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ONTOLOGY REPORT - ANNOTATIONS

Term:platelet-derived growth factor receptor-beta signaling pathway
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Accession:GO:0035791 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-beta signaling pathway;   PDGFR-beta signaling pathway;   betaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-beta signalling pathway

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platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669 		JBrowse link
G Alk ALK receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936493:3,624,288...3,671,567
Ensembl chrNW_004936493:3,028,608...3,671,874 		JBrowse link
G Axl AXL receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936661:3,658,140...3,687,290
Ensembl chrNW_004936661:3,657,831...3,687,816 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24520051) UniProt PMID:24520051 NCBI chrNW_004936473:23,756,291...23,940,966
Ensembl chrNW_004936473:23,755,627...23,900,014 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936837:523,227...538,799
Ensembl chrNW_004936837:523,266...538,833 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139 		JBrowse link
G Egfr epidermal growth factor receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528 		JBrowse link
G Epha1 EPH receptor A1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936527:833,578...847,824
Ensembl chrNW_004936527:830,112...848,512 		JBrowse link
G Epha2 EPH receptor A2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936474:3,648,395...3,673,856
Ensembl chrNW_004936474:3,648,550...3,673,861 		JBrowse link
G Epha3 EPH receptor A3 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936610:462,842...799,466
Ensembl chrNW_004936610:462,853...799,364 		JBrowse link
G Epha4 EPH receptor A4 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936569:3,539,269...3,670,322
Ensembl chrNW_004936569:3,540,053...3,670,348 		JBrowse link
G Epha5 EPH receptor A5 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936582:2,503,546...2,832,950
Ensembl chrNW_004936582:2,505,145...2,830,014 		JBrowse link
G Epha6 EPH receptor A6 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936666:2,280,811...3,063,601
Ensembl chrNW_004936666:2,282,000...3,061,944 		JBrowse link
G Epha7 EPH receptor A7 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936812:698,548...865,589
Ensembl chrNW_004936812:698,533...865,481 		JBrowse link
G Epha8 EPH receptor A8 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936474:7,928,700...7,981,961
Ensembl chrNW_004936474:7,928,700...7,981,962 		JBrowse link
G Ephb1 EPH receptor B1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936529:8,006,780...8,261,923
Ensembl chrNW_004936529:7,839,768...8,261,942 		JBrowse link
G Ephb2 EPH receptor B2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936474:8,109,800...8,203,106
Ensembl chrNW_004936474:8,109,031...8,203,106 		JBrowse link
G Ephb3 EPH receptor B3 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936578:5,286,580...5,297,369
Ensembl chrNW_004936578:5,287,340...5,298,142 		JBrowse link
G Ephb4 EPH receptor B4 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936543:794,837...811,637
Ensembl chrNW_004936543:794,725...811,637 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936646:497,783...515,247
Ensembl chrNW_004936646:498,749...513,297 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936477:21,591,772...21,606,289
Ensembl chrNW_004936477:21,591,792...21,606,296 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758 		JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936472:23,442,946...23,617,523
Ensembl chrNW_004936472:23,440,088...23,617,041 		JBrowse link
G Flt3 fms related receptor tyrosine kinase 3 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936472:23,169,967...23,239,178
Ensembl chrNW_004936472:23,170,470...23,256,904 		JBrowse link
G Flt4 fms related receptor tyrosine kinase 4 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936739:240,572...281,925
Ensembl chrNW_004936739:236,510...281,729 		JBrowse link
G Igf1r insulin like growth factor 1 receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925 		JBrowse link
G Insr insulin receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936588:4,345,306...4,453,380
Ensembl chrNW_004936588:4,345,306...4,453,668 		JBrowse link
G Insrr insulin receptor related receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936580:5,982,259...5,999,994
Ensembl chrNW_004936580:5,983,006...5,999,994 		JBrowse link
G Kdr kinase insert domain receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936482:17,162,854...17,238,319
Ensembl chrNW_004936482:17,162,950...17,238,274 		JBrowse link
G LOC101955809 vascular endothelial growth factor receptor kdr-like involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936635:4,024,882...4,313,912 JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:18586678
(PMID:18586678)		 MGI
Ensembl		 PMID:18586678 GO_REF:0000107 RGD:14390060 NCBI chrNW_004936575:2,526,067...2,533,996
Ensembl chrNW_004936575:2,524,342...2,533,559 		JBrowse link
G Ltk leukocyte receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936471:4,849,261...4,857,892
Ensembl chrNW_004936471:4,849,219...4,855,678 		JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936783:607,425...704,879
Ensembl chrNW_004936783:607,382...704,889 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179 		JBrowse link
G Mst1r macrophage stimulating 1 receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936529:1,494,748...1,509,925
