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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:platelet-derived growth factor receptor-alpha signaling pathway
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Accession:GO:0035790 term browser browse the term
Definition:The series of molecular signals initiated a ligand binding to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-alpha signaling pathway;   alphaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-alpha signalling pathway
 related_synonym: PDGFR-alpha signaling pathway

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platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:16,804,129...16,853,539
Ensembl chrNW_004936482:16,807,569...16,853,587 		JBrowse link
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:3,168,599...3,179,369
Ensembl chrNW_004936578:3,168,331...3,171,928 		JBrowse link
G Phf14 PHD finger protein 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22730381) Ensembl
MGI		 PMID:22730381 GO_REF:0000107 NCBI chrNW_004936761:585,261...768,794
Ensembl chrNW_004936761:561,443...768,792 		JBrowse link
regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:4,136,389...4,235,746
Ensembl chrNW_004936542:4,136,511...4,228,288 		JBrowse link
G Cblb Cbl proto-oncogene B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936701:1,157,790...1,353,375
Ensembl chrNW_004936701:1,157,797...1,353,388 		JBrowse link
G Ift20 intraflagellar transport 20 involved_in ISO (MGI:6108066|PMID:29237719) UniProt PMID:29237719 MGI:6108066 NCBI chrNW_004936538:4,484,484...4,491,688 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    cellular process 15075
      signal transduction 5702
        cell surface receptor signaling pathway 2527
          enzyme-linked receptor protein signaling pathway 938
            cell surface receptor protein tyrosine kinase signaling pathway 616
              platelet-derived growth factor receptor signaling pathway 63
                platelet-derived growth factor receptor-alpha signaling pathway 6
                  VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                  positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                  regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 15969
    biological regulation 11154
      regulation of biological process 10818
        signaling 6188
          signal transduction 5702
            cell surface receptor signaling pathway 2527
              enzyme-linked receptor protein signaling pathway 938
                cell surface receptor protein tyrosine kinase signaling pathway 616
                  platelet-derived growth factor receptor signaling pathway 63
                    platelet-derived growth factor receptor-alpha signaling pathway 6
                      VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                      positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                      regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
paths to the root