Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:platelet-derived growth factor receptor-alpha signaling pathway
go back to main search page
Accession:GO:0035790 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-alpha signaling pathway;   alphaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-alpha signalling pathway
 related_synonym: PDGFR-alpha signaling pathway


GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
 
platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:16,804,129...16,853,539 JBrowse link
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Phf14 PHD finger protein 14 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5426441|PMID:22730381) MGI
Ensembl
PMID:22730381 GO_REF:0000107 MGI:5426441 NCBI chrNW_004936761:585,261...768,794 JBrowse link
regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:4,136,389...4,235,746 JBrowse link
G Cblb Cbl proto-oncogene B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936701:1,157,790...1,353,375 JBrowse link
G Ift20 intraflagellar transport 20 involved_in ISO (MGI:6108066|PMID:29237719) UniProt PMID:29237719 MGI:6108066 NCBI chrNW_004936538:4,484,484...4,491,688 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14953
    signaling 5673
      signal transduction 5224
        cell surface receptor signaling pathway 2298
          enzyme linked receptor protein signaling pathway 865
            transmembrane receptor protein tyrosine kinase signaling pathway 544
              platelet-derived growth factor receptor signaling pathway 61
                platelet-derived growth factor receptor-alpha signaling pathway 6
                  VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                  positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                  regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 14953
    biological regulation 10655
      regulation of biological process 10116
        regulation of cellular process 9688
          signal transduction 5224
            cell surface receptor signaling pathway 2298
              enzyme linked receptor protein signaling pathway 865
                transmembrane receptor protein tyrosine kinase signaling pathway 544
                  platelet-derived growth factor receptor signaling pathway 61
                    platelet-derived growth factor receptor-alpha signaling pathway 6
                      VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                      positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                      regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
paths to the root