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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet-derived growth factor receptor-alpha signaling pathway
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Accession:GO:0035790 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-alpha signaling pathway;   alphaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-alpha signalling pathway
 related_synonym: PDGFR-alpha signaling pathway



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platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRA platelet derived growth factor receptor alpha involved_in IMP
IEA
(PMID:2554309) UniProt
Ensembl
UniProt
PMID:2554309 GO_REF:0000107 NCBI chr 4:54,229,127...54,298,245
Ensembl chr 4:54,229,280...54,298,245
JBrowse link
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G PHF14 PHD finger protein 14 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5426441|PMID:22730381) Ensembl
Ensembl
MGI
PMID:22730381 GO_REF:0000107 MGI:5426441 NCBI chr 7:10,973,872...11,169,618
Ensembl chr 7:10,973,336...11,169,623
JBrowse link
regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
JBrowse link
G CBLB Cbl proto-oncogene B involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:105,655,461...105,869,552
Ensembl chr 3:105,655,461...105,869,552
JBrowse link
G IFT20 intraflagellar transport 20 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr17:28,328,326...28,335,472
Ensembl chr17:28,328,325...28,335,489
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18659
    signaling 6985
      signal transduction 6362
        cell surface receptor signaling pathway 3073
          enzyme linked receptor protein signaling pathway 1059
            transmembrane receptor protein tyrosine kinase signaling pathway 671
              platelet-derived growth factor receptor signaling pathway 66
                platelet-derived growth factor receptor-alpha signaling pathway 6
                  VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                  positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                  regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 18659
    biological regulation 13218
      regulation of biological process 12506
        regulation of cellular process 11965
          signal transduction 6362
            cell surface receptor signaling pathway 3073
              enzyme linked receptor protein signaling pathway 1059
                transmembrane receptor protein tyrosine kinase signaling pathway 671
                  platelet-derived growth factor receptor signaling pathway 66
                    platelet-derived growth factor receptor-alpha signaling pathway 6
                      VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                      positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                      regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
paths to the root