Ensembl chrNW_004936529:1,495,059...1,509,901 		JBrowse link
G Musk muscle associated receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936559:2,387,019...2,486,685
Ensembl chrNW_004936559:2,387,027...2,486,552 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936580:6,002,168...6,021,690
Ensembl chrNW_004936580:6,002,120...6,021,709 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936680:267,850...621,467
Ensembl chrNW_004936680:267,596...615,928 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936483:13,912,904...14,291,881
Ensembl chrNW_004936483:13,909,109...14,291,887 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936482:16,804,129...16,853,539
Ensembl chrNW_004936482:16,807,569...16,853,587 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in IEA GOC
Ensembl		 GO_REF:0000107 GO_REF:0000108 NCBI chrNW_004936504:4,762,251...4,799,789
Ensembl chrNW_004936504:4,762,184...4,799,829 		JBrowse link
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:4,065,455...4,083,847
Ensembl chrNW_004936514:4,068,238...4,084,009 		JBrowse link
G Ret ret proto-oncogene involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602 		JBrowse link
G Ros1 ROS proto-oncogene 1, receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936658:382,025...506,818
Ensembl chrNW_004936658:382,261...506,818 		JBrowse link
G Tek TEK receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936611:2,420,176...2,531,726
Ensembl chrNW_004936611:2,420,172...2,531,722 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin like and EGF like domains 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936474:24,709,424...24,729,246
Ensembl chrNW_004936474:24,709,424...24,729,245 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936471:4,893,185...4,910,779
Ensembl chrNW_004936471:4,893,078...4,910,859 		JBrowse link
negative regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glrx glutaredoxin ISO RGD PMID:16893901 RGD:9686048 NCBI chrNW_004936523:7,535,650...7,544,339
Ensembl chrNW_004936523:7,535,857...7,541,864 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:19742316) BHF-UCL PMID:19742316 NCBI chrNW_004936646:1,326,900...1,407,236
Ensembl chrNW_004936646:1,327,374...1,406,456 		JBrowse link
G Myocd myocardin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:5,256,615...5,356,563
Ensembl chrNW_004936595:5,256,785...5,351,723 		JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936626:2,390,004...2,472,039
Ensembl chrNW_004936626:2,389,868...2,445,927 		JBrowse link
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936754:808,894...828,554
Ensembl chrNW_004936754:808,213...828,613 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO (PMID:19019919) UniProt PMID:19019919 NCBI chrNW_004936504:4,762,251...4,799,789
Ensembl chrNW_004936504:4,762,184...4,799,829 		JBrowse link
positive regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hip1 huntingtin interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:2,496,301...2,569,019
Ensembl chrNW_004936543:2,522,154...2,565,376 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:1,778,862...1,804,071
Ensembl chrNW_004936558:1,778,888...1,791,610 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23651497) Ensembl
MGI		 PMID:23651497 GO_REF:0000107 NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483 		JBrowse link
regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lox lysyl oxidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21665949) Ensembl
MGI		 PMID:21665949 GO_REF:0000107 NCBI chrNW_004936575:2,526,067...2,533,996
Ensembl chrNW_004936575:2,524,342...2,533,559 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17407
    cellular process 17010
      signal transduction 5707
        cell surface receptor signaling pathway 2553
          enzyme-linked receptor protein signaling pathway 938
            cell surface receptor protein tyrosine kinase signaling pathway 614
              platelet-derived growth factor receptor signaling pathway 113
                platelet-derived growth factor receptor-beta signaling pathway 62
                  VEGF-activated platelet-derived growth factor receptor-beta signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-beta signaling pathway 4
                  positive regulation of platelet-derived growth factor receptor-beta signaling pathway 3
                  regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway + 3
                  regulation of platelet-derived growth factor receptor-beta signaling pathway + 8
Path 2
Term Annotations click to browse term
  biological_process 17407
    biological regulation 11406
      regulation of biological process 11039
        signaling 6201
          signal transduction 5707
            cell surface receptor signaling pathway 2553
              enzyme-linked receptor protein signaling pathway 938
                cell surface receptor protein tyrosine kinase signaling pathway 614
                  platelet-derived growth factor receptor signaling pathway 113
                    platelet-derived growth factor receptor-beta signaling pathway 62
                      VEGF-activated platelet-derived growth factor receptor-beta signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-beta signaling pathway 4
                      positive regulation of platelet-derived growth factor receptor-beta signaling pathway 3
                      regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway + 3
                      regulation of platelet-derived growth factor receptor-beta signaling pathway + 8
paths to the root