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ONTOLOGY REPORT - ANNOTATIONS

Term:Seh1-associated complex
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Accession:GO:0035859 term browser browse the term
Definition:A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p.
Comment:The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ; GO:1990131.
Synonyms:exact_synonym: GATOR complex;   SEA complex


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Seh1-associated complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wdr59 WD repeat domain 59 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:39,416,432...39,483,773
Ensembl chr19:39,416,429...39,483,698 		JBrowse link
GATOR1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit part_of IBA
ISO		 GO_REF:0000033
(PMID:25263562), (PMID:29590090), (PMID:35338845)		 GO_Central
RGD		 PMID:25263562 PMID:29590090 PMID:35338845 GO_REF:0000033 NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794 		JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit part_of IBA
ISO		 GO_REF:0000033
(PMID:25263562), (PMID:29590090), (PMID:35338845)		 GO_Central
RGD		 PMID:25263562 PMID:29590090 PMID:35338845 GO_REF:0000033 NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996 		JBrowse link
G Nprl3 NPR3-like, GATOR1 complex subunit part_of IBA
ISO		 GO_REF:0000033
(PMID:25263562), (PMID:29590090), (PMID:35338845)		 GO_Central
RGD		 PMID:25263562 PMID:29590090 PMID:35338845 GO_REF:0000033 NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810 		JBrowse link
G Rraga Ras-related GTP binding A part_of
located_in		 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:25936802)		 Ensembl
UniProt
RGD		 PMID:25936802 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510 		JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex located_in ISO (PMID:28199306), (PMID:28199315) RGD PMID:28199306 PMID:28199315 NCBI chr 5:131,897,250...131,943,953
Ensembl chr 5:131,897,275...131,943,904 		JBrowse link
GATOR2 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 located_in ISS
ISO		 GO_REF:0000024
(PMID:26972053)		 UniProt
RGD		 PMID:26972053 GO_REF:0000024 NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548 		JBrowse link
G Castor2 cytosolic arginine sensor for mTORC1 subunit 2 located_in ISO (PMID:26972053) RGD PMID:26972053 NCBI chr12:22,577,504...22,620,182
Ensembl chr12:22,577,512...22,620,182 		JBrowse link
G Mios meiosis regulator for oocyte development part_of ISO (PMID:35831510), (PMID:36528027) RGD PMID:35831510 PMID:36528027 NCBI chr 4:36,263,419...36,289,546
Ensembl chr 4:36,263,968...36,289,544 		JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component part_of ISS
ISO		 GO_REF:0000024
(PMID:35831510), (PMID:36528027)		 UniProt
RGD		 PMID:35831510 PMID:36528027 GO_REF:0000024 NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173 		JBrowse link
G Seh1l SEH1-like nucleoporin part_of ISO (PMID:35831510), (PMID:36528027) RGD PMID:35831510 PMID:36528027 NCBI chr18:61,346,986...61,369,987 JBrowse link
G Sesn1 sestrin 1 located_in ISO (PMID:25263562), (PMID:26449471) RGD PMID:25263562 PMID:26449471 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sesn3 sestrin 3 located_in ISO (PMID:25263562), (PMID:26449471) RGD PMID:25263562 PMID:26449471 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842 		JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex located_in ISO (PMID:28199306), (PMID:28199315) RGD PMID:28199306 PMID:28199315 NCBI chr 5:131,897,250...131,943,953
Ensembl chr 5:131,897,275...131,943,904 		JBrowse link
G Wdr24 WD repeat domain 24 part_of IBA
ISO		 GO_REF:0000033
(PMID:35831510), (PMID:36528027)		 GO_Central
RGD		 PMID:35831510 PMID:36528027 GO_REF:0000033 NCBI chr10:14,844,089...14,848,871
Ensembl chr10:14,843,728...14,848,864 		JBrowse link
G Wdr59 WD repeat domain 59 part_of ISO (PMID:35831510), (PMID:36528027) RGD PMID:35831510 PMID:36528027 NCBI chr19:39,416,432...39,483,773
Ensembl chr19:39,416,429...39,483,698 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20814
    protein-containing complex 6438
      Seh1-associated complex 14
        GATOR1 complex 5
        GATOR2 complex 10
paths to the root