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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mitochondrial membrane permeability
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Accession:GO:0035794 term browser browse the term
Definition:Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
Synonyms:exact_synonym: positive regulation of transport across mitochondrial membrane
 narrow_synonym: MPT;   mitochondrial membrane permeability transition;   mitochondrial membrane permeabilization;   mitochondrial permeability transition



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positive regulation of mitochondrial membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3l BCL2 interacting protein 3 like IMP RGD PMID:26512955 RGD:11564338 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Hebp2 heme binding protein 2 involved_in ISO (PMID:17098234) RGD PMID:17098234 NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IMP RGD PMID:21297023 RGD:6771330 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:2145814 (MGI:5431269|PMID:22726440) RGD PMID:22726440 MGI:5431269 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
mitochondrial outer membrane permeabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO MGI:1929260 (MGI:5566519|PMID:20436477) RGD PMID:20436477 MGI:5566519 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 involved_in ISO
ISS
(PMID:18188704) RGD PMID:18188704 PMID:18188704 RGD:8553738 NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in IBA
ISO
PMID:21873635
(PMID:18371312)
RGD PMID:18371312 PMID:21873635 RGD:13792537 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within ISO (MGI:2158099|PMID:11700312) RGD PMID:11700312 MGI:2158099 NCBI chr 3:154,335,558...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G LOC102548901 protein Bop-like involved_in ISO (PMID:23055042) RGD PMID:23055042
G Rhot1 ras homolog family member T1 involved_in ISO (PMID:12482879) RGD PMID:12482879 NCBI chr10:65,198,700...65,262,807
Ensembl chr10:65,170,560...65,262,804
JBrowse link
G Rhot2 ras homolog family member T2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12482879)
UniProt
RGD
PMID:12482879 GO_REF:0000024 NCBI chr10:14,858,954...14,864,751
Ensembl chr10:14,858,956...14,864,751
JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO
ISS
(PMID:31015432)
GO_REF:0000024
RGD
UniProt
PMID:31015432 GO_REF:0000024 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
mitochondrial outer membrane permeabilization involved in programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppif peptidylprolyl isomerase F involved_in ISO
ISS
(PMID:26387735)
GO_REF:0000024
RGD
UniProt
PMID:26387735 GO_REF:0000024 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Spg7 SPG7 matrix AAA peptidase subunit, paraplegin involved_in IMP PMID:26387735 UniProt PMID:26387735 RGD:13441202 NCBI chr19:51,117,045...51,151,228
Ensembl chr19:51,117,057...51,150,484
JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:18371312)
Ensembl
UniProt
RGD
PMID:18371312 GO_REF:0000024 GO_REF:0000107 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:9393856)
(PMID:15901672), (PMID:9393856)
RGD PMID:9393856 PMID:15901672 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5796062|PMID:27098698) RGD PMID:27098698 MGI:5796062 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649
JBrowse link
G Slc25a31 solute carrier family 25 member 31 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:123,695,387...123,711,275
Ensembl chr 2:123,695,408...123,710,795
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19154410)
UniProt
RGD
PMID:19154410 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Slc35f6 solute carrier family 35, member F6 involved_in ISS
ISO
GO_REF:0000024
(PMID:19154410)
UniProt
RGD
PMID:19154410 GO_REF:0000024 NCBI chr 6:25,725,822...25,737,720
Ensembl chr 6:25,725,819...25,737,730
JBrowse link
G Tmem14a transmembrane protein 14A involved_in ISO (PMID:21723035) RGD PMID:21723035 NCBI chr 9:23,640,594...23,652,379
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463
JBrowse link
positive regulation of mitochondrial membrane permeability involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO
ISS
(PMID:22304920)
GO_REF:0000024
RGD
UniProt
PMID:22304920 GO_REF:0000024 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1197519 (MGI:3581932|PMID:15967824) RGD PMID:15967824 MGI:3581932 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within ISO MGI:99702 (MGI:3581932|PMID:15967824) RGD PMID:15967824 MGI:3581932 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Mir29a microRNA 29a involved_in ISO (PMID:20041405) RGD PMID:20041405 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:20041405) RGD PMID:20041405 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:20041405) RGD PMID:20041405 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Stpg1 sperm-tail PG-rich repeat containing 1 involved_in IBA
ISO
PMID:21873635
(PMID:23028632)
RGD PMID:23028632 PMID:21873635 RGD:13792537 NCBI chr 5:147,717,084...147,769,792
Ensembl chr 5:147,726,646...147,769,788
JBrowse link
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5796067|PMID:26949185)
UniProt
RGD
PMID:26949185 GO_REF:0000024 MGI:5796067 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO (PMID:26666268), (PMID:30092269) RGD PMID:26666268 PMID:30092269 NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:5514334|PMID:16543145)
UniProt
RGD
PMID:16543145 GO_REF:0000024 MGI:5514334 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:5514334|PMID:16543145)
UniProt
RGD
PMID:16543145 GO_REF:0000024 MGI:5514334 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO UniProtKB:Q9HD36 (PMID:19255499) RGD PMID:19255499 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO (PMID:15034012) RGD PMID:15034012 NCBI chr 6:131,705,312...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:12,615,470...12,623,615
Ensembl chr10:12,615,190...12,623,615
JBrowse link
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbc3 Bcl-2 binding component 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:17024184)
MGI:2681654 (MGI:3804133|PMID:16705087)
RGD PMID:16705087 PMID:17024184 PMID:21873635 MGI:3804133, RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO MGI:2678372 (MGI:2675761|PMID:12952892) RGD PMID:12952892 MGI:2675761 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 acts_upstream_of_or_within ISO (MGI:3607027|PMID:16227588) RGD PMID:16227588 MGI:3607027 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1857429 (MGI:2675761|PMID:12952892) RGD PMID:12952892 MGI:2675761 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 acts_upstream_of ISO MGI:2681654 (MGI:3804133|PMID:16705087) RGD PMID:16705087 MGI:3804133 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:18591963) RGD PMID:18591963 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Tmem102 transmembrane protein 102 involved_in ISO (PMID:17828305) RGD PMID:17828305 NCBI chr10:54,523,901...54,525,999
Ensembl chr10:54,523,585...54,525,990
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18872
    biological regulation 13378
      regulation of biological quality 4172
        regulation of membrane permeability 81
          regulation of mitochondrial membrane permeability 62
            positive regulation of mitochondrial membrane permeability 48
              mitochondrial outer membrane permeabilization involved in programmed cell death + 45
              positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 18872
    cellular process 17581
      cellular component organization or biogenesis 6570
        cellular component organization 6338
          organelle organization 3922
            mitochondrion organization 580
              mitochondrial membrane organization 113
                regulation of mitochondrial membrane permeability 62
                  positive regulation of mitochondrial membrane permeability 48
                    mitochondrial outer membrane permeabilization involved in programmed cell death + 45
                    positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway + 11
paths to the root