Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:platelet-derived growth factor receptor-alpha signaling pathway
go back to main search page
Accession:GO:0035790 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-alpha signaling pathway;   alphaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-alpha signalling pathway
 related_synonym: PDGFR-alpha signaling pathway



show annotations for term's descendants           Sort by:
 
platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor, alpha polypeptide involved_in ISO
IDA
(MGI:5294530|PMID:20110689) MGI
UniProt
PMID:20110689 GO_REF:0000096 MGI:4834177 MGI:5294530 NCBI chr 5:75,151,322...75,198,206
Ensembl chr 5:75,152,292...75,198,215
JBrowse link
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in IDA (MGI:4943654|PMID:19460854) UniProt PMID:19460854 MGI:4943654 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Phf14 PHD finger protein 14 acts_upstream_of_or_within IMP (MGI:5426441|PMID:22730381) MGI PMID:22730381 MGI:5426441 NCBI chr 6:11,907,725...12,100,156
Ensembl chr 6:11,907,809...12,081,205
JBrowse link
regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Casitas B-lineage lymphoma involved_in IMP (MGI:6108066|PMID:29237719) UniProt PMID:29237719 MGI:6108066 NCBI chr 9:44,142,976...44,234,259
Ensembl chr 9:44,142,976...44,234,049
JBrowse link
G Cblb Casitas B-lineage lymphoma b involved_in IMP (MGI:6108066|PMID:29237719) UniProt PMID:29237719 MGI:6108066 NCBI chr16:52,031,230...52,208,047
Ensembl chr16:52,031,225...52,208,048
JBrowse link
G Ift20 intraflagellar transport 20 involved_in IMP (MGI:6108066|PMID:29237719) UniProt PMID:29237719 MGI:6108066 NCBI chr11:78,536,361...78,541,732
Ensembl chr11:78,536,361...78,541,737
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28652
    signaling 7219
      signal transduction 6595
        cell surface receptor signaling pathway 2853
          enzyme linked receptor protein signaling pathway 989
            transmembrane receptor protein tyrosine kinase signaling pathway 616
              platelet-derived growth factor receptor signaling pathway 65
                platelet-derived growth factor receptor-alpha signaling pathway 6
                  VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                  positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                  regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 28652
    biological regulation 13396
      regulation of biological process 12739
        regulation of cellular process 12168
          signal transduction 6595
            cell surface receptor signaling pathway 2853
              enzyme linked receptor protein signaling pathway 989
                transmembrane receptor protein tyrosine kinase signaling pathway 616
                  platelet-derived growth factor receptor signaling pathway 65
                    platelet-derived growth factor receptor-alpha signaling pathway 6
                      VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                      positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                      regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
paths to the root