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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet-derived growth factor receptor-alpha signaling pathway
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Accession:GO:0035790 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-alpha signaling pathway;   alphaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-alpha signalling pathway
 related_synonym: PDGFR-alpha signaling pathway



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platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA Ensembl
Ensembl
GOC
GOC
GO_REF:0000107 GO_REF:0000108 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278
JBrowse link
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in IEA
ISS
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844
JBrowse link
G PHF14 PHD finger protein 14 acts_upstream_of_or_within ISO (MGI:5426441|PMID:22730381) MGI PMID:22730381 MGI:5426441 NCBI chr14:25,907,955...26,089,666
Ensembl chr14:25,914,188...26,125,766
JBrowse link
regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene involved_in ISO (MGI:6108066|PMID:29237719) UniProt PMID:29237719 MGI:6108066 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G CBLB Cbl proto-oncogene B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810
JBrowse link
G IFT20 intraflagellar transport 20 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:42,581,117...42,587,830
Ensembl chr 9:42,581,433...42,587,804
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16237
    signaling 6214
      signal transduction 5651
        cell surface receptor signaling pathway 2545
          enzyme linked receptor protein signaling pathway 958
            transmembrane receptor protein tyrosine kinase signaling pathway 604
              platelet-derived growth factor receptor signaling pathway 61
                platelet-derived growth factor receptor-alpha signaling pathway 6
                  VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                  positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                  regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 16237
    biological regulation 11773
      regulation of biological process 11134
        regulation of cellular process 10657
          signal transduction 5651
            cell surface receptor signaling pathway 2545
              enzyme linked receptor protein signaling pathway 958
                transmembrane receptor protein tyrosine kinase signaling pathway 604
                  platelet-derived growth factor receptor signaling pathway 61
                    platelet-derived growth factor receptor-alpha signaling pathway 6
                      VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                      positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                      regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
paths to the root