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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet-derived growth factor receptor-alpha signaling pathway
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Accession:GO:0035790 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor-alpha signaling pathway;   alphaPDGF receptor signaling pathway;   platelet-derived growth factor receptor-alpha signalling pathway
 related_synonym: PDGFR-alpha signaling pathway



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platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097
JBrowse link
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in ISO (MGI:4943654|PMID:19460854) UniProt PMID:19460854 MGI:4943654 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G PHF14 PHD finger protein 14 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5426441|PMID:22730381) MGI
Ensembl
PMID:22730381 GO_REF:0000107 MGI:5426441 NCBI chr 7:11,608,934...11,822,039
Ensembl chr 7:10,972,503...11,169,377
JBrowse link
regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:114,044,996...114,149,204
Ensembl chr11:117,973,187...118,074,671
JBrowse link
G CBLB Cbl proto-oncogene B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:102,752,406...102,966,414
Ensembl chr 3:109,690,120...109,905,191
JBrowse link
G IFT20 intraflagellar transport 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,438,960...28,446,113
Ensembl chr17:28,941,303...28,948,129
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15229
    signaling 5442
      signal transduction 4990
        cell surface receptor signaling pathway 2369
          enzyme linked receptor protein signaling pathway 866
            transmembrane receptor protein tyrosine kinase signaling pathway 543
              platelet-derived growth factor receptor signaling pathway 61
                platelet-derived growth factor receptor-alpha signaling pathway 6
                  VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                  negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                  positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                  regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 15229
    biological regulation 10799
      regulation of biological process 10214
        regulation of cellular process 9752
          signal transduction 4990
            cell surface receptor signaling pathway 2369
              enzyme linked receptor protein signaling pathway 866
                transmembrane receptor protein tyrosine kinase signaling pathway 543
                  platelet-derived growth factor receptor signaling pathway 61
                    platelet-derived growth factor receptor-alpha signaling pathway 6
                      VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway 0
                      negative regulation of platelet-derived growth factor receptor-alpha signaling pathway 2
                      positive regulation of platelet-derived growth factor receptor-alpha signaling pathway 0
                      regulation of platelet-derived growth factor receptor-alpha signaling pathway + 5
paths to the root