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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet-derived growth factor receptor-beta signaling pathway
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Accession:GO:0035791 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-beta signaling pathway;   PDGFR-beta signaling pathway;   betaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-beta signalling pathway


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platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:24520051) UniProt PMID:24520051 NCBI chrNW_004955513:652,048...799,182
Ensembl chrNW_004955513:653,252...799,239
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24520051) UniProt PMID:24520051 NCBI chrNW_004955421:767,648...957,160
Ensembl chrNW_004955421:767,210...897,457
JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within ISO PMID:18586678
(PMID:18586678)
MGI PMID:18586678 RGD:14390060 NCBI chrNW_004955521:178,290...193,926
Ensembl chrNW_004955521:185,792...193,926
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO (PMID:2554309), (PMID:26599395) UniProt PMID:2554309 PMID:26599395 NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587
JBrowse link
G Ptpn1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:14966296) UniProt PMID:14966296 NCBI chrNW_004955445:7,754,313...7,819,229
Ensembl chrNW_004955445:7,754,319...7,819,275
JBrowse link
negative regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glrx glutaredoxin ISO RGD PMID:16893901 RGD:9686048 NCBI chrNW_004955418:16,747,709...16,754,718
Ensembl chrNW_004955418:16,747,776...16,752,858
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:19742316) BHF-UCL PMID:19742316 NCBI chrNW_004955458:4,861,431...4,941,939
Ensembl chrNW_004955458:4,861,431...4,941,146
JBrowse link
G Myocd myocardin involved_in ISO (PMID:23825366) BHF-UCL PMID:23825366 NCBI chrNW_004955467:4,653,065...4,743,438
Ensembl chrNW_004955467:4,656,380...4,743,110
JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (PMID:14966296) UniProt PMID:14966296 NCBI chrNW_004955402:771,410...846,671 JBrowse link
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in ISO (PMID:19019919) UniProt PMID:19019919 NCBI chrNW_004955460:8,328,400...8,346,755
Ensembl chrNW_004955460:8,326,891...8,346,550
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO (PMID:19019919) UniProt PMID:19019919 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO (PMID:19019919) UniProt PMID:19019919 NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587
JBrowse link
positive regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hip1 huntingtin interacting protein 1 involved_in ISO (PMID:14732715) ParkinsonsUK-UCL PMID:14732715 NCBI chrNW_004955456:14,389,282...14,529,317
Ensembl chrNW_004955456:14,392,921...14,529,213
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO (PMID:14732715) ParkinsonsUK-UCL PMID:14732715 NCBI chrNW_004955482:5,885,807...5,896,386
Ensembl chrNW_004955482:5,884,839...5,896,389
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23651497) MGI PMID:23651497 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695
JBrowse link
regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lox lysyl oxidase acts_upstream_of_or_within ISO (PMID:21665949) MGI PMID:21665949 NCBI chrNW_004955521:178,290...193,926
Ensembl chrNW_004955521:185,792...193,926
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12559
    cellular process 11998
      signal transduction 4038
        cell surface receptor signaling pathway 2194
          enzyme-linked receptor protein signaling pathway 859
            cell surface receptor protein tyrosine kinase signaling pathway 545
              platelet-derived growth factor receptor signaling pathway 65
                platelet-derived growth factor receptor-beta signaling pathway 14
                  VEGF-activated platelet-derived growth factor receptor-beta signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-beta signaling pathway 4
                  positive regulation of platelet-derived growth factor receptor-beta signaling pathway 3
                  regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway + 3
                  regulation of platelet-derived growth factor receptor-beta signaling pathway + 8
Path 2
Term Annotations click to browse term
  biological_process 12559
    biological regulation 9079
      regulation of biological process 8773
        signaling 4528
          signal transduction 4038
            cell surface receptor signaling pathway 2194
              enzyme-linked receptor protein signaling pathway 859
                cell surface receptor protein tyrosine kinase signaling pathway 545
                  platelet-derived growth factor receptor signaling pathway 65
                    platelet-derived growth factor receptor-beta signaling pathway 14
                      VEGF-activated platelet-derived growth factor receptor-beta signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-beta signaling pathway 4
                      positive regulation of platelet-derived growth factor receptor-beta signaling pathway 3
                      regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway + 3
                      regulation of platelet-derived growth factor receptor-beta signaling pathway + 8
paths to the root