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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet-derived growth factor receptor-beta signaling pathway
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Accession:GO:0035791 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-beta signaling pathway;   PDGFR-beta signaling pathway;   betaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-beta signalling pathway



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platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:24520051) RGD PMID:24520051 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24520051) RGD PMID:24520051 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731
JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within ISO
IMP
MGI:3610732 (MGI:3813418|PMID:18586678) RGD PMID:18586678 PMID:18586678 MGI:3813418, RGD:14390060 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO (PMID:2554309), (PMID:26599395) RGD PMID:2554309 PMID:26599395 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:14966296)
(MGI:3029644|PMID:14966296)
RGD PMID:14966296 MGI:3029644 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
negative regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glrx glutaredoxin IMP RGD PMID:16893901 RGD:9686048 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:4365879|PMID:19742316) RGD PMID:19742316 MGI:4365879 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Myocd myocardin involved_in IEA
ISO
GO_REF:0000107
(MGI:5644147|PMID:23825366)
Ensembl
RGD
PMID:23825366 GO_REF:0000107 MGI:5644147 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3029644|PMID:14966296)
UniProt
RGD
PMID:14966296 GO_REF:0000024 MGI:3029644 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19019919)
UniProt
Ensembl
RGD
PMID:19019919 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19019919)
UniProt
Ensembl
RGD
PMID:19019919 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO
GO_REF:0000024
(MGI:5284758|PMID:19019919)
UniProt
RGD
PMID:19019919 GO_REF:0000024 MGI:5284758 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
positive regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hip1 huntingtin interacting protein 1 involved_in ISO (PMID:14732715) RGD PMID:14732715 NCBI chr12:21,133,319...21,267,796
Ensembl chr12:21,133,406...21,267,725
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO (PMID:14732715) RGD PMID:14732715 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:5518963|PMID:23651497) RGD PMID:23651497 MGI:5518963 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lox lysyl oxidase acts_upstream_of_or_within ISO MGI:2657016 (MGI:5293278|PMID:21665949) RGD PMID:21665949 MGI:5293278 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    signaling 7439
      signal transduction 6860
        cell surface receptor signaling pathway 2773
          enzyme linked receptor protein signaling pathway 978
            transmembrane receptor protein tyrosine kinase signaling pathway 613
              platelet-derived growth factor receptor signaling pathway 63
                platelet-derived growth factor receptor-beta signaling pathway 14
                  VEGF-activated platelet-derived growth factor receptor-beta signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-beta signaling pathway 4
                  positive regulation of platelet-derived growth factor receptor-beta signaling pathway 3
                  regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway + 3
                  regulation of platelet-derived growth factor receptor-beta signaling pathway + 8
Path 2
Term Annotations click to browse term
  biological_process 19391
    biological regulation 13476
      regulation of biological process 12736
        regulation of cellular process 12198
          signal transduction 6860
            cell surface receptor signaling pathway 2773
              enzyme linked receptor protein signaling pathway 978
                transmembrane receptor protein tyrosine kinase signaling pathway 613
                  platelet-derived growth factor receptor signaling pathway 63
                    platelet-derived growth factor receptor-beta signaling pathway 14
                      VEGF-activated platelet-derived growth factor receptor-beta signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-beta signaling pathway 4
                      positive regulation of platelet-derived growth factor receptor-beta signaling pathway 3
                      regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway + 3
                      regulation of platelet-derived growth factor receptor-beta signaling pathway + 8
paths to the root