ONTOLOGY REPORT - ANNOTATIONS
Term: platelet-derived growth factor receptor-beta signaling pathway
Accession: GO:0035791
browse the term
Definition: The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms: exact_synonym: PDGF receptor-beta signaling pathway; PDGFR-beta signaling pathway; betaPDGF receptor signaling pathway; platelet-derived growth factor receptor-beta signalling pathway
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ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307
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ALK
ALK receptor tyrosine kinase
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr17:23,010,308...23,688,841
Ensembl chr17:23,010,308...23,688,841
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CLASP2
cytoplasmic linker associated protein 2
involved_in
ISO
(PMID:24520051)
UniProt
PMID:24520051
NCBI chr23:3,261,778...3,423,698
Ensembl chr23:3,246,522...3,421,716
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EPHA2
EPH receptor A2
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr 2:81,534,130...81,561,722
Ensembl chr 2:81,534,125...81,561,725
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ERBB2
erb-b2 receptor tyrosine kinase 2
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294
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FGFR2
fibroblast growth factor receptor 2
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621
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FLT3
fms related receptor tyrosine kinase 3
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
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KDR
kinase insert domain receptor
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042
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KIT
KIT proto-oncogene, receptor tyrosine kinase
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
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LOX
lysyl oxidase
acts_upstream_of_or_within involved_in
ISO IBA IEA
PMID:18586678 (PMID:18586678)
MGI GO_Central Ensembl
PMID:18586678
GO_REF:0000033 GO_REF:0000107 RGD:14390060
NCBI chr11:12,023,645...12,040,015
Ensembl chr11:12,027,250...12,039,819
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MET
MET proto-oncogene, receptor tyrosine kinase
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027
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PDGFRA
platelet derived growth factor receptor alpha
involved_in
IEA
GOC
GO_REF:0000108
NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278
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PDGFRB
platelet derived growth factor receptor beta
involved_in
IEA
GOC Ensembl
GO_REF:0000107 GO_REF:0000108
NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283
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PTPN1
protein tyrosine phosphatase non-receptor type 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720
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GLRX
glutaredoxin
ISO
RGD
PMID:16893901
RGD:9686048
NCBI chr 3:13,795,609...13,804,732
Ensembl chr 3:13,795,817...13,803,895
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LRP1
LDL receptor related protein 1
involved_in
ISO
(PMID:19742316)
BHF-UCL
PMID:19742316
NCBI chr10:1,260,256...1,341,705
Ensembl chr10:1,260,719...1,352,271
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MYOCD
myocardin
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327
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PTPN2
protein tyrosine phosphatase non-receptor type 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719
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PDGFA
platelet derived growth factor subunit A
involved_in
ISO
(PMID:19019919)
UniProt
PMID:19019919
NCBI chr 6:16,271,082...16,293,246
Ensembl chr 6:16,270,104...16,292,396
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PDGFB
platelet derived growth factor subunit B
involved_in
ISS IEA
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746
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PDGFRB
platelet derived growth factor receptor beta
involved_in
ISO
(PMID:19019919)
UniProt
PMID:19019919
NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283
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HIP1
huntingtin interacting protein 1
involved_in
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 6:6,957,760...7,115,676
Ensembl chr 6:6,961,053...7,115,618
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HIP1R
huntingtin interacting protein 1 related
involved_in
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr26:6,623,583...6,639,107
Ensembl chr26:6,624,791...6,637,659
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SRC
SRC proto-oncogene, non-receptor tyrosine kinase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:23651497)
Ensembl MGI
PMID:23651497
GO_REF:0000107
NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
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LOX
lysyl oxidase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:21665949)
Ensembl MGI
PMID:21665949
GO_REF:0000107
NCBI chr11:12,023,645...12,040,015
Ensembl chr11:12,027,250...12,039,819
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