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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet-derived growth factor receptor-alpha signaling pathway
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Accession:GO:0035790 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-alpha signaling pathway;   alphaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-alpha signalling pathway
 related_synonym: PDGFR-alpha signaling pathway



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platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA Ensembl
Ensembl
GOC
GOC
GO_REF:0000107 GO_REF:0000108 NCBI chr 8:40,966,568...41,021,440
Ensembl chr 8:40,967,493...41,021,442
JBrowse link
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in IEA
ISS
Ensembl
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G PHF14 PHD finger protein 14 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5426441|PMID:22730381) Ensembl
Ensembl
MGI
PMID:22730381 GO_REF:0000107 MGI:5426441 NCBI chr 9:80,677,185...80,866,160
Ensembl chr 9:80,677,967...80,866,146
JBrowse link
regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:46,416,937...46,512,855
Ensembl chr 9:46,404,999...46,512,834
JBrowse link
G CBLB Cbl proto-oncogene B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:153,480,525...153,700,115
Ensembl chr13:153,395,978...153,700,064
JBrowse link
G IFT20 intraflagellar transport 20 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:44,609,586...44,616,685
Ensembl chr12:44,609,586...44,616,669
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16975
    signaling 6847
      signal transduction 6297
        cell surface receptor signaling pathway 2582
          enzyme linked receptor protein signaling pathway 960
            transmembrane receptor protein tyrosine kinase signaling pathway 602
              platelet-derived growth factor receptor signaling pathway 60
                platelet-derived growth factor receptor-alpha signaling pathway 6
                  VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                  positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                  regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 16975
    biological regulation 12436
      regulation of biological process 11807
        regulation of cellular process 11348
          signal transduction 6297
            cell surface receptor signaling pathway 2582
              enzyme linked receptor protein signaling pathway 960
                transmembrane receptor protein tyrosine kinase signaling pathway 602
                  platelet-derived growth factor receptor signaling pathway 60
                    platelet-derived growth factor receptor-alpha signaling pathway 6
                      VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                      positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                      regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
paths to the root