:45,941,828...46,033,714 		JBrowse link
G Gfra3 GDNF family receptor alpha 3 involved_in ISO
IEA		 (PMID:31535977)
GO_REF:0000107		 RGD
Ensembl		 PMID:31535977 GO_REF:0000107 NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105 		JBrowse link
G Gfra4 GDNF family receptor alpha 4 involved_in ISO (PMID:11116144) RGD PMID:11116144 NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329 		JBrowse link
G Nrtn neurturin involved_in ISO (PMID:29414779), (PMID:31535977)
(PMID:8945474)		 RGD PMID:8945474 PMID:29414779 PMID:31535977 NCBI chr 9:1,669,099...1,674,957
Ensembl chr 9:1,581,975...1,583,102 		JBrowse link
G Pspn persephin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:11116144)		 UniProt
Ensembl
RGD		 PMID:11116144 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:1,927,911...1,930,785
Ensembl chr 9:1,840,896...1,854,327 		JBrowse link
G Ret ret proto-oncogene involved_in ISS
ISO		 GO_REF:0000024
(PMID:24560924), (PMID:25242331), (PMID:28953886), (PMID:31535977)		 UniProt
RGD		 PMID:24560924 PMID:25242331 PMID:28953886 PMID:31535977 GO_REF:0000024 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Sulf1 sulfatase 1 involved_in IEA
ISO
ISS		 GO_REF:0000104
(PMID:17720696)
GO_REF:0000024		 UniProt
RGD		 PMID:17720696 GO_REF:0000024 GO_REF:0000104 NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Sulf2 sulfatase 2 involved_in ISO
IEA		 (PMID:17720696)
GO_REF:0000107
GO_REF:0000104		 RGD
Ensembl
UniProt		 PMID:17720696 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
GDF15-GFRAL signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdf15 growth differentiation factor 15 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28953886), (PMID:31535977), (PMID:35177851)
GO_REF:0000107
(PMID:31875646), (PMID:32723474), (PMID:33593916), (PMID:35202387), (PMID:37380764)		 UniProt
RGD
Ensembl		 PMID:28953886 PMID:31535977 PMID:31875646 PMID:32723474 PMID:33593916 More... GO_REF:0000024 GO_REF:0000107 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gfral GDNF family receptor alpha like involved_in ISS
ISO		 GO_REF:0000024
(PMID:31875646), (PMID:32723474), (PMID:33593916), (PMID:35202387)
(PMID:28953886), (PMID:31535977), (PMID:35177851)		 UniProt
RGD		 PMID:28953886 PMID:31535977 PMID:31875646 PMID:32723474 PMID:33593916 More... GO_REF:0000024 NCBI chr 8:85,798,337...85,843,705
Ensembl chr 8:76,918,657...76,959,425 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:31535977) RGD PMID:31535977 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
negative regulation of GDF15-GFRAL signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp14 matrix metallopeptidase 14 involved_in ISO
IEA		 (PMID:35177851)
GO_REF:0000107		 RGD
Ensembl		 PMID:35177851 GO_REF:0000107 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISO
IEA		 (PMID:19112489)
GO_REF:0000107		 RGD
Ensembl		 PMID:19112489 GO_REF:0000107 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      signal transduction 7313
        cell surface receptor signaling pathway 2915
          enzyme-linked receptor protein signaling pathway 1073
            cell surface receptor protein tyrosine kinase signaling pathway 681
              glial cell-derived neurotrophic factor receptor signaling pathway 15
                GDF15-GFRAL signaling pathway + 4
                glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation + 1
Path 2
Term Annotations click to browse term
  biological_process 20567
    biological regulation 13841
      regulation of biological process 13403
        signaling 7874
          signal transduction 7313
            cell surface receptor signaling pathway 2915
              enzyme-linked receptor protein signaling pathway 1073
                cell surface receptor protein tyrosine kinase signaling pathway 681
                  glial cell-derived neurotrophic factor receptor signaling pathway 15
                    GDF15-GFRAL signaling pathway + 4
                    glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation + 1
paths to the root